Nickel(II) chloride hexahydrate Property

Melting point:

140℃ -H{2}O

Density 

1,92 g/cm³

storage temp. 

Store below +30°C.

solubility 

2540g/l

form 

Solution

color 

Green

PH

4.9 (100g/l, H2O, 20℃)

Water Solubility 

2540 G/L (20 ºC)

Sensitive 

Hygroscopic

Merck 

14,6505

Exposure limits

ACGIH: TWA 0.1 mg/m3
NIOSH: IDLH 10 mg/m3; TWA 0.015 mg/m3

Stability:

Stable. Hygroscopic. Incompatible with peroxides.

InChIKey

LAIZPRYFQUWUBN-UHFFFAOYSA-L

CAS DataBase Reference

7791-20-0(CAS DataBase Reference)

EPA Substance Registry System

Nickel chloride (NiCl2), hexahydrate (7791-20-0)

Safety

Hazard Codes 

T,N,Xi

Risk Statements 

45-25-36/38-43-50/53-68-48/23-42/43-38-23/25-61-49

Safety Statements 

53-36/37-45-60-61-37-29-24

RIDADR 

UN 3288 6.1/PG 3

WGK Germany 

3

RTECS 

QR6480000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

28273500

Toxicity

LD50 orally in Rabbit: 186 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H341Suspected of causing genetic defects

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

Nickel(II) chloride hexahydrate Chemical Properties,Usage,Production

Chemical Properties

Green solid

Uses

Nickel(II) chloride hexahydrate has been used:

• in the preparation of nickel platting solution for galvanostatically coating nickel inside the reduced carbon layer during the synthesis of multiwall carbon nanotube micromotors
• in screening of metals for inflammatory effect on vascular endothelial cells
• as an additive in artificial cerebrospinal fluid (ACSF) to analyse excitatory post synaptic currents (EPSPs) in the hippocampus slices

Uses

Nickel(II) chloride hexahydrate may be employed as a catalyst in the high yield synthesis of tetra-substituted pyrrole derivatives. It may be used for the conversion of tetrahydropyranyl (THP) and tert-butyldimethylsilyl (TBS) ethers to the corresponding hydroxyl compounds.

Uses

Anhydr salt as absorbent for NH3 in gas masks. Hexahydrate for nickel electroplating; manufacture of nickel catalysts.

Definition

ChEBI: A hydrate of nickel chloride containing nickel (in the +2 oxidation state), chloride and water moeities in the ratio 1:2:6.

General Description

Nickel(II) chloride hexahydrate is a nickel salt that can be used as a catalyst. It is cost effective and can be used in a variety of industrial processes. It can also be used in cross-coupling reactions.

Hazard

Confirmed carcinogen.

Biochem/physiol Actions

Nickel (Ni) is an essential trace element that plays an important role in the structure and function of DNA, RNA and protein. It has toxic effects on renal, pulmonary and cardiovascular system at higher concentrations. Nickel is implicated in carcinogenesis. Ni2+ ions is a clastogenic agent. Nickel ions (Ni2+) is a non-specific voltage-gated calcium channel blocker.

Safety Profile

Confirmed human carcinogen. Poison by intraperitoneal and intravenous routes. Experimental reproductive effects. Mutation data reported. Violent reaction with potassium. When heated to decomposition it emits very toxic fumes of Cl-. See also NICKEL COMPOUNDS and CHLORIDES.

Purification Methods

It crystallises from dilute HCl to form the green hexahydrate. At 70o this dehydrates to the tetrahydrate, and at higher temperatures it forms the anhydrous salt. It sublimes in yellow hexagonal scales in a stream of HCl. Store it in a desiccator as it is deliquescent. [Hart & Partington J Chem Soc 104 1943.]