Raptinal
- Product Name
- Raptinal
- CAS No.
- 1176-09-6
- Chemical Name
- Raptinal
- Synonyms
- Raptinal;Raptinal, 10 mM in DMSO;[9,9'-Bi-9H-fluorene]-9,9'-dicarboxaldehyde;9H,9'H-[9,9'-Bifluorene]-9,9'-dicarbaldehyde
- CBNumber
- CB03969481
- Molecular Formula
- C28H18O2
- Formula Weight
- 386.44
- MOL File
- 1176-09-6.mol
Raptinal Property
- Melting point:
- 219 °C
- Boiling point:
- 531.3±50.0 °C(Predicted)
- Density
- 1.378±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 33.33 mg/mL (86.25 mM; Need ultrasonic)
- form
- powder to crystal
- color
- White to Almost white
Safety
- HS Code
- 2912.29.6090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R0199
- Product name
- Raptinal
- Purity
- >96.0%(HPLC)
- Packaging
- 25mg
- Price
- $197
- Updated
- 2024/03/01
- Product number
- R0199
- Product name
- Raptinal
- Purity
- >96.0%(HPLC)
- Packaging
- 100mg
- Price
- $575
- Updated
- 2024/03/01
- Product number
- 42193
- Product name
- Raptinal,≥96%(HPLC)
- Purity
- ≥96%(HPLC)
- Packaging
- 100MG
- Price
- $602.2
- Updated
- 2021/12/16
- Product number
- 1136CC
- Product name
- 9-(9-Formylfluoren-9-yl)fluorene-9-carbaldehyde
- Packaging
- 100mg
- Price
- $818
- Updated
- 2021/12/16
- Product number
- 1136CC
- Product name
- 9-(9-Formylfluoren-9-yl)fluorene-9-carbaldehyde
- Packaging
- 25mg
- Price
- $313
- Updated
- 2021/12/16
Raptinal Chemical Properties,Usage,Production
Uses
Raptinal showed complete cytochrome c release within 30 minutes and caspase-3 activation within one hour of exposure (10 μM). Despite its general cytotoxicity in both cancer and non-cancer cell cultures (Cell death induction EC50 = 0.6-3.4 μM in 24 hr), no hematologic toxicity was observed 7 days following single 60 mg/kg i.v. dosing in mice. Studies show th at daily i.p. injection (20 mg/kg) is efficacious in suppressing murine B16-F10 melanoma and 4T1 breast cancer expansion in vivo (by ~60% and 50% in 6 days, respectively).
Biological Activity
Raptinal is a cell-permeable bifluorene-dicarbaldehyde compound th at acts as a rapid activator of mitochondrial pathway-mediated intrinsic apoptosis.
Raptinal Preparation Products And Raw materials
Raw materials
Preparation Products
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