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GIGAVLKVLTTGLPALISWIKRKRQ-OH

Product Name
GIGAVLKVLTTGLPALISWIKRKRQ-OH
CAS No.
123168-46-7
Chemical Name
GIGAVLKVLTTGLPALISWIKRKRQ-OH
Synonyms
MELITTIN;MELITTIN (FREE ACID);Melittin trifluoroacetate;GIGAVLKVLTTGLPALISWIKRKRQ-OH;GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN: GIGAVLKVLTTGLPALISWIKRKRQQ
CBNumber
CB0401937
Molecular Formula
C131H228N38O32
Formula Weight
2847.45
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PRK0000269
Product name
MELITTIN FREE ACID
Purity
95.00%
Packaging
0.5MG
Price
$654.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PRK0000269
Product name
MELITTIN FREE ACID
Purity
95.00%
Packaging
1MG
Price
$796
Updated
2021/12/16
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GIGAVLKVLTTGLPALISWIKRKRQ-OH Chemical Properties,Usage,Production

Uses

Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways[1][2].

in vivo

Melittin (intraperitoneal inoculation) increases 13,14-dihydro-15-keto-PGE2 levels in peripheral blood of mice[1].

References

[1] Hassid A, Levine L. Stimulation of phospholipase activity and prostaglandin biosynthesis by melittin in cell culture and in vivo. Res Commun Chem Pathol Pharmacol. 1977. PMID:928951
[2] Memariani H, Memariani M. Anti-fungal properties and mechanisms of melittin. Appl Microbiol Biotechnol. 2020 Aug;104(15):6513-6526. DOI:10.1007/s00253-020-10701-0

GIGAVLKVLTTGLPALISWIKRKRQ-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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GIGAVLKVLTTGLPALISWIKRKRQ-OH Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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GL Biochem (Shanghai) Ltd
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21-61263452 13641803416
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86-21-61263399
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ymbetter@glbiochem.com
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BOC Sciences
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1-631-485-4226; 16314854226
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info@bocsci.com
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United States
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Nanjing Peptide Biotech Ltd.
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028-62328193
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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Nanchang Tianzhen Biotechnology Co., Ltd
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Nanjing TGpeptide Biotechnology Co.,Ltd.
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TCI (Shanghai) Chemical Trading Co., Ltd.
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123168-46-7, GIGAVLKVLTTGLPALISWIKRKRQ-OHRelated Search:


  • MELITTIN
  • MELITTIN (FREE ACID)
  • GIGAVLKVLTTGLPALISWIKRKRQ-OH
  • GLY-ILE-GLY-ALA-VAL-LEU-LYS-VAL-LEU-THR-THR-GLY-LEU-PRO-ALA-LEU-ILE-SER-TRP-ILE-LYS-ARG-LYS-ARG-GLN-GLN: GIGAVLKVLTTGLPALISWIKRKRQQ
  • Melittin trifluoroacetate
  • 123168-46-7
  • 23168-46-7