4-Pyridyl acetone

Description Preparation

Product Name: 4-Pyridyl acetone
CAS No.: 6304-16-1
Chemical Name: 4-Pyridyl acetone
Synonyms: 1-(PYRIDIN-4-YL)PROPAN-2-ONE;1-(4-Pyridyl)acetone;1-(4-Pyridyl)-2-acetone;1-(4-PYRIDINYL)-2-PROPANONE;Einecs 228-605-7;-Pyridyl acetone;4-Pyridinolacetone;4-ACETONYLPYRIDINE;(4-PYRIDYL)ACETONE;4-pyridinyl acetone
CBNumber: CB0402505
Molecular Formula: C8H9NO
Formula Weight: 135.16
MOL File: 6304-16-1.mol

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4-Pyridyl acetone Property

Melting point:: 13°C
Boiling point:: 143°C 20mm
Density: 1.046±0.06 g/cm3(Predicted)
refractive index: 1.5225
Flash point:: 143°C/20mm
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Oil
pka: 4.90±0.10(Predicted)
color: Light Brown to Brown
Water Solubility: Slightly soluble in water.
BRN: 110960
InChI: InChI=1S/C8H9NO/c1-7(10)6-8-2-4-9-5-3-8/h2-5H,6H2,1H3
InChIKey: ILRVKOYYFFNXDB-UHFFFAOYSA-N
SMILES: C(C1C=CN=CC=1)C(=O)C
CAS DataBase Reference: 6304-16-1(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39-37
HS Code: 29337900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P2039
Product name: (4-Pyridyl)acetone
Purity: >98.0%(GC)
Packaging: 1g
Price: $35
Updated: 2021/12/16

TCI Chemical

Product number: P2039
Product name: (4-Pyridyl)acetone
Purity: >98.0%(GC)
Packaging: 5g
Price: $136
Updated: 2021/12/16

TRC

Product number: P991845
Product name: (4-Pyridyl)acetone
Packaging: 5g
Price: $85
Updated: 2021/12/16

TRC

Product number: P991845
Product name: (4-Pyridyl)acetone
Packaging: 25g
Price: $255
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 66864
Product name: (4-Pyridyl)acetone
Packaging: 25g
Price: $290
Updated: 2021/12/16

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4-Pyridyl acetone Chemical Properties,Usage,Production

Description

1-(4-pyridyl)acetone is a yellow liquid, which is a key intermediate for synthesizing cardiac drug Milrinone.

Preparation

4-Pyridyl acetone can be prepared by reacting with 4-picoline and phenyllithium and ethyl acetate.

Physical properties

4-pyridyl acetone is a Light yellow to yellow liquid.

Chemical Properties

Liquid. Boiling point 130-132℃/1.5kPa.

Uses

(4-Pyridyl)acetone is a reactant in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 3297, 1984 DOI: 10.1016/S0040-4039(01)81368-X

4-Pyridyl acetone Preparation Products And Raw materials

Raw materials

Hexamethylphosphoramide Ethanol 4-Methylpyridine Phenyllithium Chloroform Diisopropylamine Tetrahydrofuran Ethyl acetate Acetic acid PETROLEUM ETHER n-Butyllithium

Preparation Products

Milrinone

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View Lastest Price from 4-Pyridyl acetone manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Pyridyl acetone 6304-16-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-13

Nanjing Kaitian Chemical Co., LTD

Product: 1-(4-Pyridyl)acetone 6304-16-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2tons
Release date: 2022-12-06

Dideu Industries Group Limited

Product: 4-Pyridyl acetone 6304-16-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-25

6304-16-1, 4-Pyridyl acetoneRelated Search:

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1-(4-Pyridyl)-2-propanone

4-Pyridinolacetone

(4-Pyridyl)acetone,98%

1-(4-Pyridinyl)-2-propanone CAS:

(4-PYRIDINEYL)-ACETONE

1-(4-Pyridyl)-2-acetone

Einecs 228-605-7

1-pyridin-4-ylacetone

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4-ACETONYLPYRIDINE

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(PYRIDIN-4-YL)ACETONE

(4-PYRIDYL)ACETONE

1-(PYRIDIN-4-YL)PROPAN-2-ONE

Milrinone Impurity K

pyridin-4-yl-propan-2-one

1-pyridin-4-yl-2-propanone

1-(4-Pyridyl)acetone

1-(4-PYRIDINYL)-2-PROPANONE

(4-Pyridyl)acetone&gt

2-Propanone, 1-(4-pyridinyl)-

4-Pyridyl acetone ISO 9001：2015 REACH

4-pyridinyl acetone

CAS 6304-16-1 4-Pyridyl acetone

(4-Pyridyl)acetone OR [1-(4-pyridyl)-2-propanone

6304-16-1

Pyridines