3-ACETYLDEOXYNIVALENOL Property

Melting point:

185.75°C

Boiling point:

394.5°C (rough estimate)

Density 

1.2179 (rough estimate)

refractive index 

1.4790 (estimate)

Flash point:

2 °C

storage temp. 

-20°C

solubility 

DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml

pka

11.84±0.70(Predicted)

LogP

-0.448 (est)

Safety

Hazard Codes 

T,Xn,F

Risk Statements 

23/24/25-36-20/21/22-11

Safety Statements 

36/37-45-26-16

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

RTECS 

YD0150000

HazardClass 

6.1(a)

PackingGroup 

I

HS Code 

29329990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

3-ACETYLDEOXYNIVALENOL Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

3-Acetyldeoxynivalenol solution may be used as an analytical reference standard for the quantification of the analyte in bovine milk using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).

Uses

3-Acetyldeoxynivalenol is a trichothecene mycotoxin that is produced in a plant-pathogenic fungus, Fusarium graminearum Schwabe.

Definition

ChEBI: 3-acetyldeoxynivalenol is a trichothecene mycotoxin that is deoxynivalenol acetylated on the oxygen at C-3. A skin and eye irritant, along with its 15-acetyl regioisomer and its parent deoxynivalenol it is considered among the most commonly and widely distributed cereal contaminants. It has a role as an epitope and a mycotoxin. It is functionally related to a deoxynivalenol.

General Description

3-Acetyldeoxynivalenol is a trichothecene mycotoxin, secreted by Fusarium species. It stimulates the activation of c-Jun N-terminal kinase (JNK)/ p38 mitogen-activated protein kinases and prevents protein synthesis. 3-Acetyldeoxynivalenol is a weak inducer of apoptosis.