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N,N'-DINITROSOPIPERAZINE

Product Name
N,N'-DINITROSOPIPERAZINE
CAS No.
140-79-4
Chemical Name
N,N'-DINITROSOPIPERAZINE
Synonyms
1,4-DINITROSOPIPERAZINE;Dinitrosopiperazine;Dnpz;nsc339;NSC 339;usafdo-36;USAF do-36;Dinitrosopiperazin;TIMTEC-BB SBB008187;Piperazine Impurity 4
CBNumber
CB0420996
Molecular Formula
C4H8N4O2
Formula Weight
144.13
MOL File
140-79-4.mol
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N,N'-DINITROSOPIPERAZINE Property

Melting point:
208-210°C
Boiling point:
262.72°C (rough estimate)
Density 
1.4165 (rough estimate)
refractive index 
1.8500 (estimate)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
-4.82±0.70(Predicted)
color 
White to Pale Yellow
Water Solubility 
5.765g/L(24 ºC)
Stability:
Hygroscopic
InChI
InChI=1S/C4H8N4O2/c9-5-7-1-2-8(6-10)4-3-7/h1-4H2
InChIKey
WNSYEWGYAFFSSQ-UHFFFAOYSA-N
SMILES
N1(N=O)CCN(N=O)CC1
CAS DataBase Reference
140-79-4
EPA Substance Registry System
Piperazine, 1,4-dinitroso- (140-79-4)
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Safety

Hazardous Substances Data
140-79-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H350May cause cancer

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D480420
Product name
1,4-Dinitrosopiperazine
Packaging
500mg
Price
$105
Updated
2021/12/16
TRC
Product number
D480420
Product name
1,4-Dinitrosopiperazine
Packaging
2g
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22439
Product name
1,4-Dinitrosopiperazine
Packaging
500mg
Price
$115
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22439
Product name
1,4-Dinitrosopiperazine
Packaging
1g
Price
$199.9
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22439
Product name
1,4-Dinitrosopiperazine
Packaging
2g
Price
$363.4
Updated
2021/12/16
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N,N'-DINITROSOPIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, subcutaneous, and intraperitoned routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NNITROSO COMPOUNDS.

in vivo

N,N'-Dinitrosopiperazine (injected into the tail veins; 40 mg/kg; 30 days) inhibits cell motility and invasion, and facilitates NPC metastasis in vivo. From a IHC result, Phospho-LYRIC expression is higher in the metastatic tumors of DNP-treated mice than in those of the untreated control mice[1].

Animal Model:BABL/c nude mice injected with labeled 6-10B cell suspensions (1?×?104?cells) with or without DNP(40 mg/kg)[1]
Dosage:40 mg/kg
Administration:Injected into the tail veins; 30 days
Result:Induced LYRIC phosphorylation at serine 568 associated with NPC metastasis in vivo.

N,N'-DINITROSOPIPERAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-DINITROSOPIPERAZINE Suppliers

Canada 1 China 61 Europe 1 France 1 Germany 1 India 4 South Korea 1 Sweden 1 Ukraine 1 United Kingdom 2 United States 6 Global 80
Shenzhen Excellent Biomedical Technology Co., Ltd.
Tel
0755-26050679 18318671572
Email
2850803126@qq.com
Country
China
ProdList
10001
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5158
Advantage
50
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8593
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Beijing Ditai Pharmaceutical Technology Co., Ltd.
Tel
010-13810111756 13810111756
Fax
13810111756
Email
1601345388@qq.com
Country
China
ProdList
302
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
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View Lastest Price from N,N'-DINITROSOPIPERAZINE manufacturers

Moxin Chemicals
Product
1,4-Dinitrosopiperazine 140-79-4
Price
US $0.00-0.00/mg
Min. Order
1mg
Purity
>95% HPLC
Supply Ability
10000
Release date
2025-04-21
Henan Fengda Chemical Co., Ltd
Product
N,N'-DINITROSOPIPERAZINE 140-79-4
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28

140-79-4, N,N'-DINITROSOPIPERAZINERelated Search:

N-NITROSO-METHYL-ETHYLAMINE N-NITROSODIETHYLAMINE N,N'-DINITROSOPIPERAZINE N-NITROSODIMETHYLAMINE N,N-DINITROPIPERAZINE 1,4-diaminopiperazine hydrate 1-AMINO PIPERAZINE 1-nitrosopiperazine N,N-DIETHYLHYDRAZINE 2-METHYL-1,4-DINITROSOPIPERAZINE 2,3,5,6-Tetramethyl-1,4-dinitrosopiperazine (2R,6R)-2,6-DIMETHYL-1,4-DINITROSOPIPERAZINE 2-NITRO-1,4-DINITROSOPIPERAZINE (2R,5S)-2,5-DIMETHYL-1,4-DINITROSOPIPERAZINE 2,3-DIMETHYL-1,4-DINITROSOPIPERAZINE 1,4-DINITROSOPIPERAZINE-2-CARBOXYLIC ACID (2R,6S)-2,6-DIMETHYL-1,4-DINITROSOPIPERAZINE 2,6-DIMETHYL-1,4-DINITROSOPIPERAZINE

  • N,N'-DINITROSOPIPERAZINE
  • TIMTEC-BB SBB008187
  • 1,4-dinitroso-piperazin
  • Dinitrosopiperazin
  • Dinitrosopiperazine
  • Dnpz
  • NSC 339
  • nsc339
  • USAF do-36
  • usafdo-36
  • 1,4-DINITROSOPIPERAZINE
  • Dinitrosopiperazine: (Piperazine, 1,4-dinitroso-)
  • 1,4-dinitrosopiperidine
  • Piperazine Impurity 4
  • Piperazine, 1,4-dinitroso-
  • N- Nitrosopiperazine DIMER
  • 140-79-4---N,N'-DINITROSOPIPERAZINE
  • N,N-Dinitroso-Piperazin
  • Piperazine Impurity 24
  • N,N'-Dinitrosopiperazine (DMP)
  • 1,4-Dinitrosopiperazine in acetonitrile
  • Rifapentine Impurity 7
  • N,N'-Dinitrosopiperazine (DMP)
  • N,N'-Dinitrosopiperazine Solution (1 mL (1 mg/mL)) in Methanol : 1,4-Dinitrosopiperazine
  • 140-79-4
  • C4H8N2NO2
  • Heterocycles
  • Mutagenesis Research Chemicals