ChemicalBook > CAS DataBase List > N,N'-DINITROSOPIPERAZINE

N,N'-DINITROSOPIPERAZINE

Product Name: N,N'-DINITROSOPIPERAZINE
CAS No.: 140-79-4
Chemical Name: N,N'-DINITROSOPIPERAZINE
Synonyms: 1,4-DINITROSOPIPERAZINE;Dinitrosopiperazine;Dnpz;nsc339;NSC 339;usafdo-36;USAF do-36;Dinitrosopiperazin;TIMTEC-BB SBB008187;Piperazine Impurity 4
CBNumber: CB0420996
Molecular Formula: C4H8N4O2
Formula Weight: 144.13
MOL File: 140-79-4.mol

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N,N'-DINITROSOPIPERAZINE Property

Melting point:: 208-210°C
Boiling point:: 262.72°C (rough estimate)
Density: 1.4165 (rough estimate)
refractive index: 1.8500 (estimate)
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: -4.82±0.70(Predicted)
color: White to Pale Yellow
Water Solubility: 5.765g/L(24 ºC)
Stability:: Hygroscopic
InChI: InChI=1S/C4H8N4O2/c9-5-7-1-2-8(6-10)4-3-7/h1-4H2
InChIKey: WNSYEWGYAFFSSQ-UHFFFAOYSA-N
SMILES: N1(N=O)CCN(N=O)CC1
CAS DataBase Reference: 140-79-4
EPA Substance Registry System: Piperazine, 1,4-dinitroso- (140-79-4)

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Safety

Hazardous Substances Data: 140-79-4(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H350May cause cancer

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D480420
Product name: 1,4-Dinitrosopiperazine
Packaging: 500mg
Price: $105
Updated: 2021/12/16

TRC

Product number: D480420
Product name: 1,4-Dinitrosopiperazine
Packaging: 2g
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22439
Product name: 1,4-Dinitrosopiperazine
Packaging: 500mg
Price: $115
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22439
Product name: 1,4-Dinitrosopiperazine
Packaging: 1g
Price: $199.9
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22439
Product name: 1,4-Dinitrosopiperazine
Packaging: 2g
Price: $363.4
Updated: 2021/12/16

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N,N'-DINITROSOPIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, subcutaneous, and intraperitoned routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NNITROSO COMPOUNDS.

in vivo

N,N'-Dinitrosopiperazine (injected into the tail veins; 40 mg/kg; 30 days) inhibits cell motility and invasion, and facilitates NPC metastasis in vivo. From a IHC result, Phospho-LYRIC expression is higher in the metastatic tumors of DNP-treated mice than in those of the untreated control mice^[1].

Animal Model:	BABL/c nude mice injected with labeled 6-10B cell suspensions (1?×?10⁴?cells) with or without DNP(40 mg/kg)^[1]
Dosage:	40 mg/kg
Administration:	Injected into the tail veins; 30 days
Result:	Induced LYRIC phosphorylation at serine 568 associated with NPC metastasis in vivo.

N,N'-DINITROSOPIPERAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-DINITROSOPIPERAZINE Suppliers

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View Lastest Price from N,N'-DINITROSOPIPERAZINE manufacturers

Moxin Chemicals

Product: 1,4-Dinitrosopiperazine 140-79-4
Price: US $0.00-0.00/mg
Min. Order: 1mg
Purity: >95% HPLC
Supply Ability: 10000
Release date: 2025-04-21

Henan Fengda Chemical Co., Ltd

Product: N,N'-DINITROSOPIPERAZINE 140-79-4
Price: US $6.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

140-79-4, N,N'-DINITROSOPIPERAZINERelated Search:

N,N'-DINITROSOPIPERAZINE

TIMTEC-BB SBB008187

1,4-dinitroso-piperazin

Dinitrosopiperazin

Dinitrosopiperazine

Dnpz

NSC 339

nsc339

USAF do-36

usafdo-36

1,4-DINITROSOPIPERAZINE

Dinitrosopiperazine: (Piperazine, 1,4-dinitroso-)

1,4-dinitrosopiperidine

Piperazine Impurity 4

Piperazine, 1,4-dinitroso-

N- Nitrosopiperazine DIMER

140-79-4---N,N'-DINITROSOPIPERAZINE

N,N-Dinitroso-Piperazin

Piperazine Impurity 24

N,N'-Dinitrosopiperazine (DMP)

1,4-Dinitrosopiperazine in acetonitrile

Rifapentine Impurity 7

N,N'-Dinitrosopiperazine (DMP)

N,N'-Dinitrosopiperazine Solution (1 mL (1 mg/mL)) in Methanol : 1,4-Dinitrosopiperazine

140-79-4

C4H8N2NO2

Heterocycles

Mutagenesis Research Chemicals