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N,N'-DINITROSOPIPERAZINE

Product Name
N,N'-DINITROSOPIPERAZINE
CAS No.
140-79-4
Chemical Name
N,N'-DINITROSOPIPERAZINE
Synonyms
1,4-DINITROSOPIPERAZINE;Dinitrosopiperazine;Dnpz;nsc339;NSC 339;usafdo-36;USAF do-36;Dinitrosopiperazin;TIMTEC-BB SBB008187;Piperazine Impurity 4
CBNumber
CB0420996
Molecular Formula
C4H8N4O2
Formula Weight
144.13
MOL File
140-79-4.mol
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N,N'-DINITROSOPIPERAZINE Property

Melting point:
208-210°C
Boiling point:
262.72°C (rough estimate)
Density 
1.4165 (rough estimate)
refractive index 
1.8500 (estimate)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
-4.82±0.70(Predicted)
color 
White to Pale Yellow
Water Solubility 
5.765g/L(24 ºC)
Stability:
Hygroscopic
InChI
InChI=1S/C4H8N4O2/c9-5-7-1-2-8(6-10)4-3-7/h1-4H2
InChIKey
WNSYEWGYAFFSSQ-UHFFFAOYSA-N
SMILES
N1(N=O)CCN(N=O)CC1
CAS DataBase Reference
140-79-4
EPA Substance Registry System
Piperazine, 1,4-dinitroso- (140-79-4)
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Safety

Hazardous Substances Data
140-79-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H350May cause cancer

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D480420
Product name
1,4-Dinitrosopiperazine
Packaging
2g
Price
$250
Updated
2021/12/16
TRC
Product number
D480420
Product name
1,4-Dinitrosopiperazine
Packaging
500mg
Price
$105
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22439
Product name
1,4-Dinitrosopiperazine
Packaging
500mg
Price
$115
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22439
Product name
1,4-Dinitrosopiperazine
Packaging
1g
Price
$199.9
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22439
Product name
1,4-Dinitrosopiperazine
Packaging
2g
Price
$363.4
Updated
2021/12/16
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N,N'-DINITROSOPIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, subcutaneous, and intraperitoned routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NNITROSO COMPOUNDS.

in vivo

N,N'-Dinitrosopiperazine (injected into the tail veins; 40 mg/kg; 30 days) inhibits cell motility and invasion, and facilitates NPC metastasis in vivo. From a IHC result, Phospho-LYRIC expression is higher in the metastatic tumors of DNP-treated mice than in those of the untreated control mice[1].

Animal Model:BABL/c nude mice injected with labeled 6-10B cell suspensions (1?×?104?cells) with or without DNP(40 mg/kg)[1]
Dosage:40 mg/kg
Administration:Injected into the tail veins; 30 days
Result:Induced LYRIC phosphorylation at serine 568 associated with NPC metastasis in vivo.

N,N'-DINITROSOPIPERAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N'-DINITROSOPIPERAZINE Suppliers

Canada 1 China 61 Europe 1 France 1 Germany 1 India 4 South Korea 1 Sweden 1 Ukraine 1 United Kingdom 2 United States 6 Global 80
Ramidus AB
Tel
--
Fax
--
Email
hans.holmberg@synthelec.se
Country
Sweden
ProdList
1103
Advantage
30
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View Lastest Price from N,N'-DINITROSOPIPERAZINE manufacturers

Moxin Chemicals
Product
1,4-Dinitrosopiperazine 140-79-4
Price
US $0.00-0.00/mg
Min. Order
1mg
Purity
>95% HPLC
Supply Ability
10000
Release date
2025-04-21
Henan Fengda Chemical Co., Ltd
Product
N,N'-DINITROSOPIPERAZINE 140-79-4
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28

140-79-4, N,N'-DINITROSOPIPERAZINERelated Search:

N-NITROSO-METHYL-ETHYLAMINE N-NITROSODIETHYLAMINE N,N'-DINITROSOPIPERAZINE N-NITROSODIMETHYLAMINE N,N-DINITROPIPERAZINE 1,4-diaminopiperazine hydrate 1-AMINO PIPERAZINE 1-nitrosopiperazine N,N-DIETHYLHYDRAZINE 2-METHYL-1,4-DINITROSOPIPERAZINE 2,3,5,6-Tetramethyl-1,4-dinitrosopiperazine (2R,6R)-2,6-DIMETHYL-1,4-DINITROSOPIPERAZINE 2-NITRO-1,4-DINITROSOPIPERAZINE (2R,5S)-2,5-DIMETHYL-1,4-DINITROSOPIPERAZINE 2,3-DIMETHYL-1,4-DINITROSOPIPERAZINE 1,4-DINITROSOPIPERAZINE-2-CARBOXYLIC ACID (2R,6S)-2,6-DIMETHYL-1,4-DINITROSOPIPERAZINE 2,6-DIMETHYL-1,4-DINITROSOPIPERAZINE

  • N,N'-DINITROSOPIPERAZINE
  • TIMTEC-BB SBB008187
  • 1,4-dinitroso-piperazin
  • Dinitrosopiperazin
  • Dinitrosopiperazine
  • Dnpz
  • NSC 339
  • nsc339
  • USAF do-36
  • usafdo-36
  • 1,4-DINITROSOPIPERAZINE
  • Dinitrosopiperazine: (Piperazine, 1,4-dinitroso-)
  • 1,4-dinitrosopiperidine
  • Piperazine Impurity 4
  • Piperazine, 1,4-dinitroso-
  • N- Nitrosopiperazine DIMER
  • 140-79-4---N,N'-DINITROSOPIPERAZINE
  • N,N-Dinitroso-Piperazin
  • Piperazine Impurity 24
  • N,N'-Dinitrosopiperazine (DMP)
  • 1,4-Dinitrosopiperazine in acetonitrile
  • Rifapentine Impurity 7
  • N,N'-Dinitrosopiperazine (DMP)
  • N,N'-Dinitrosopiperazine Solution (1 mL (1 mg/mL)) in Methanol : 1,4-Dinitrosopiperazine
  • 140-79-4
  • C4H8N2NO2
  • Heterocycles
  • Mutagenesis Research Chemicals