2,5-Dibromoterephthalic acid
Application- Product Name
- 2,5-Dibromoterephthalic acid
- CAS No.
- 13731-82-3
- Chemical Name
- 2,5-Dibromoterephthalic acid
- Synonyms
- JACS-13731-82-3;2,5-Dibromoterephtha;2,5-Dibromterephthalsure;2,5-DibromoterephthalicAci;2,5-DIBROMOTEREPHTALIC ACID;2,5-DIBROMOTEREPHTHALIC ACID;2,5-dibromotetrephthalic acid;2,5-DibromoterephthalicAcid>2,5-dibromo-4-benzenedicarboxylicacid;2,5-Dibromo-1,4-PhenyldicarboxylicAcid
- CBNumber
- CB0423720
- Molecular Formula
- C8H4Br2O4
- Formula Weight
- 323.92
- MOL File
- 13731-82-3.mol
2,5-Dibromoterephthalic acid Property
- Melting point:
- 320-325°C
- Boiling point:
- 445.0±45.0 °C(Predicted)
- Density
- 2.205±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 1.75±0.10(Predicted)
- color
- White to Almost white
- InChIKey
- VUTICWRXMKBOSF-UHFFFAOYSA-N
- CAS DataBase Reference
- 13731-82-3(CAS DataBase Reference)
- EPA Substance Registry System
- 1,4-Benzenedicarboxylic acid, 2,5-dibromo- (13731-82-3)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-36
- HS Code
- 2917399590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D3994
- Product name
- 2,5-Dibromoterephthalic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $70
- Updated
- 2025/07/31
- Product number
- D3994
- Product name
- 2,5-Dibromoterephthalic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $275
- Updated
- 2025/07/31
- Product number
- D426195
- Product name
- 2,5-Dibromoterephthalic Acid
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- D426195
- Product name
- 2,5-Dibromoterephthalic Acid
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FD70813
- Product name
- 2,5-Dibromoterephthalic acid
- Packaging
- 25g
- Price
- $55
- Updated
- 2021/12/16
2,5-Dibromoterephthalic acid Chemical Properties,Usage,Production
Application
2,5-Dibromoterephthalic acid is an organic synthesis intermediate and a pharmaceutical intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis.
Chemical Properties
white crystalline powder
Synthesis
1074-24-4
13731-82-3
This embodiment describes a process for the synthesis of 2,5-dibromoterephthalic acid using 2,5-dibromo-1,4-dimethylbenzene as a starting material. NaBr (5 mmol) in 500 g of 97% acetic acid solution. The mixture was stirred at a constant rate using a gas dispersion stirrer to optimize the gas mixing, and then the mixture was heated to 150 °C and maintained for 2 h (this stage is labeled as "TI" in Table 1), after which it was warmed up to 180 °C to continue the reaction for 4 h (this stage is labeled as "T -2"). During the heating process, air is continuously vented at 400 psig (2.76 MPa) back pressure. At the end of the reaction, the pressure was released and the reactor was cooled to 50°C. The product was drained and the reactor was rinsed with 50 g of acetic acid in two passes to collect the residual product. The white solid product was collected by diafiltration, washed with water, and dried under vacuum to yield 310 g (84% yield) of 2,5-dibromoterephthalic acid as a white solid with 99% purity as determined by 1H NMR. Examples 2-5 explored the effect of different reaction stages, time and temperature conditions on the net yield and purity of 2,5-dibromoterephthalic acid, all following the procedure of Example 1, with the specific conditions adjusted as shown in Table 1. In all cases, the resulting 2,5-dibromoterephthalic acid was a white solid of not less than 99 mol% purity.
References
[1] Patent: US2010/168444, 2010, A1. Location in patent: Page/Page column 4-8
[2] Bulletin of the Korean Chemical Society, 2011, vol. 32, # 5, p. 1781 - 1783
[3] Patent: WO2008/82501, 2008, A1. Location in patent: Page/Page column 15-16
[4] Journal of the American Chemical Society, 2014, vol. 136, # 43, p. 15414 - 15421
[5] Chemical Communications, 2010, vol. 46, # 35, p. 6503 - 6505
2,5-Dibromoterephthalic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2,5-Dibromoterephthalic acid Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 2,5-Dibromoterephthalic acid manufacturers
- Product
- 2,5-Dibromoterephthalic Acid 13731-82-3
- Price
- US $30.00-2.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- g-kg-tons,free sample is available
- Release date
- 2024-01-03
- Product
- 2,5-Dibromoterephthalic acid 13731-82-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2'-Amino-1,1':4',1''-terphenyl-4,4''-dicarboxylic acid 13731-82-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25