4-Amino-3,5-dichloroacetophenone
Description Storage- Product Name
- 4-Amino-3,5-dichloroacetophenone
- CAS No.
- 37148-48-4
- Chemical Name
- 4-Amino-3,5-dichloroacetophenone
- Synonyms
- 1-(4-amino-3,5-dichlorophenyl)ethan-1-one;1-(4-Amino-3,5-dichlorophenyl)-ethanone, 3,5-Dichloro-4-aminoacetophenone;5-dichlorophenyl)-;TIMTEC-BB SBB003511;3,5-dichloro-4-amino;Clenbuterol EP Impurity C;4-ACETYL-2,6-DICHLOROANILINE;3, 5-dichloro-4-aminophenone;4-Anubi3,5-dichloroacetophenone;4-AMINO-3,5-DICHLOROACETOPHENONE
- CBNumber
- CB0423917
- Molecular Formula
- C8H7Cl2NO
- Formula Weight
- 204.05
- MOL File
- 37148-48-4.mol
4-Amino-3,5-dichloroacetophenone Property
- Melting point:
- 162-166 °C(lit.)
- Boiling point:
- 351.5±42.0 °C(Predicted)
- Density
- 1.2748 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -1.72±0.10(Predicted)
- color
- Light Tan to Brown
- InChI
- InChI=1S/C8H7Cl2NO/c1-4(12)5-2-6(9)8(11)7(10)3-5/h2-3H,11H2,1H3
- InChIKey
- JLPKZJDZXIKSCP-UHFFFAOYSA-N
- SMILES
- C(=O)(C1=CC(Cl)=C(N)C(Cl)=C1)C
- CAS DataBase Reference
- 37148-48-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HS Code
- 29223990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 536148
- Product name
- 4′-Amino-3′,5′-dichloroacetophenone
- Purity
- 97%
- Packaging
- 25g
- Price
- $109.2
- Updated
- 2024/03/01
- Product number
- A1967
- Product name
- 4'-Amino-3',5'-dichloroacetophenone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $44
- Updated
- 2024/03/01
- Product number
- A1967
- Product name
- 4'-Amino-3',5'-dichloroacetophenone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $125
- Updated
- 2024/03/01
- Product number
- A604690
- Product name
- 1-(4-Amino-3,5-dichlorophenyl)-2-ethanone
- Packaging
- 10g
- Price
- $230
- Updated
- 2021/12/16
- Product number
- FA17498
- Product name
- 1-(4-Amino-3,5-dichloro-phenyl)-2-ethanone
- Packaging
- 100g
- Price
- $110
- Updated
- 2021/12/16
4-Amino-3,5-dichloroacetophenone Chemical Properties,Usage,Production
Description
4-Amino-3,5-dichloroacetophenone is an intermediate in the synthesis of the antitussive and antiasthmatic drug gramtin.
Storage
4-Amino-3,5-dichloroacetophenone should be stored in a cool, dry place
in a small, well filled, well-closed container, protected from light.
When a partially filled container is used, the air should be replaced by
nitrogen or another inert gas.
4-Amino-3,5-dichloroacetophenone
oxidizes on exposure to air, resulting in an increase in the peroxide
value.
Chemical Properties
4-Amino-3,5-dichloroacetophenone is a white to light yellow crystal powder. Insoluble in cold water, slightly soluble in hot water.
Uses
4-Amino-3,5-dichloroacetophenone is used to synthesize the drug Clenbuterol. Clenbuterol is a steroid-like chemical that was initially developed to treat asthma in horses, working by relaxing the airways in the animals'lungs.
Preparation
4-Amino-3,5-dichloroacetophenone was synthesized by chlorination of 4-aminoacetophenone. Add 4-aminoacetophenone and acetic acid (80%) into the reaction pot, stir and dissolve, quickly add chlorine-containing glacial acetic acid solution, the temperature of the addition is 5°C. After the addition is completed, immediately put into ice water to precipitate, filter, and wash with water to obtain the crude product. Recrystallize with ethanol to obtain the finished product of 4-Amino-3,5-dichloroacetophenone.
Application
4-Amino-3,5-dichloroacetophenone is a compound useful in organic synthesis.
Application
4-Amino-3,5-dichloroacetophenone has active chemical properties and has been widely used in industrial chemistry, agricultural chemistry, and pharmaceutical chemistry. As a selective oxidant and green coupling reagent, it participates in a variety of oxidation reactions, rearrangement reactions, and amination reactions. In industry, it can also be used as a raw material for the synthesis of drugs, disinfectants, dyes, food seasonings, adhesives, explosives, etc.
4-Amino-3,5-dichloroacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
4-Amino-3,5-dichloroacetophenone Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
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- Fax
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- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 4-Amino-3,5-dichloroacetophenone manufacturers
- Product
- 4-Amino-3,5-dichloroacetophenone 37148-48-4
- Price
- US $10.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-03-26
- Product
- 4'-Amino-3' 5'-Dichloroacetophenone 37148-48-4
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 10000
- Release date
- 2023-04-04
- Product
- 4-Amino-3,5-dichloroacetophenone 37148-48-4
- Price
- US $0.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 20
- Release date
- 2024-04-15