ZOPICLONE N-OXIDE

Product Name: ZOPICLONE N-OXIDE
CAS No.: 43200-96-0
Chemical Name: ZOPICLONE N-OXIDE
Synonyms: RP 2975;RP 29753;ZOPICLONE N-OXIDE;Eszopiclone IMpurity A;Zopiclone EP Impurity A;Zopiclone-N-oxide solution;Eszopiclone Related CoMpound A;Zopiclone N-Oxide Solution, 100ppm;Eszopiclone USP Related Compound A;Zopiclone Impurity A (Zopiclone N-Oxide)
CBNumber: CB0428563
Molecular Formula: C17H17ClN6O4
Formula Weight: 404.81
MOL File: 43200-96-0.mol

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ZOPICLONE N-OXIDE Property

Melting point:: >140°C (dec.)
Flash point:: 9℃
storage temp.: 2-8°C
solubility: Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka: 4.92±0.20(Predicted)
color: White to Light Brown

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45
RIDADR: UN1230 - class 3 - PG 2 - Methanol
WGK Germany: 1
HS Code: 2933790002

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Z-013
Product name: Zopiclone-N-oxide solution
Purity: 100?μg/mL (Methanol with 1% 1 M HCl), ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $158
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1255861
Product name: Zopiclone-N-oxide solution
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 10mg
Price: $596
Updated: 2024/03/01

Sigma-Aldrich

Product number: Z3001000
Product name: Zopiclone oxide
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: z3001000
Price: $153
Updated: 2024/03/01

Usbiological

Product number: 292130
Product name: Zopiclone N-oxide
Packaging: 2mg
Price: $425
Updated: 2021/12/16

Usbiological

Product number: Z0810-02
Product name: Zopiclone N-Oxide
Packaging: 5mg
Price: $460
Updated: 2021/12/16

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ZOPICLONE N-OXIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White to Pale Beige Solid

Uses

A metabolite of Zopiclone

Uses

Eszopiclone impurity A.

General Description

Zopiclone N-oxide is a primary, active metabolite of zopiclone in urine as well as a major pharmaceutical impurity of zopiclone known as eszopiclone impurity A. The parent drug, zopiclone, is a non-benzodiazepine hypnotic sold under the trade names Imovane^?and ZImovane^?and is used in the treatment of insomnia.

ZOPICLONE N-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ZOPICLONE N-OXIDE Suppliers

Canada 2 China 53 India 4 United Kingdom 1 United States 9 Global 69

Changzhou Xianglong Pharmaceutical Technology Co., LTD

Tel: 18661161657
Email: yaoxiangqiu2021@163.com
Country: China
ProdList: 10066
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 336
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1958
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7715
Advantage: 55

43200-96-0, ZOPICLONE N-OXIDERelated Search:

6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one Eszopiclone Levetiracetam impurity 1 N-(5-Chloro-2-pyridinyl)-2-pyrazinecarboxaMide (Zopiclone IMpurity) 2-Amino-5-chloropyridine Zopiclone RP 48497 (Eszopiclone Impurity C) N-(5-Chloro-2-pyridinyl)-3-(hydroxyMethyl)-2-pyrazinecarboxaMide ZOPICLONE OXIDE Zopiclone iMpurity (5-(Chloropyridine-2-yl-carbaMoyl)pyrazine) Zopiclone iMpurity A N-Boc-N-desmethyl Zopiclone 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI) Zopiclone Impurity 10 Zopiclone Impurity 18 Zopiclone Impurity 3 Deschloro-Zopiclone

RP 2975

1-Piperazine-carboxylic Acid 4-Methyl-4-oxide 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester

Zopiclone N-Oxide(Mixture of diastereomers)

RP 29753

Zopiclone N-Oxide (Eszopiclone Impurity A)(Mixture of Diastereomers)

Zopiclone N-Oxide (Eszopiclone Impurity A)

ZOPICLONE N-OXIDE

4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester 4-oxide

Eszopiclone IMpurity A

Eszopiclone Related CoMpound A

(5RS)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate 4-oxide

Dexzopiclone impurity A (zopiclone nitrogen oxide)

Zopiclone N-Oxide Solution, 100ppm

Zopiclone-N-oxide solution

Zopiclone Impurity A (Zopiclone N-Oxide)

4-(((6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl)oxy)carbonyl)-1-methylpiperazine1-oxide

Zopiclone Impurity 1 (Zopiclone EP Impurity A)

Zopiclone EP Impurity A (Zopiclone N-Oxide)

Zopiclone EP Impurity A

[6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methyl-4-oxidopiperazin-4-ium-1-carboxylate

6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate 4-oxide

1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester, 4-oxide

6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]...

Zopiclone N-OxideQ: What is Zopiclone N-Oxide Q: What is the CAS Number of Zopiclone N-Oxide Q: What is the storage condition of Zopiclone N-Oxide Q: What are the applications of Zopiclone N-Oxide

Eszopiclone Related Compound A (6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo [3,4,b] pyraz (1255861)

Eszopiclone USP Related Compound A

43200-96-0

C17H17ClN6O4

Isotopically Labeled Pharmaceutical Reference Standard

Heterocycles

Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals