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4-CHLOROISATIN

Product Name
4-CHLOROISATIN
CAS No.
6344-05-4
Chemical Name
4-CHLOROISATIN
Synonyms
4-CHLOROISATIN;BUTTPARK 50\07-90;4-CHLOROINDOLE-2,3-DIONE;4-CHLORO-2,3-INDOLINEDIONE;4-Chloro-(1H)-indole-2,3-dione;1H-Indole-2,3-dione, 4-chloro-;4-Chloro-2,3-dihydro-1H-indole-2,3-dione;4-chloro-1H-indole-2,3-dione(SALTDATA: FREE);4-Chloroindole-2,3-dione 4-Chloro-2,3-indolinedione
CBNumber
CB0434508
Molecular Formula
C8H4ClNO2
Formula Weight
181.58
MOL File
6344-05-4.mol
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4-CHLOROISATIN Property

Melting point:
258 °C
Density 
1.519±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Dimethylformamide
form 
powder to crystal
pka
9.44±0.20(Predicted)
color 
Light yellow to Brown
CAS DataBase Reference
6344-05-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C1870
Product name
4-Chloroisatin
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$26
Updated
2025/07/31
TCI Chemical
Product number
C1870
Product name
4-Chloroisatin
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$80
Updated
2025/07/31
TRC
Product number
C428602
Product name
4-Chloroisatin
Packaging
1g
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC38479
Product name
4-Chloroisatin
Packaging
25g
Price
$53.75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC38479
Product name
4-Chloroisatin
Packaging
450g
Price
$405
Updated
2021/12/16
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4-CHLOROISATIN Chemical Properties,Usage,Production

Chemical Properties

Orange powder

Uses

4-Chloroisatin is an isatic acid derivative that performs a plant growth-regulating activity. Isatin compounds also performs selective inhibitory functions against carboxylesterases.

Synthesis

302-17-0

108-42-9

6344-05-4

Chloral hydrate (8.93 g, 0.054 mol), anhydrous sodium sulfate (130 g, 0.40 mol), m-chloroaniline (0.05 mol), hydroxylammonium chloride (10.98 g, 0.158 mol), and concentrated hydrochloric acid (43 mL) were added to 120 mL of water in sequence. The resulting suspension was heated to 90 °C, maintained for 5 minutes and cooled to room temperature. The reaction mixture was filtered and washed with water (2 x 20 mL) to obtain the crude product. The crude product was added in batches to a 250 mL three-necked flask pre-filled with concentrated sulfuric acid (32.6 mL) and preheated to 65 °C, after which the mixture was heated to 80 °C and maintained for 20 minutes. After completion of the reaction, the solution was cooled to room temperature and slowly poured into 500 g of ice water with vigorous stirring for 4 hours. The intermediate 4-chloroindoline-2,3-dione was isolated by filtration, washed with water and recrystallized from ethanol in a final yield of 25.7% to 73.2%.

References

[1] Chinese Chemical Letters, 2013, vol. 24, # 10, p. 929 - 933

4-CHLOROISATIN Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLOROISATIN Suppliers

Americas 1 China 116 Europe 1 Germany 2 India 2 Japan 2 United Kingdom 5 United States 18 Global 147
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from 4-CHLOROISATIN manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-Chloroisatin 6344-05-4
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-08-29
Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
4-Chloroisatin 6344-05-4
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-08-20
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-CHLOROISATIN 6344-05-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

6344-05-4, 4-CHLOROISATINRelated Search:

4-CHLOROISATIN 7-CHLOROISATIN 4,7-Dichloroisatin 4-Chloro-7-methylisatin 4,6-DICHLORO-1H-INDOLE-2,3-DIONE 5-CHLOROISATIN/5-CHLORO-2,3-INDOLINEDIONE,5-Chloroisatin ,98%,5-CHLOROISATIN 6-CHLOROISATIN 4-Chloroindole 4,5-DICHLORO-1H-INDOLE-2,3-DIONE 4-CHLORO-7-METHOXY ISATIN 4-CHLORO-5-METHYLISATIN CHLOROISATIN 2-chloroisatin 5-CHLOROISATIN 100MG [R] 4-chloro-7-nitro-2,3-dihydro-1H-indole-2,3-dione BUTTPARK 50\07-80 4-CHLORO-7-FLUORO-1H-INDOLE-2,3-DIONE 4-CHLORO-5-ETHYLISATIN

  • 4-CHLORO-2,3-INDOLINEDIONE
  • 4-CHLOROISATIN
  • 4-CHLOROINDOLE-2,3-DIONE
  • 4-Chloro-(1H)-indole-2,3-dione
  • BUTTPARK 50\07-90
  • 4-Chloro-2,3-dihydro-1H-indole-2,3-dione
  • 4-chloro-1H-indole-2,3-dione(SALTDATA: FREE)
  • 4-Chloroindole-2,3-dione 4-Chloro-2,3-indolinedione
  • 1H-Indole-2,3-dione, 4-chloro-
  • 6344-05-4
  • 6344-5-4
  • Simple Indoles
  • Indoles
  • Indane/Indanone and Derivatives
  • Indoles
  • Simple Indoles