6-Chloroisatin
- Product Name
- 6-Chloroisatin
- CAS No.
- 6341-92-0
- Chemical Name
- 6-Chloroisatin
- Synonyms
- 6-Chloroisotin;6-CHLOROISATIN;BUTTPARK 50\07-92;6-Chloroisatin >6-Chloroisatin, 97+%;6-CHLOROINDOLE-2,3-DIONE;6-Coroindoline-2,3-dione;6-CHLORO-2,3-INDOLINEDIONE;6-CHLORO ISATINIC ANHYDRIDE;6-CHLORO-1H-INDOLE-2,3-DIONE
- CBNumber
- CB4433488
- Molecular Formula
- C8H4ClNO2
- Formula Weight
- 181.58
- MOL File
- 6341-92-0.mol
6-Chloroisatin Property
- Melting point:
- 262 °C
- Density
- 1.519±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Dimethylformamide
- form
- powder to crystal
- pka
- 8.83±0.20(Predicted)
- color
- Light yellow to Brown
- InChI
- InChI=1S/C8H4ClNO2/c9-4-1-2-5-6(3-4)10-8(12)7(5)11/h1-3H,(H,10,11,12)
- InChIKey
- RVXLBLSGEPQBIO-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC(Cl)=C2)C(=O)C1=O
- CAS DataBase Reference
- 6341-92-0(CAS DataBase Reference)
Safety
- HS Code
- 2933790090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1871
- Product name
- 6-Chloroisatin
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $61
- Updated
- 2025/07/31
- Product number
- C1871
- Product name
- 6-Chloroisatin
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $242
- Updated
- 2025/07/31
- Product number
- C428808
- Product name
- 6-Chloroisatin
- Packaging
- 10mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- A745
- Product name
- 6-Chloroisatin
- Packaging
- 5g
- Price
- $27
- Updated
- 2021/12/16
- Product number
- OR40689
- Product name
- 6-Chloroisatin
- Purity
- 97+%
- Packaging
- 25g
- Price
- $103
- Updated
- 2021/12/16
6-Chloroisatin Chemical Properties,Usage,Production
Chemical Properties
Orange powder
Uses
6-Chloroisatin can be used as potential apoptosis inducer in non-small lung cancer AS49 cells.
Synthesis
215959-30-1
6341-92-0
Step 2: 6-Chloroindirubin 3,3-dibromo-6-chloro-1,3-dihydro-indol-2-one (21.34 g, 59.7 mmol) was suspended in a 4:1 (v:v) solvent mixture of methanol and water (172 mL of methanol and 43 mL of water) and heated and refluxed for 19 hours. Upon completion of the reaction, the mixture was cooled in an ice bath and subsequently filtered. The resulting red solid was washed once with cold methanol and dried to give 6-chloroindole-2,3-dione (10.49 g, 88% yield). The product was confirmed to be structurally consistent by NMR hydrogen spectroscopy (400 MHz, DMSO-d6). Mass spectrometry analysis (API-ES+) showed m/z 182/184 [M+H]+, consistent with a characteristic peak containing one chlorine atom.
References
[1] Patent: US2005/250798, 2005, A1. Location in patent: Page/Page column 26
[2] Tetrahedron Letters, 1998, vol. 39, # 42, p. 7679 - 7682
[3] Tetrahedron Letters, 2002, vol. 43, # 26, p. 4671 - 4673
6-Chloroisatin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Chloroisatin manufacturers
- Product
- 6-Chloroisatin 6341-92-0
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-29
- Product
- 6-Chloroisatin 6341-92-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-08-20
- Product
- 6-Chloroisatin 6341-92-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-31