ChemicalBook > CAS DataBase List > Boc-L-Tyr(tBu)-OH

Boc-L-Tyr(tBu)-OH

Product Name
Boc-L-Tyr(tBu)-OH
CAS No.
47375-34-8
Chemical Name
Boc-L-Tyr(tBu)-OH
Synonyms
BOC-TYR(TBU)-OH;Boc-Tyr(tBu);BOC-L-TYR(TBU)-OH;BOC-TYR(BUT)-OH;Boc-Tyr(tBul)-OH;TIMTEC-BB SBB006926;BOC-TYROSINE(TBU)-OH;Boc-Tyr(tBu)-OH 100g;Boc-Tyr(tBu)-OH, 99.0%;BOC-O-T-BUTYL-L-TYROSINE
CBNumber
CB0434634
Molecular Formula
C18H27NO5
Formula Weight
337.41
MOL File
47375-34-8.mol
More
Less

Boc-L-Tyr(tBu)-OH Property

Melting point:
113-118 °C
alpha 
-15 º (C=1% IN DMF)
Boiling point:
484.0±40.0 °C(Predicted)
Density 
1.116±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder to crystal
pka
3.00±0.10(Predicted)
color 
White to Almost white
optical activity
[α]20/D 15.0±1.0°, c = 1% in DMF
Water Solubility 
Soluble in DMF. Insoluble in water.
BRN 
4327336
InChI
InChI=1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1
InChIKey
ZEQLLMOXFVKKCN-AWEZNQCLSA-N
SMILES
C(O)(=O)[C@H](CC1=CC=C(OC(C)(C)C)C=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference
47375-34-8(CAS DataBase Reference)
More
Less

Safety

WGK Germany 
3
HS Code 
29242990
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.53023
Product name
Boc-Tyr(tBu)-OH
Purity
Novabiochem?
Packaging
5G
Price
$194
Updated
2024/03/01
Sigma-Aldrich
Product number
8.53023
Product name
Boc-Tyr(tBu)-OH
Purity
Novabiochem?
Packaging
25g
Price
$764
Updated
2024/03/01
TCI Chemical
Product number
B3485
Product name
N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
B3485
Product name
N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$86
Updated
2024/03/01
Alfa Aesar
Product number
H62801
Product name
N-Boc-O-tert-butyl-L-tyrosine, 98%
Packaging
5g
Price
$122.65
Updated
2024/03/01
More
Less

Boc-L-Tyr(tBu)-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

N-Boc-O-tert-butyl-L-tyrosine (Boc-L-Tyr(tBu)-OH) is used as pharmaceutical intermediate.

Application

Boc-Tyr(tBu)-OH is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. This compound could be used as a starting material to synthesize TPE-Tyr. TPE-Tyr can undergo covalent crosslinking via the formation of dityrosine linkages by exploiting horseradish peroxidase (HRP)-catalyzed phenol polymerization in the presence of H2O2, thereby activating the AIE process and switching on fluorescence emission of TPE core motif[1].

Synthesis

O-tert-butyl-L-tyrosine (2.00 g, 8.42 mmol, 1.0 equiv.) and di-tert-butyl dicarbonate (2.20 g, 10.10 mmol, 1.2 equiv.) were dissolved in a mixture of THF (15 mL) and NaOH (1 N, 30 mL) and stirred at room temperature for 10 h. THF was removed under reduced pressure, and the pH of residual solution was adjusted to 3.0 with dilute hydrochloric acid and the crude product was extracted by ethyl acetate. The combined organic phases was washed with saturated brine (pH 3.0) and dried over anhydrous Na2SO4. The organic solvent was removed under reduced pressure and dried in a vacuum oven at room temperature overnight, affording (N-Boc-O-tert-butyl)-L-Tyr (Boc-O-tert-butyl-L-tyrosine) as a yellowish solid (2.64 g, 93%)[1].

References

[1] Wang X, et al. Highly Selective Fluorogenic Multianalyte Biosensors Constructed via Enzyme-Catalyzed Coupling and Aggregation-Induced Emission. Journal of the American Chemical Society, 2014; 136: 9890–9893.

Boc-L-Tyr(tBu)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Boc-L-Tyr(tBu)-OH Suppliers

Americas 1 China 183 Europe 3 Germany 5 India 3 Japan 3 Switzerland 2 United Kingdom 9 United States 30 Global 239
Chengdu Tachem Co., Ltd
Tel
028-61682518; 19983060238
Email
sales@tachem.cn
Country
China
ProdList
103
Advantage
58
Sichuan HongRi Pharma-Tech Co., Ltd
Tel
18054780191
Fax
0838-2822568
Email
551604319@qq.com
Country
China
ProdList
2037
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019
Email
boyu2024@163.com
Country
China
ProdList
2734
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Sichuan Tongsheng Amino acids Co.,Ltd.
Tel
0838-2809458 13350585791
Fax
+86-838-2274207
Email
pharm@biots.cn
Country
China
ProdList
333
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9512
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9810
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9894
Advantage
55
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Sichuan Ampebiochem Co., Ltd.
Tel
028-65294243
Fax
028-85275169
Email
sales@ampebiochem.com
Country
China
ProdList
1006
Advantage
58
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2045
Advantage
56
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4613
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Shandong Juntai Pharmaceutical Co., LTD.
Tel
18615688519
Fax
0531-66958526
Email
sales@h2opharm.com
Country
China
ProdList
162
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7979
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8264
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-025-58361106-805-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9980
Advantage
55
Sichuan jiayinglai technology CO.,LTD
Tel
028-88457210 18123311397
Fax
QQ3213375147
Email
anna@enlaibio.com
Country
China
ProdList
2294
Advantage
55
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
More
Less

View Lastest Price from Boc-L-Tyr(tBu)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-L-Tyr(tBu)-OH 47375-34-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-27
Zhuozhou Wenxi import and Export Co., Ltd
Product
Boc-O-tert-butyl-L-tyrosine 47375-34-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
Boc-O-tert-butyl-L-tyrosine 47375-34-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19

47375-34-8, Boc-L-Tyr(tBu)-OHRelated Search:

tert-Butanol tert-Butyl hydroperoxide tert-Butyl methyl ether BUTYL OLEATE 4-tert-Butylcatechol L-Tyrosine Cyhalofop-butyl 4-tert-Butylphenol Boc-Aib-OH Boc-D-Tyr-OH tert-Butyldimethylsilyl chloride Buprofezin Methyl 4-tert-butylbenzoate TYROSINASE Dibutyl phthalate BOC-GLY-LEU-OH Boc-Tyr(Me)-OH O-METHYL-D-TYROSINE

  • (2S)-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
  • (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(tert-butoxy)phenyl]propanoic acid
  • Boc-Tyr(tBu)-OH, 99.0%
  • BOC-L-TYR(TBU)-OH
  • BOC-O-T-BUTYL-L-TYROSINE
  • BOC-O-TERT-BUTYL-L-TYROSINE
  • BOC-TYR(TBU)-OH
  • BOC-TYROSINE(TBU)-OH
  • BOC-TYR(BUT)-OH
  • TIMTEC-BB SBB006926
  • N-ALPHA-T-BOC-O-T-BUTYL-L-TYROSINE
  • N-ALPHA-TERT-BUTYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE
  • N-ALPHA-T-BUTOXYCARBONYL-O-T-BUTYL-L-TYROSINE
  • N-tert-Butoxycarbonyl-O-tert-butyl-L-tyrosine
  • Boc-Tyr(tBul)-OH
  • N-ALPHA-T-BUTYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE
  • (S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid
  • Boc-L-tyrosine beta-tert-butyl ester
  • N-Boc-O-tert-butyl-L-tyrosine Boc-Tyr(tBu)-OH
  • (S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)aMino)propanoic acid
  • N-Boc-O-tert-butyl-L-tyrosine, 98%
  • Boc-Tyr(tBu)-OH 100g
  • (S)-2-(Boc-amino)-3-(4-tert-butoxyphenyl)propionic acid
  • Boc-O-tert-butyl-L-tyrosine≥ 99% (HPLC)
  • (Tert-Butoxy)Carbonyl Tyr(tBu)-OH
  • Boc-Tyr(tBu)
  • N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine &gt
  • L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-
  • Boc-O-tert-butyl-L-tyrosine USP/EP/BP
  • (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
  • BOC-0-tert-butyl-L-tyrosine
  • 47375-34-8
  • CH33COC6H4CH2CHCOOHNHCOOCCH33
  • C18H27NO5
  • CARBOXYLIC ACID
  • Peptide Synthesis
  • Specialty Synthesis
  • Tyrosine
  • Amino Acid Derivatives
  • Boc-Amino Acids and Derivative
  • Boc-Amino acid series
  • Amino Acids