IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE
Description Source Background- Product Name
- IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE
- Chemical Name
- IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE
- Synonyms
- MOUSE IL-22;IL-22 MOUSE;MURINE IL-22;IL-TIF MOUSE;MURINE IL-TIF;MOUSE INTERLEUKIN 22;INTERLEUKIN-22 MOUSE;MURINE INTERLEUKIN-22;Interleukin-22 from mouse;IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE
- CBNumber
- CB0442279
- Formula Weight
- 0
- MOL File
- Mol file
IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE Property
- storage temp.
- −20°C
- form
- lyophilized powder
Safety
- WGK Germany
- 3
IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE Chemical Properties,Usage,Production
Description
Interleukin-22 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 147 amino acids and having a molecular mass of 16.7 kDa.
The Murine IL-22 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Interleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acids signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with human IL-22 and IL-10, respectively. IL-22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R? (previously known as CRF2-4), belonging to the class II cytokine receptor family.
IL-10-RELATED T CELL-DERIVED INDUCIBLE FACTOR MOUSE Preparation Products And Raw materials
Raw materials
Preparation Products
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