ChemicalBook > CAS DataBase List > 6-BROMO-2-QUINAZOLINAMINE

6-BROMO-2-QUINAZOLINAMINE

Product Name: 6-BROMO-2-QUINAZOLINAMINE
CAS No.: 190273-89-3
Chemical Name: 6-BROMO-2-QUINAZOLINAMINE
Synonyms: 6-BROMOQUINAZOLIN-2-AMINE;6-BROMO-2-QUINAZOLINAMINE;2-AMINO-6-BROMOQUINAZOLINE;6-Bromo-2-amino-quinazoline;6-Bromoquinazolin-2-ylamine;2-Quinazolinamine, 6-bromo-
CBNumber: CB0442527
Molecular Formula: C8H6BrN3
Formula Weight: 224.06
MOL File: 190273-89-3.mol

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6-BROMO-2-QUINAZOLINAMINE Property

Boiling point:: 425.3±37.0 °C(Predicted)
Density: 1.744±0.06 g/cm3(Predicted)
storage temp.: Room temperature.
pka: 4.94±0.26(Predicted)
Appearance: Light yellow to brown Solid
InChI: InChI=1S/C8H6BrN3/c9-6-1-2-7-5(3-6)4-11-8(10)12-7/h1-4H,(H2,10,11,12)
InChIKey: IJXKEDDKGGBSBX-UHFFFAOYSA-N
SMILES: N1=C2C(C=C(Br)C=C2)=CN=C1N

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A595090
Product name: 2-Amino-6-bromoquinazoline
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: A595090
Product name: 2-Amino-6-bromoquinazoline
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42042
Product name: 6-Bromo-2-quinazolinamine
Packaging: 100mg
Price: $60
Updated: 2021/12/16

BroadPharm

Product number: BP-20077
Product name: 6-bromoquinazolin-2-amine
Purity: 95%
Packaging: 250mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42042
Product name: 6-Bromo-2-quinazolinamine
Packaging: 250mg
Price: $100
Updated: 2021/12/16

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6-BROMO-2-QUINAZOLINAMINE Chemical Properties,Usage,Production

Synthesis

593-85-1

93777-26-5

190273-89-3

5-Bromo-2-fluorobenzaldehyde (10 g, 49.2 mmol) and guanidine carbonate (13.3 g, 74 mmol) were dissolved in N,N-dimethylacetamide (50 mL). The reaction mixture was heated to reflux temperature with continuous stirring for 5 hours. Upon completion of the reaction, it was cooled to room temperature, water (120 mL) was added and stirring was continued for 2 hours at room temperature. The resulting 6-bromo-2-quinazolinamine was collected by filtration and subsequently dried under vacuum to give the final product (5.0 g, 60% yield).

References

[1] Patent: WO2017/46739, 2017, A1. Location in patent: Page/Page column 49
[2] European Journal of Medicinal Chemistry, 2017, vol. 141, p. 506 - 518
[3] Journal of Organic Chemistry, 2006, vol. 71, # 10, p. 3959 - 3962
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 19, p. 5671 - 5686
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 11, p. 3065 - 3068

6-BROMO-2-QUINAZOLINAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-BROMO-2-QUINAZOLINAMINE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 6-BROMO-2-QUINAZOLINAMINE 190273-89-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 2000
Release date: 2025-09-04

Shaanxi Dideu New Materials Co. Ltd

Product: 6-BROMO-2-QUINAZOLINAMINE 190273-89-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-11

Henan Fengda Chemical Co., Ltd

Product: 6-Bromoquinazolin-2-amine 190273-89-3
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

190273-89-3, 6-BROMO-2-QUINAZOLINAMINERelated Search:

METHYL 6-BROMOQUINOLINE-2-CARBOXYLATE 6-BROMO-2-FLUORO-3-METHOXYPYRIDINE 6-BROMO-2-PHENYL-1H-IMIDAZO[4,5-B]PYRIDINE Methyl-6-bromopyrazine-2-carboxylate 4-Amino-6-bromo-2-methylpyrimidine 6-BROMO-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLIC ACID 6-Bromoquinoline-2-carboxylic acid 6-BroMo-2-fluoro-pyridin-3-aMine 6-Bromo-2-fluoro-3-hydroxypyridine Tiotropium bromide 6-BROMO-2-QUINAZOLINAMINE 6-Bromoquinolin-2-amine 6-BROMO-N,N-DIMETHYL-2-QUINAZOLINAMINE 6-Bromo-quinazoline-2,4-diamine 4-[(6-BROMO-4-PHENYLQUINAZOLIN-2-YL)AMINO]BENZOIC ACID 1-(4-Amino-6-bromo-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hyd rochloride 3-[(6-BROMO-4-PHENYLQUINAZOLIN-2-YL)AMINO]BENZOIC ACID 1-(4-Amino-6,8-dibromo-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride

2-AMINO-6-BROMOQUINAZOLINE

6-BROMO-2-QUINAZOLINAMINE

6-BROMOQUINAZOLIN-2-AMINE

2-Quinazolinamine, 6-bromo-

6-Bromoquinazolin-2-ylamine

6-Bromo-2-amino-quinazoline

190273-89-3

API intermediates