(S)-(+)-TETRAHYDROFURFURYL ALCOHOL

Product Name: (S)-(+)-TETRAHYDROFURFURYL ALCOHOL
CAS No.: 57203-01-7
Chemical Name: (S)-(+)-TETRAHYDROFURFURYL ALCOHOL
Synonyms: 102205;(2S)-oxolan-2-yl]methanol;(S)-TETRAHYDROFURFURYLALCOHOL;(S)-(+)-TETRAHYDROFURFURYL ALCOHOL;2-FuranMethanol, tetrahydro-, (2S)-;(R)-(-)-2-(Hydroxymethyl)tetrahydrofuran;(R)-(-)-2-(Hydroxymethyl)tetrahydrofurane;(2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran;(S)-(+)-TETRAHYDROFURFURYL ALCOHOL ISO 9001：2015 REACH;(2S)-(+)-(Tetrahydrofur-2-yl)methanol, (S)-(+)-Tetrahydrofurfuryl alcohol
CBNumber: CB0448756
Molecular Formula: C5H10O2
Formula Weight: 102.13
MOL File: 57203-01-7.mol

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(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Property

Boiling point:: 176.8±8.0 °C(Predicted)
Density: 1.038±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: liquid
pka: 14.44±0.10(Predicted)
color: Clear, colourless
CAS DataBase Reference: 57203-01-7

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Safety

HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T294085
Product name: (S)-(Tetrahydrofuran-2-yl)methanol
Packaging: 250mg
Price: $195
Updated: 2021/12/16

TRC

Product number: T294085
Product name: (S)-(Tetrahydrofuran-2-yl)methanol
Packaging: 500mg
Price: $360
Updated: 2021/12/16

Apolloscientific

Product number: OR40670
Product name: (2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
Purity: 96%
Packaging: 250mg
Price: $93
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2H01-1-04
Product name: (2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
Packaging: 250mg
Price: $103
Updated: 2021/12/16

Apolloscientific

Product number: OR40670
Product name: (2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran
Purity: 96%
Packaging: 1g
Price: $218
Updated: 2021/12/16

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(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Chemical Properties,Usage,Production

Uses

(S)-(Tetrahydrofuran-2-yl)methanol is used during aminopyrrolopyrimidine derivatives preparation and IGF-1R inhibition in tumors.

Synthesis

87392-05-0

97-99-4

Under argon protection, (R)-tetrahydrofuran-2-carboxylic acid (2 g, 17.22 mmol) was dissolved in 20 mL of tetrahydrofuran (THF) and the reaction flask was cooled in an ice bath. Borane-dimethyl sulfide complex (BH3-SMe2, 2M THF solution, 10 mL, 20.0 mmol) was slowly added to the reaction solution over 10 min. After removing the ice bath, the reaction mixture was stirred at room temperature for 1 hour. Subsequently, the reaction mixture was again cooled in an ice bath and methanol was slowly added until no gas escaped. Finally, the reaction solution was concentrated under reduced pressure to afford the target product tetrahydrofurfuryl alcohol as an oil (1 g, 60% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 1.55-1.70 (m, 1H), 1.72-1.98 (m, 3H), 3.35-4.00 (m, 6H).

References

[1] European Journal of Organic Chemistry, 2001, # 23, p. 4537 - 4542
[2] Patent: WO2016/16238, 2016, A1. Location in patent: Page/Page column 184
[3] Patent: WO2017/134188, 2017, A1. Location in patent: Page/Page column 48; 49
[4] Journal of Medicinal Chemistry, 1995, vol. 38, # 15, p. 2830 - 2841
[5] Journal of Organic Chemistry, 1997, vol. 62, # 2, p. 242 - 243

(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(+)-TETRAHYDROFURFURYL ALCOHOL Suppliers

China 58 Germany 2 India 2 Japan 1 United Kingdom 1 United States 6 USA 1 Global 71

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View Lastest Price from (S)-(+)-TETRAHYDROFURFURYL ALCOHOL manufacturers

Career Henan Chemical Co

Product: (S)-(+)-TETRAHYDROFURFURYL ALCOHOL 57203-01-7
Price: US $2.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg, 5kg ,50kg
Release date: 2020-01-08

57203-01-7, (S)-(+)-TETRAHYDROFURFURYL ALCOHOLRelated Search:

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2-FuranMethanol, tetrahydro-, (2S)-

(R)-(-)-2-(Hydroxymethyl)tetrahydrofuran

(R)-(-)-2-(Hydroxymethyl)tetrahydrofurane

(S)-TETRAHYDROFURFURYLALCOHOL

(2S)-(+)-(Tetrahydrofur-2-yl)methanol, (S)-(+)-Tetrahydrofurfuryl alcohol

(2S)-(+)-2-(Hydroxymethyl)tetrahydrofuran

(S)-(+)-TETRAHYDROFURFURYL ALCOHOL

(2S)-oxolan-2-yl]methanol

102205

(S)-(+)-TETRAHYDROFURFURYL ALCOHOL ISO 9001：2015 REACH

57203-01-7

Alcohols, Hydroxy Esters and Derivatives

Chiral Compounds