ChemicalBook > CAS DataBase List > MMP INHIBITOR I

MMP INHIBITOR I

Product Name: MMP INHIBITOR I
CAS No.: 124168-73-6
Chemical Name: MMP INHIBITOR I
Synonyms: FN-439;MMP INHIBITOR I;MMP INHIBITOR 1;METALLOPROTEASE INHIBITOR 1;4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;H-4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;MATRIX METALLOPROTEINASE INHIBITOR I;P-aminobenzoyl-gly-pro-D-leu-D-ala*hydroxamic aci;4-aminobenzoyl-gly-pro-d-leu-d-ala hydroxamic acid;P-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID
CBNumber: CB0456098
Molecular Formula: C23H34N6O6
Formula Weight: 490.55
MOL File: 124168-73-6.mol

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MMP INHIBITOR I Property

Density: 1.288±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: H₂O: 1 mg/mL
pka: 9.34±0.40(Predicted)
form: solid
color: white
Water Solubility: water: 1mg/mL

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 444250
Product name: MMP Inhibitor I
Purity: The MMP Inhibitor I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Packaging: 10MG
Price: $214
Updated: 2025/07/31

Sigma-Aldrich

Product number: A4336
Product name: 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid
Purity: ≥95% (HPLC)
Packaging: 5mg
Price: $278
Updated: 2023/06/20

Chem-Impex

Product number: 32933
Product name: 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
Packaging: 5MG
Price: $72
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA111048
Product name: 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
Packaging: 5mg
Price: $118
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA111048
Product name: 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
Packaging: 10mg
Price: $205
Updated: 2021/12/16

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MMP INHIBITOR I Chemical Properties,Usage,Production

Uses

FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2].

Biological Activity

Collagenase Inhibitor

in vivo

FN-439 significantly decreases neutrophils and macrophages, shows extensive bone formation and active cementogenesis in the periapical region when has a combination with ofloxaci^[2].

References

[1] U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8. DOI:10.1023/a:1006639214618
[2] H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73. DOI:10.1016/S0099-2399(96)80061-6

MMP INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

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MMP INHIBITOR I Suppliers

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124168-73-6, MMP INHIBITOR IRelated Search:

MMP INHIBITOR III KB8301 MATRIX METALLOPROTEINASE INHIBITOR Ilomastat, Liquid (GM6001, MMP Inhibitor, Galardin) MMP INHIBITOR IV GM6001 MMP INHIBITOR MMP Inhibitor Set I MMP INHIBITOR II MATRIX METALLOPROTEINASE INHIBITOR I 98+% N-Benzyl-2-(1-pyrrolidinyl)ethanamine (D-LEU2)-MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING FACTOR procainamide MMP INHIBITOR I

P-aminobenzoyl-gly-pro-D-leu-D-ala*hydroxamic aci

4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH

METALLOPROTEASE INHIBITOR 1

MATRIX METALLOPROTEINASE INHIBITOR I

4-aminobenzoyl-gly-pro-d-leu-d-ala hydroxamic acid

D-AlaninaMide, N-(4-aMinobenzoyl)glycyl-L-prolyl-D-leucyl-N-hydroxy-

4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt

H-4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH

FN-439

MMP INHIBITOR 1

MMP INHIBITOR I

P-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID

4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid >=95% (HPLC)

4-Aminobenzoyl-Gly-Pro-<sc>D</sc>-Leu-<sc>D</sc>-Ala hydroxamic acid

124168-73-6

C23H34N6O6

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Extracellular Matrix

Cytoskeleton and Extracellular Matrix

Metalloproteinase Inhibitors

Inhibitor of human matrix metalloproteinases.