MMP INHIBITOR I
- Product Name
- MMP INHIBITOR I
- CAS No.
- 124168-73-6
- Chemical Name
- MMP INHIBITOR I
- Synonyms
- FN-439;MMP INHIBITOR I;MMP INHIBITOR 1;METALLOPROTEASE INHIBITOR 1;4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;H-4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;MATRIX METALLOPROTEINASE INHIBITOR I;P-aminobenzoyl-gly-pro-D-leu-D-ala*hydroxamic aci;4-aminobenzoyl-gly-pro-d-leu-d-ala hydroxamic acid;P-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID
- CBNumber
- CB0456098
- Molecular Formula
- C23H34N6O6
- Formula Weight
- 490.55
- MOL File
- 124168-73-6.mol
MMP INHIBITOR I Property
- Density
- 1.288±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: 1 mg/mL
- pka
- 9.34±0.40(Predicted)
- form
- solid
- color
- white
- Water Solubility
- water: 1mg/mL
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 444250
- Product name
- MMP Inhibitor I
- Purity
- The MMP Inhibitor I controls the biological activity of MMP. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
- Packaging
- 10MG
- Price
- $214
- Updated
- 2025/07/31
- Product number
- A4336
- Product name
- 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid
- Purity
- ≥95% (HPLC)
- Packaging
- 5mg
- Price
- $278
- Updated
- 2023/06/20
- Product number
- FA111048
- Product name
- 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
- Packaging
- 25mg
- Price
- $410
- Updated
- 2021/12/16
- Product number
- FA111048
- Product name
- 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH trifluoroacetate salt
- Packaging
- 50mg
- Price
- $697
- Updated
- 2021/12/16
- Product number
- CHM0115060
- Product name
- 4-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $762.94
- Updated
- 2021/12/16
MMP INHIBITOR I Chemical Properties,Usage,Production
Uses
FN-439 is a selective collagenase-1 inhibitor. FN-439 inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 can be used for the research of cancer and inflammation[1][2].
Biological Activity
Collagenase Inhibitor
in vivo
FN-439 significantly decreases neutrophils and macrophages, shows extensive bone formation and active cementogenesis in the periapical region when has a combination with ofloxaci[2].
References
[1] U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8. DOI:10.1023/a:1006639214618
[2] H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73. DOI:10.1016/S0099-2399(96)80061-6
MMP INHIBITOR I Preparation Products And Raw materials
Raw materials
Preparation Products
MMP INHIBITOR I Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91