3,5-Dihydroxybenzyl alcohol
- Product Name
- 3,5-Dihydroxybenzyl alcohol
- CAS No.
- 29654-55-5
- Chemical Name
- 3,5-Dihydroxybenzyl alcohol
- Synonyms
- 5-(hydroxymethyl)benzene-1,3-diol;2-(hydroxymethyl)benzene-1,4-diol;3,5-Dihydroxybenzyl;RARECHEM AL BD 0252;3,5-dihydroxy Methanol;3,5-Dihydroxybenzyl alc;hydroxyMethyl)resorcinol;3-dihidroxybenzylalcohol;3，5-dihidroxybenzylalcohol;3,5-dihydroxy-benzylalcoho
- CBNumber
- CB0458906
- Molecular Formula
- C7H8O3
- Formula Weight
- 140.14
- MOL File
- 29654-55-5.mol
3,5-Dihydroxybenzyl alcohol Property
- Melting point:
- 182-186 °C (dec.) (lit.)
- Boiling point:
- 216.62°C (rough estimate)
- Density
- 1.2127 (rough estimate)
- refractive index
- 1.4638 (estimate)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Soluble in DMSO, methanol.
- form
- Crystalline Powder
- pka
- 9.23±0.10(Predicted)
- color
- Off-white to beige-pink or gray
- BRN
- 2326351
- InChI
- InChI=1S/C7H8O3/c8-4-5-1-6(9)3-7(10)2-5/h1-3,8-10H,4H2
- InChIKey
- NGYYFWGABVVEPL-UHFFFAOYSA-N
- SMILES
- C1(O)=CC(CO)=CC(O)=C1
- CAS DataBase Reference
- 29654-55-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- DO1400000
- HS Code
- 29052900
- Toxicity
- mouse,LD50,intravenous,750mg/kg (750mg/kg),British Journal of Pharmacology and Chemotherapy. Vol. 22, Pg. 221, 1964.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 396206
- Product name
- 3,5-Dihydroxybenzyl alcohol
- Purity
- 99%
- Packaging
- 5g
- Price
- $67.6
- Updated
- 2024/03/01
- Product number
- 396206
- Product name
- 3,5-Dihydroxybenzyl alcohol
- Purity
- 99%
- Packaging
- 25g
- Price
- $107.2
- Updated
- 2024/03/01
- Product number
- D2656
- Product name
- 3,5-Dihydroxybenzyl Alcohol
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $104
- Updated
- 2024/03/01
- Product number
- D2656
- Product name
- 3,5-Dihydroxybenzyl Alcohol
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $508
- Updated
- 2024/03/01
- Product number
- B25248
- Product name
- 3,5-Dihydroxybenzyl alcohol, 98%
- Packaging
- 1g
- Price
- $31.7
- Updated
- 2023/06/20
3,5-Dihydroxybenzyl alcohol Chemical Properties,Usage,Production
Description
3,5-dihydroxybenzyl alcohol: a kind of critical medicine intermediate and chemical intermediate
3,5-Dihydroxybenzyl alcohol is a colourless product with a melting point of 182~186℃. It is soluble in water, ethanol, ether, THF and other polar solvents. This compound is a vital pharmaceutical and chemical intermediate and an essential raw material for organic synthesis. It can be used as a raw material to prepare pseudo-choleretic drugs with intellectual property rights in my country, such as pseudo-amyloid, bonicon, bromoprim, and resveratrol. It has antibacterial, anti-inflammatory, anti-tumour, antioxidant, anti-shock, and coronary heart disease prevention and treatment biological activities. It is mainly isolated from Veratrum ussuri and Veratrum hairy spike produced in Northeast China; it can also be used to synthesize pharmaceutical intermediates such as 3,5-dihydroxybenzaldehyde and 3,5-dihydroxybenzoyl ethyl ketone, and can also be used as an additive in the field of fine chemicals such as daily chemicals.
Chemical Properties
White to light yellow crystal powder
Uses
3,5-Dihydroxybenzyl Alcohol is a used as a dendrimer building block.
Uses
3,5-Dihydroxybenzyl alcohol may be used as monomer for the synthesis of a series of monodisperse dendritic polyether macromolecules.?It may be employed in the synthesis of dimethylsilyl linked dihydroxybenzyl alcohol based dendrimers.
General Description
Aggregation behavior of 3,5-dihydroxybenzyl alcohol based dendritic polymers has been investigated by dynamic light scattering and transmission electron microscopy. Preparation of dendritic polyether macromolecules based on 3, 5-dihydroxybenzyl alcohol building block and having carboxylate groups as chain-ends has been described.
Synthesis
Preparation of 3,5-dihydroxybenzyl alcohol: Add 50mL THF to a 250mL three-necked flask, add 3.15g (0.082mol) NaBH, 2.38g (0.01mol) 3,5-Diacetoxybenzoic acid, control the temperature at 0 degrees in an ice-water bath, slowly drop 60ml THF solution containing 9g (0.036mol) I2, and then add 4.76g (0.02mol) of the product from the previous step after the dropwise addition, heat to reflux, and track the reaction with a plate. After the reaction is completed, concentrate to dryness under reduced pressure, add 100mL saturated NaHCO solution, extract with ether, combine the organic layers, dry with anhydrous magnesium sulfate, filter, concentrate, and recrystallize with hot water to obtain 3.5g white crystals with a yield of 83.2%.
3,5-Dihydroxybenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Dihydroxybenzyl alcohol manufacturers
- Product
- 3,5-Dihydroxybenzyl alcohol 29654-55-5
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500KGS
- Release date
- 2021-11-08
- Product
- 3,5-Dihydroxybenzyl alcohol 29654-55-5
- Price
- US $10.00-8.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-05
- Product
- 3,5-dihydroxy-benzyl alcoho 29654-55-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 3 tons
- Release date
- 2022-12-06