ChemicalBook > CAS DataBase List > Solvent Red 43

Solvent Red 43

Product Name: Solvent Red 43
CAS No.: 15086-94-9
Chemical Name: Solvent Red 43
Synonyms: EOSIN Y;EOSIN Y DISODIUM SALT;Solvent Red;EOSINE Y;RED 21;AKA223;EOSINE;BROMOFLUORESCEIN;EOSIN METHYLENE BLUE;EOSIN G
CBNumber: CB0458911
Molecular Formula: C20H8Br4O5
Formula Weight: 647.89
MOL File: 15086-94-9.mol

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Solvent Red 43 Property

Melting point:: 300 °C
Boiling point:: 640.3±55.0 °C(Predicted)
Density: 1.02 g/mL at 20 °C
refractive index: 1.5000 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: H₂O: 0.1 g/mL, dark red
form: Liquid
Colour Index: 45380:2
pka: 6.97±0.20(Predicted)
color: White to Light yellow to Red
λmax: 524 nm
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: DBZJJPROPLPMSN-UHFFFAOYSA-N
CAS DataBase Reference: 15086-94-9
IARC: 3 (Vol. 15, Sup 7) 1987
EPA Substance Registry System: Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabromo-3',6'-dihydroxy- (15086-94-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26-24/25
RIDADR: UN 1170 3/PG 2
WGK Germany: 3
RTECS: LM5850000
HS Code: 32041919

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E4009
Product name: Eosin Y
Purity: Dye content ~99%
Packaging: 5g
Price: $93.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: 230251
Product name: Eosin Y
Packaging: 25g
Price: $180
Updated: 2025/07/31

TCI Chemical

Product number: T0035
Product name: Tetrabromofluorescein
Purity: >95.0%(HPLC)(T)
Packaging: 25g
Price: $77
Updated: 2025/07/31

Sigma-Aldrich

Product number: E4009
Product name: Eosin Y
Purity: Dye content ~99%
Packaging: 25g
Price: $418.07
Updated: 2025/07/31

TRC

Product number: E561015
Product name: EosinAcidC.I.No.45380
Packaging: 5g
Price: $50
Updated: 2021/12/16

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Solvent Red 43 Chemical Properties,Usage,Production

Chemical Properties

orange-brown powder

Uses

Eosin Acid C.I. No. 45380 (CAS# 15086-94-9) is a photo-senseitive organic catalyst and has been used in the photocatalytic, diastereoselective additions of 1-sulfoximidoyl-1,2-benziodoxoles to styrenes, and in the stereoselective synthesis of 2-deoxyglycosides from glycals. Dyes and metabolites.

Definition

ChEBI: Bromoeosin is an organobromine compound. It is functionally related to a fluorescein (lactone form).

Preparation

Fluorescein (C.I. Acid Yellow 73, C.I. 45350) in water or ethanol solution bromide into four bromine derivatives, And made into a free acid form..

Biological Activity

Eosin Y is a xanthene dye and is used for the differential staining of connective tissue and cytoplasm. In histopathology, it is applied as a counterstain after hematoxylin and before methylene blue. It is also used as a background stain, thereby giving contrast to the nuclear stains.

Synthesis

2321-07-5

15086-94-9

The general procedure for the synthesis of 2',4',5',7'-tetrabromo-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthene]-3-one from 3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthene] is as follows: fluorescein in the form of the lactone (1 eq.), NaBr (16 eq.), and Oxone? ( 6 equiv, 2KHSO5-KHSO4-K2SO4) were mixed and ground in an agate mortar until uniformly fine. The resulting solid mixture was reacted in an oven at 200 °C for 12 h. Upon completion of the reaction, the target product tetrabromofluorescein (4Br-F) was obtained in near 100% yield in the commercial disodium salt form known as eosin Y. The reaction mixture was diluted with water and the product was extracted with ethyl acetate. The product was characterized by mass spectrometry (ESI-MS) and spectroscopic techniques (1H-NMR and 13C-NMR). The specific data were as follows: ESI-MS (+) of 4Br-F: m/z 670.4 [M + H]+; 1H NMR (CH3OD): δ 7.04 ppm (s, 1H and 8H), 7.23 (d, J = 8.0 Hz, 3H), 7.72 (ddd, J = 8.0, 8.0, 1.2 Hz, 5H), 7.79 (ddd, J = 8.0, 8.0, 1.2 Hz, 4H), 8.09 ppm (d, J = 8.0 Hz, 6H).

Properties and Applications

brilliant yellow red. Soluble in water and ethanol for blue light red, with yellow green fluorescence. In concentrated sulfuric acid to yellow, dilution after yellow red precipitation.

References

[1] Patent: US2008/61289, 2008, A1. Location in patent: Page/Page column 6-7
[2] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 5, p. 216
[3] Journal of the American Chemical Society, 1927, vol. 49, p. 1278
[4] Justus Liebigs Annalen der Chemie, 1876, vol. 183, p. 31
[5] Justus Liebigs Annalen der Chemie, 1910, vol. 372, p. 109

Solvent Red 43 Preparation Products And Raw materials

Raw materials

Preparation Products

MONASCUS RED

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View Lastest Price from Solvent Red 43 manufacturers

Watson Biotechnology Co.,Ltd

Product: Solvent Red 43 15086-94-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20MT
Release date: 2025-04-11

Hebei Chuanghai Biotechnology Co., Ltd

Product: Solvent Red 43 15086-94-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Shenyang Simchoice Chemical Co.,Ltd

Product: Eosin Y（Alcohol soluble） 15086-94-9
Price: US $1.00/KG
Min. Order: 25KG
Purity: 99%
Supply Ability: 500 kgs per month
Release date: 2020-08-03

15086-94-9, Solvent Red 43Related Search:

Fluorescein isothiocyanate Fluorescein Sodium EC 1.14.14.3 Phthalide Hydroxy silicone oil Furazolidone FURFURYL ALCOHOL RESIN Styrene-acrylic latex Xanthene Tetrahydrofuran Nitrofurantoin ROSE BENGAL Fluorescein EOSIN Solvent Red 1 Solvent Red 8 Solvent Red 49 Solvent Red 30

BROMO ACID J

BROMO ACID J TS, XL, OR XX

BROMOFLUORESCEIN

BRONZE BROMO ES

EOSIN Y

EOSIN Y DISODIUM SALT

EOSIN YELLOWISH WATER-SOLUBLE

EOSIN YELLOWISH Y

EOSIN Y NA-SALT

EOSIN Y, SODIUM SALT

EOSIN Y TS

EOSIN Y (YELLOWISH)

EOSINE Y

EOSIN G

EOSIN-HEMATOXYLIN

EOSIN, INSOLUBLE

EOSIN METHYLENE BLUE

EOSIN, SODIUM SALT (YELLOWISH)

TETRABROMO-FLUORESCEIN

TETRABROMOFLUORESCEIN SODIUM SALT

TETRABROMO (R) FLUORESCEIN

S NO 881

SODIUM TETRABROMOFLUORESCEIN

japanredno.223

redno.223

spiro(isobenzofuran-1(3h),9’-(9h)-xanthen)-3-one,2’,4’,5’,7’-tetrabromo-3’,6

2-(3,6-dihydroxy-2,4,5,7-tetrabromoxanthen-9-yl)-benzoic acid

RED 21

’-dihydroxy-

2’,4’,5’,7’-tetrabromo-fluorescei

9’-[9H]xanthen]-3-one,2’,4’,5’,7’-tetrabromo-3’,6’-dihydroxy-Spiro[isobenzofuran-1(3H)

bromeosin

C.I.SolventRed43

dandcredno.21

AKA223

EOSIN Y, SPIRIT SOLUBLE

EOSIN Y, SPIRIT SOLUBLE, HIGH PURITY

EOSIN Y, FREE ACID (DYE CONTENT: 99%) HIGH PURITY

EOSIN Y C.I. NO. 45380 ALCOHOL SOLUBLE BIOGICAL STAIN

Eosin Y, 1% Solution in Water

vent Red 43

D&C Red # 21 Al Lake

Field stain B

2',4',5',7'-Tetrabromo-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one

EOSIN STAIN

EOSIN DISODIUM FRP

EOSINE

EOSINE B

EOSIN 225

EOSINE J

CI NO 45380

CI NO 45380/52015

D AND C RED NO 22

HIDACID EOSINE SODA SALT

LABOTEST-BB LT00159820

HEMATOXYLIN-EOSIN ACCORDING TO EHRLICH

2'4',5',7'-TETRABROMOFLUORESCEIN

2',4',5',7'-TETRABROMOFLUORESCEIN SODIUM SALT