ChemicalBook > CAS DataBase List > (4-Fluorophenyl)acetone

(4-Fluorophenyl)acetone

Product Name
(4-Fluorophenyl)acetone
CAS No.
459-03-0
Chemical Name
(4-Fluorophenyl)acetone
Synonyms
cas 459-03-0;2-Propanone, 1-(4;4-FLUOROPHENYLACETONE;4'-FLUOROPHENYLACETONE;(P-FLUOROPHENYL)ACETONE;4-Fluorophenylacetone98%;4-Fluorophenylacetone 98%;4-Fluorophenylacetone,99%;1-(4-Fluorophenyl)acetone;4-Fluorophenylacetone pmk
CBNumber
CB0459004
Molecular Formula
C9H9FO
Formula Weight
152.17
MOL File
459-03-0.mol
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(4-Fluorophenyl)acetone Property

Boiling point:
106-107 °C/18 mmHg (lit.)
Density 
1.139 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.496(lit.)
Flash point:
197 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methyl Acetate: 50 mg/ml
form 
clear liquid
color 
Light yellow to Yellow to Orange
Specific Gravity
1.139
Water Solubility 
insoluble
BRN 
1936697
InChI
InChI=1S/C9H9FO/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5H,6H2,1H3
InChIKey
ZUEKIIWSVFBTCM-UHFFFAOYSA-N
SMILES
C(C1=CC=C(F)C=C1)C(=O)C
CAS DataBase Reference
459-03-0(CAS DataBase Reference)
NIST Chemistry Reference
(4-Fluorophenyl)acetone(459-03-0)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Flammable
HazardClass 
IRRITANT, FLAMMABLE
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
209457
Product name
(4-Fluorophenyl)acetone
Purity
98%
Packaging
10g
Price
$313
Updated
2024/03/01
TCI Chemical
Product number
F0535
Product name
4-Fluorophenylacetone
Purity
>98.0%(GC)
Packaging
5g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
F0535
Product name
4-Fluorophenylacetone
Purity
>98.0%(GC)
Packaging
25g
Price
$86
Updated
2024/03/01
Alfa Aesar
Product number
L11720
Product name
4-Fluorophenylacetone, 99%
Packaging
1g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
L11720
Product name
4-Fluorophenylacetone, 99%
Packaging
5g
Price
$91.65
Updated
2024/03/01
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(4-Fluorophenyl)acetone Chemical Properties,Usage,Production

Description

This intermediate, also known as (4-Fluorophenyl)acetone, presents as a dark yellow liquid. It is known to be insoluble in water. For best results, store in a tightly closed container in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 4-Fluorophenylacetone is incompatible with strong oxidizing agents. This chemical is a combustible liquid.

Chemical Properties

clear yellow liquid

Uses

4-Fluorophenylacetone is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It is a haloarylacetone derivative used in a study of reversed enantiopreference of an ω-transaminase by a single-point mutation.

Application

(4-Fluorophenyl)acetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors. It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor. (4-Fluorophenyl)acetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis. Brevibacterium sp. strain P7 was used as a model system and it has found that it inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.

(4-Fluorophenyl)acetone Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-Fluorophenyl)acetone Suppliers

Changzhou Share Chemical Co., Ltd
Tel
0519-82619998
Fax
+86-519-82619997
Email
wu@sharechem.com
Country
China
ProdList
29
Advantage
54
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
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View Lastest Price from (4-Fluorophenyl)acetone manufacturers

Dorne Chemical Technology co. LTD
Product
4-Fluorophenylacetone 459-03-0
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
10 ton
Release date
2024-03-26
HebeiShuoshengImportandExportco.,Ltd
Product
4-Fluorophenylacetone 459-03-0
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-07
Shandong Deshang Chemical Co., Ltd.
Product
(4-Fluorophenyl)acetone 459-03-0
Price
US $9.30-7.20/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-21

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