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(4-Fluorophenyl)acetone

Product Name
(4-Fluorophenyl)acetone
CAS No.
459-03-0
Chemical Name
(4-Fluorophenyl)acetone
Synonyms
cas 459-03-0;2-Propanone, 1-(4;4-FLUOROPHENYLACETONE;4'-FLUOROPHENYLACETONE;(P-FLUOROPHENYL)ACETONE;4-Fluorophenylacetone98%;4-Fluorophenylacetone 98%;4-Fluorophenylacetone,99%;1-(4-Fluorophenyl)acetone;4-Fluorophenylacetone pmk
CBNumber
CB0459004
Molecular Formula
C9H9FO
Formula Weight
152.17
MOL File
459-03-0.mol
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(4-Fluorophenyl)acetone Property

Boiling point:
106-107 °C/18 mmHg (lit.)
Density 
1.139 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.496(lit.)
Flash point:
197 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methyl Acetate: 50 mg/ml
form 
clear liquid
color 
Light yellow to Yellow to Orange
Specific Gravity
1.139
Water Solubility 
insoluble
BRN 
1936697
InChI
InChI=1S/C9H9FO/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5H,6H2,1H3
InChIKey
ZUEKIIWSVFBTCM-UHFFFAOYSA-N
SMILES
C(C1=CC=C(F)C=C1)C(=O)C
CAS DataBase Reference
459-03-0(CAS DataBase Reference)
NIST Chemistry Reference
(4-Fluorophenyl)acetone(459-03-0)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Flammable
HazardClass 
IRRITANT, FLAMMABLE
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
209457
Product name
(4-Fluorophenyl)acetone
Purity
98%
Packaging
10g
Price
$313
Updated
2024/03/01
TCI Chemical
Product number
F0535
Product name
4-Fluorophenylacetone
Purity
>98.0%(GC)
Packaging
5g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
F0535
Product name
4-Fluorophenylacetone
Purity
>98.0%(GC)
Packaging
25g
Price
$86
Updated
2024/03/01
Alfa Aesar
Product number
L11720
Product name
4-Fluorophenylacetone, 99%
Packaging
1g
Price
$28.65
Updated
2024/03/01
Alfa Aesar
Product number
L11720
Product name
4-Fluorophenylacetone, 99%
Packaging
5g
Price
$91.65
Updated
2024/03/01
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(4-Fluorophenyl)acetone Chemical Properties,Usage,Production

Description

This intermediate, also known as (4-Fluorophenyl)acetone, presents as a dark yellow liquid. It is known to be insoluble in water. For best results, store in a tightly closed container in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. 4-Fluorophenylacetone is incompatible with strong oxidizing agents. This chemical is a combustible liquid.

Chemical Properties

clear yellow liquid

Uses

4-Fluorophenylacetone is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields. It is a haloarylacetone derivative used in a study of reversed enantiopreference of an ω-transaminase by a single-point mutation.

Application

(4-Fluorophenyl)acetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors. It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor. (4-Fluorophenyl)acetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis. Brevibacterium sp. strain P7 was used as a model system and it has found that it inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.

(4-Fluorophenyl)acetone Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-Fluorophenyl)acetone Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
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India
ProdList
9679
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TCI Chemicals (India) Pvt. Ltd.
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--
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Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
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Alfa Aesar
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Email
tech@alfa.com
Country
India
ProdList
6905
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Reax Chemicals
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Country
India
ProdList
4217
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Oceanic Pharmachem Pvt. Ltd.
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Email
info@oceanicpharmachem.com
Country
India
ProdList
2005
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Synth Services
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Tron Quality Inventor Pvt. Ltd.
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A.J Chemicals
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Dr Prem's Molecules Pvt. Ltd.
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prem@dpmolecules.com
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CHEMSWORTH
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View Lastest Price from (4-Fluorophenyl)acetone manufacturers

Dorne Chemical Technology co. LTD
Product
4-Fluorophenylacetone 459-03-0
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
10 ton
Release date
2024-03-26
HebeiShuoshengImportandExportco.,Ltd
Product
4-Fluorophenylacetone 459-03-0
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-07
Shandong Deshang Chemical Co., Ltd.
Product
(4-Fluorophenyl)acetone 459-03-0
Price
US $9.30-7.20/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-21

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