3-METHOXYISONICOTINALDEHYDE

Product Name: 3-METHOXYISONICOTINALDEHYDE
CAS No.: 1849-52-1
Chemical Name: 3-METHOXYISONICOTINALDEHYDE
Synonyms: 3-METHOXYISONICOTINALDEHYDE;3-methoxypyridine-4-carbaldehyde;3-Methoxy-4-Pyridinecarboxaldehyde;3-Methoxypyridine-4-carboxaldehyde;4-Pyridinecarboxaldehyde, 3-methoxy-
CBNumber: CB0460150
Molecular Formula: C7H7NO2
Formula Weight: 137.14
MOL File: 1849-52-1.mol

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3-METHOXYISONICOTINALDEHYDE Property

Melting point:: 36-37 °C
Boiling point:: 80 °C(Press: 1 Torr)
Density: 1.159±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
pka: 2.86±0.10(Predicted)
Appearance: Yellow to brown Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 119591
Product name: 3-Methoxyisonicotinaldehyde
Packaging: 250.00mg
Price: $51
Updated: 2026/05/18

Matrix Scientific

Product number: 119591
Product name: 3-Methoxyisonicotinaldehyde
Packaging: 1.00g
Price: $111
Updated: 2026/05/18

Matrix Scientific

Product number: 119591
Product name: 3-Methoxyisonicotinaldehyde
Packaging: 5.00g
Price: $401
Updated: 2026/05/18

Synthonix

Product number: M32191
Product name: 3-Methoxyisonicotinaldehyde
Purity: 95+%
Packaging: 100mg
Price: $47
Updated: 2026/05/06

Synthonix

Product number: M32191
Product name: 3-Methoxyisonicotinaldehyde
Purity: 95+%
Packaging: 250mg
Price: $53
Updated: 2026/05/06

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3-METHOXYISONICOTINALDEHYDE Chemical Properties,Usage,Production

Synthesis

102074-60-2

1849-52-1

General procedure for the synthesis of 3-methoxypyridin-4-aldehyde from (3-methoxypyridin-4-yl)methanol: Manganese dioxide (843 mg) was added to a solution of ethyl acetate (10 mL) in (3-methoxypyridin-4-yl)methanol (270 mg), and the reaction was carried out at reflux for 2 hours. Subsequently, manganese dioxide (167 mg) was added to the reaction system and refluxing was continued for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and filtered to remove insoluble material. The filtrate was distilled under reduced pressure to remove the solvent, and the resulting residue was purified by silica gel column chromatography (eluent ratio: hexane/ethyl acetate = 1:1 → 0:1) to give 3-methoxypyridine-4-aldehyde (190 mg) as a white solid.

References

[1] Patent: WO2007/67511, 2007, A2. Location in patent: Page/Page column 35
[2] Patent: US2016/168139, 2016, A1. Location in patent: Paragraph 0944; 0949; 0950

3-METHOXYISONICOTINALDEHYDE Preparation Products And Raw materials

Raw materials

Sodium hydride Hexane Ammonium hydroxide Acetic anhydride N,N-Dimethylformamide Acetamide Manganese sulfate monohydrate Sodium nitrite Diethyl ether 3,4-Pyridinedicarboxylic acid Lithium Aluminum Hydride Bromine Acetic acid Sodium hydroxide Thionyl chloride Iodomethane Sulfuric acid

Preparation Products

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3-METHOXYISONICOTINALDEHYDE Suppliers

China 58 Germany 1 India 3 United States 7 Global 69

SynAsst Chemical.

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Synchem OHG

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SuZhou ShiYa Biopharmaceuticals, Inc.

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View Lastest Price from 3-METHOXYISONICOTINALDEHYDE manufacturers

Career Henan Chemical Co

Product: 3-METHOXYISONICOTINALDEHYDE 1849-52-1
Price: US $1.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-09

1849-52-1, 3-METHOXYISONICOTINALDEHYDERelated Search:

3,5-DIMETHOXYPYRIDINE-4-CARBOXALDEHYDE 3-METHOXYISONICOTINALDEHYDE 3-METHOXY-4-PYRIDINECARBOXYLIC ACID 2-BROMO-3-METHOXYPYRIDINE-4-CARBOXALDEHYDE TERT-BUTYL 4-FORMYL-5-METHOXYPYRIDIN-3-YLCARBAMATE 3-CHLORO-5-METHOXYISONICOTINALDEHYDE 3,5-Diethoxypyridine-4-carboxaldehyde 3-METHOXY-2-PHENYLQUINOLINE-4-CARBOXYLIC ACID 3-(TERT-BUTOXYCARBONYLAMINO)-5-METHOXYISONICOTINIC ACID 3-ethoxyisonicotinic acid 3-AMINO-5-METHOXYISONICOTINIC ACID 3-([(DIETHYLAMINO)CARBONYL]OXY)-4-PYRIDINECARBOXALDEHYDE 3-(4-CHLOROPHENOXY)-2-PHENYL-4-QUINOLINECARBOXYLIC ACID AURORA KA-8155 3-METHOXY-2-PHENYL-1,5-NAPHTHYRIDINE-4-CARBOXYLIC ACID 3-([(DIETHYLAMINO)CARBONYL]OXY)-4-PYRIDINECARBOXYLIC ACID 3-(2-CHLOROPHENOXY)-2-(4-CHLOROPHENYL)-4-QUINOLINECARBOXYLIC ACID 3-METHOXY-2-PHENYL-1,6-NAPHTHYRIDINE-4-CARBOXYLIC ACID

3-Methoxy-4-Pyridinecarboxaldehyde

3-methoxypyridine-4-carbaldehyde

3-METHOXYISONICOTINALDEHYDE

3-Methoxypyridine-4-carboxaldehyde

4-Pyridinecarboxaldehyde, 3-methoxy-

1849-52-1