ChemicalBook > CAS DataBase List > N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
- Product Name
- N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
- CAS No.
- 1011244-68-0
- Chemical Name
- N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide
- Synonyms
- TFAP;CS-2896;COX-1 Inhibitor IV;COX-1 Inhibitor IV(TFAP);N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide;N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide;Benzamide, N-(5-amino-2-pyridinyl)-4-(trifluoromethyl)-;Cyclooxygenase,COX,inhibit,Endogenous Metabolite,TFAP,Inhibitor
- CBNumber
- CB04663492
- Molecular Formula
- C13H10F3N3O
- Formula Weight
- 281.23
- MOL File
- 1011244-68-0.mol
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N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Property
- Boiling point:
- 360.8±42.0 °C(Predicted)
- Density
- 1.425±0.06 g/cm3(Predicted)
- storage temp.
- +2C to +8C
- solubility
- DMF: 5mg/mL; DMSO: 10mg/mL; Ethanol: 10mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2mg/mL
- form
- Off-white solid
- pka
- 11.02±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 26745
- Product name
- TFAP
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26745
- Product name
- TFAP
- Packaging
- 25mg
- Price
- $456
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26745
- Product name
- TFAP
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 26745
- Product name
- TFAP
- Packaging
- 10mg
- Price
- $199
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-0063093
- Product name
- TFAP
- Purity
- 99.97%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
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N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Chemical Properties,Usage,Production
Biological Activity
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a cell-permeable and selective cyclooxygenase-1 (COX-1) inhibitor with IC50 of 0.8 μM.
in vitro
TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC 50 of 0.8 μM, while that against COX-2 is over 200 μM.
target
| Target | Value |
| COX-1 (Cell-free assay) | 0.8 μM |
N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(5-Amino-2-pyridinyl)-4-trifluoromethylbenzamide Suppliers
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