7-CHLORO-4-QUINAZOLINOL

Product Name: 7-CHLORO-4-QUINAZOLINOL
CAS No.: 31374-18-2
Chemical Name: 7-CHLORO-4-QUINAZOLINOL
Synonyms: Compound Fr12428;7-CHLORO-4-QUINAZOLINOL;7-CHLOROQUINAZOLIN-4-OL;7-Chloroquinazolin-4-one;7-Chloro-4(3H)-quinazolone;7-Chloro-3H-quizolin-4-one;7-CHOROQUINAZOLIN-4(3H)-ONE;7-Chloroquinazolin-4(1H)-one;7-chloro-1H-quinazolin-4-one;7-Chloroquinazolin-4(3H)-one
CBNumber: CB0470643
Molecular Formula: C8H5ClN2O
Formula Weight: 180.59
MOL File: 31374-18-2.mol

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7-CHLORO-4-QUINAZOLINOL Property

Melting point:: 251-253 °C
Boiling point:: 331.7±44.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 0.36±0.20(Predicted)
Appearance: Off-white to light brown Solid
InChI: InChI=1S/C8H5ClN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12)
InChIKey: PMLONMIODRHERC-UHFFFAOYSA-N
SMILES: N1C2=C(C=CC(Cl)=C2)C(=O)NC=1

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3720
Product name: 7-Chloroquinazolin-4(1H)-one
Purity: min. 98.0 %
Packaging: 1G
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: C3720
Product name: 7-Chloroquinazolin-4(1H)-one
Purity: min. 98.0 %
Packaging: 5G
Price: $121
Updated: 2025/07/31

TRC

Product number: C381203
Product name: 7-Chloro-4-hydroxyquinazoline
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 073870
Product name: 7-Chloro-4-hydroxyquinazoline
Purity: 95+%
Packaging: 10g
Price: $69
Updated: 2021/12/16

AK Scientific

Product number: W5341
Product name: 7-Chloro-4-hydroxyquinazoline
Packaging: 1g
Price: $70
Updated: 2021/12/16

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7-CHLORO-4-QUINAZOLINOL Chemical Properties,Usage,Production

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1305, 1946 DOI: 10.1021/ja01211a058

Synthesis

3473-63-0

89-77-0

31374-18-2

The general procedure for the synthesis of 7-chloro-4(3H)-quinazolinone from formamidine acetate and 2-amino-4-chlorobenzoic acid was as follows: 10 g of 2-amino-4-chlorobenzoic acid (BB1) and 8 g of formamidine acetate (1.3 eq.) were added to a 100 ml eggplant flask and mixed thoroughly. The mixture was placed in a microwave reactor and reacted at 60% power for 4 min. After completion of the reaction, it was cooled to room temperature, 30 ml of water was added, stirred and the solid product was collected by filtration. The resulting product was 7-chloro-4(3H)-quinazolinone (BB2) in a yield of 10 g with 95% yield.

References

[1] Patent: CN103570738, 2016, B. Location in patent: Paragraph 0303; 0304; 0306
[2] Patent: CN103382182, 2016, B. Location in patent: Paragraph 0272-0275
[3] Patent: WO2012/88712, 2012, A1. Location in patent: Page/Page column 16
[4] MedChemComm, 2015, vol. 6, # 1, p. 222 - 229

7-CHLORO-4-QUINAZOLINOL Preparation Products And Raw materials

Raw materials

Preparation Products

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7-CHLORO-4-QUINAZOLINOL Suppliers

Canada 1 China 144 Germany 2 India 2 The Netherlands 1 Ukraine 1 United Kingdom 4 United States 19 Global 174

Anhui Yongsheng Pharmaceutical Technology Co., Ltd

Tel: 181-3307-5798 18017383231
Email: 983544897@qq.com
Country: China
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Yangzhou Siyu Chemical Co.,Ltd.

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Energy Chemical

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Jia Xing Isenchem Co.,Ltd

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Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
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Shanghai Paulshine Chemical Co., Ltd.

Tel: +86-021-37788663
Fax: +86-021-37788663
Country: China
ProdList: 186
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View Lastest Price from 7-CHLORO-4-QUINAZOLINOL manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 7-CHLORO-4-QUINAZOLINOL 31374-18-2
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-20

Career Henan Chemical Co

Product: 7-CHLORO-4-QUINAZOLINOL 31374-18-2
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2018-07-31

31374-18-2, 7-CHLORO-4-QUINAZOLINOLRelated Search:

7-CHLORO-3,4-DIHYDROQUINAZOLIN-4-ONE 7-CHLORO-4-QUINAZOLINOL 7-chloroquinazoline-2,4(1H,3H)-dione 5-Chloro-3H-quinazolin-4-one 6-Chloro-4-hydroxyquinazoline 7-Bromo-6-chloro-4-quinazolinone 4-Hydroxyquinazoline 6-Nitro-7-Chloro-4-HydroxyQuinazoline 6-BROMO-7-CHLOROQUINAZOLIN-4-OL 7-CHLORO-2-METHYL-1H-QUINAZOLIN-4-ONE 7-CHLORO-2-METHYL-3-(5-METHYL-2-PYRIDINYL)-4(3H)-QUINAZOLINONE 7-CHLORO-2-METHYL-3-(1H-1,2,4-TRIAZOL-3-YL)-4(3H)-QUINAZOLINONE 3-(1H-1,3-BENZIMIDAZOL-2-YL)-7-CHLORO-2-METHYL-4(3H)-QUINAZOLINONE 7-CHLORO-3-(2,4-DICHLORO-5-METHOXYPHENYL)-2-SULFANYL-4(3H)-QUINAZOLINONE 7-CHLORO-2-METHYL-3-(1,3-THIAZOL-2-YL)-4(3H)-QUINAZOLINONE 7-CHLORO-2-METHYL-3-(1,3,4-THIADIAZOL-2-YL)-4(3H)-QUINAZOLINONE 2,7-DICHLOROQUINAZOLIN-4-OL 7-CHLORO-3-(2,4-DICHLORO-5-ISOPROPOXYPHENYL)-2-(METHYLSULFANYL)-4(3H)-QUINAZOLINONE

7-CHLOROQUINAZOLIN-4-OL

7-CHLORO-4(1H)-QUINAZOLINONE

7-CHLORO-4-QUINAZOLINOL

7-CHLORO-4-HYDROXYQUINAZOLINE

7-Chloro-4(3H)-quinazolone

7-Chloroquinazolin-4(3H)-one

7-Chloroquinazolin-4-one

7-chloro-1H-quinazolin-4-one

4(3H)-Quinazolinone, 7-chloro-

7-Chloroquinazolin-4(1H)-one

7-Chloro-4(3H-quinazolin-4-one

7-Chloro-3<i>H</i>-quinazolin-4-one

7-chloro-4(3H)-quinazolinone

7-CHLORO-4-QUINAZOLINOL###31374-18-2

7-Chloro-4-Hydroxyquinazoline(WX636185)

7-Chloro-3H-quizolin-4-one

7-chloro-1,4-dihydroquinazolin-4-one

7-CHOROQUINAZOLIN-4(3H)-ONE

Cyclopropanamine,1-ethyl-,hydrochloride(1:5)

Benzenesulfonylchloride,9-ethoxy-

Compound Fr12428

31374-18-2

128517-87-2

Alcohols and Derivatives

Heterocycles