ChemicalBook > CAS DataBase List > Bufotenine

Bufotenine

Product Name
Bufotenine
CAS No.
487-93-4
Chemical Name
Bufotenine
Synonyms
Cohoba;DM5-HT;Mapine;Mappin;NSC 89;Mappine;bufotenin;BUFOTENINE;Bafotenine;Buffoonish
CBNumber
CB0471554
Molecular Formula
C12H16N2O
Formula Weight
204.27
MOL File
487-93-4.mol
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Bufotenine Property

Melting point:
62-64°C
Boiling point:
bp0.1 320°
Density 
1.0565 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
2℃
storage temp. 
Refrigerator, Under Inert Atmosphere
solubility 
Bufotenine is soluble in dilute acids and alkalis.
pka
10.11±0.40(Predicted)
EPA Substance Registry System
1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]- (487-93-4)
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Safety

Hazard Codes 
F,Xn
Risk Statements 
11-20/21/22-36
Safety Statements 
16-36/37
RIDADR 
1544
WGK Germany 
2
HazardClass 
6.1(b)
PackingGroup 
III
DEA Controlled Substances
CSCN: 7433
CSA SCH: Schedule I
NARC: No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015871
Product name
3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-OL
Purity
95.00%
Packaging
5MG
Price
$756.25
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015871
Product name
3-(2-DIMETHYLAMINO-ETHYL)-1H-INDOL-5-OL
Purity
95.00%
Packaging
50MG
Price
$1732.5
Updated
2021/12/16
Arctom
Product number
CFN91165
Product name
Bufotenine
Purity
≥98%
Packaging
10mg
Price
$318
Updated
2021/12/16
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Bufotenine Chemical Properties,Usage,Production

Chemical Properties

Bufotenine is an indole alkaloid obtained from the seeds and leaves of Piptadenia peregrine and P. macrocarpa. It has also been isolated from the skin glands of toads (Bufo species). The base is typically seen as white crystalline powder and the oxalate hydrate as a lavender to brown powder. The oxalate hydrate is slightly soluble in chloroform and can be separated from chloroform insoluble material for analysis.

History

Bufotenin was isolated from toad skin, and named by the Austrian chemist Handovsky at the University of Prague during World War I.The structure of bufotenine was confirmed in 1934 by Heinrich Wieland's laboratory in Munich, and the first reported synthesis of bufotenine was by Toshio Hoshino and Kenya Shimodaira in 1935.

Uses

Controlled substance (hallucinogen).
Bufotenine is a hallucinogenic serotonin analog found in frog and toad skins, mushrooms, plants and some mammals (especially in the brains, plasma, and urine of schizophrenics). It is a potent hallucinogen used in its natural state by several shaman sects and in some drug abuse situations in the United States and Australia. It causes schizophrenia and other psychotic symptoms.

Definition

ChEBI: Bufotenine is a tertiary amine that consists of N,N-dimethyltryptamine bearing an additional hydroxy substituent at position 5. It has a role as a hallucinogen and a coral metabolite. It is a tryptamine alkaloid and a tertiary amine. It derives from a N,N-dimethyltryptamine.

Bufotenine Preparation Products And Raw materials

Raw materials

Preparation Products

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487-93-4, BufotenineRelated Search:


  • BUFOTENINE
  • 1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]-
  • 3-(2-(dimethylamino)ethyl)-indol-5-o
  • 3-(2-dimethylaminoethyl)-5-indolol
  • 3-(beta-dimethylaminoethyl)-5-hydroxyindole
  • 3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol
  • 3-[2-(Dimethylamino)ethyl]-5-indolol
  • 3-[2-(Dimethylamino)ethyl]indol-5-ol
  • 3-[beta-(Dimethylamino)ethyl]-5-hydroxyindole
  • 5-Hydroxy-N,N-dimethyltryptamine
  • bufotenin
  • Cinobufotenine
  • Cohoba
  • Dimethylserotonin
  • DM5-HT
  • Indol-5-ol, 3-[2-(dimethylamino)ethyl]-
  • Mapine
  • Mappin
  • Mappine
  • N,N-Dimethyl-5-hydroxytryptamine
  • N,N-Dimethylserotonin
  • Bafotenine
  • 3-[2-(Dimethylamino)ethyl]-5-hydroxy-1H-indole
  • 3-(β-DiMethylaMinoethyl)-5-hydroxyindole
  • NSC 89
  • Bufotenine solution
  • Buffoonish
  • 487-93-4
  • Amines
  • Aromatics
  • Heterocycles