7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one Property

Boiling point:

58-64 °C (0.5 mmHg)

Density 

1.44±0.1 g/cm3(Predicted)

refractive index 

1.5150

Flash point:

127-128°C/25mm

storage temp. 

Refrigerator (+4°C)

form 

liquid

color 

Clear, dark orange

BRN 

2045059

CAS DataBase Reference

5307-99-3(CAS DataBase Reference)

Safety

Hazard Codes 

Xi,C

Risk Statements 

36/37/38-34-22

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3265 8 / PGIII

WGK Germany 

2

Hazard Note 

Irritant

HS Code 

2914290090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one Chemical Properties,Usage,Production

Chemical Properties

clear brown liquid

Synthesis

Under nitrogen protection, to a solution of dichloracetyl chloride (34 g, 0.23 mol) and cyclopentadiene(60 ml, 0.7 mol) in pentane (230 ml), heated to reflux in a three-necked flask with constant pressure funnel and condenser tube, was added dropwise via funnel triethylamine (24 g, 0.24 mol) in pentane (100 ml) with mechanical stirring during 4 hours, and a lot of white triethylamine hydrochloride was produced. After reflux for 2 hours, water (80 ml) was added to dissolve the triethylamine hydrochloride. The reaction mixture was extracted with pentane (2 × 60ml). The combined extracts were filtered and dried over anhydrous Na2SO4, and concentrated in vacuo to give brownish black oil. Fraction of reduced pressure distillation at 83~87 °C/400 Pa was collected to give 7,7-Dichlorobicyclo[3.2.0]hept-2-en-6-one (2, 33.5 g) as a colorless oil.