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K-604 dihydrochloride

Product Name
K-604 dihydrochloride
CAS No.
217094-32-1
Chemical Name
K-604 dihydrochloride
Synonyms
K-604 2HCl;K-604 (K604);K-604 >=98% (HPLC);K-604 dihydrochloride;2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride;K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
CBNumber
CB04797074
Molecular Formula
C23H31ClN6OS3
Formula Weight
539.17
MOL File
217094-32-1.mol
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K-604 dihydrochloride Property

storage temp. 
2-8°C
solubility 
DMSO: 62.5 mg/mL (108.57 mM)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1837
Product name
K-604
Purity
≥98% (HPLC)
Packaging
5mg
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1837
Product name
K-604
Purity
≥98% (HPLC)
Packaging
25mg
Price
$313.8
Updated
2024/03/01
ChemScene
Product number
CS-0018788
Product name
K-604dihydrochloride
Purity
>99.0%
Packaging
10mg
Price
$390
Updated
2021/12/16
ChemScene
Product number
CS-0018788
Product name
K-604dihydrochloride
Purity
>99.0%
Packaging
5mg
Price
$230
Updated
2021/12/16
DC Chemicals
Product number
DC21196
Product name
K-604
Purity
>98%
Packaging
100mg
Price
$700
Updated
2021/12/16
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K-604 dihydrochloride Chemical Properties,Usage,Production

Biological Activity

K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with IC50 of 0.45±0.06 μM.

in vivo

Using F1B hamsters, an animal model susceptible to diet-induced hyperlipidemia and atherosclerosis, the effects of K-604 dihydrochloride on aortic lesion areas and plasma cholesterol levels are assessed.

target

ACAT-1

< span> 0.45 μM (IC 50 )

ACAT-2

102.85 μM (IC 50 )

K-604 dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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K-604 dihydrochloride Suppliers

China 23 United States 4 Global 27
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58

217094-32-1, K-604 dihydrochlorideRelated Search:


  • K-604 dihydrochloride
  • K-604 (K604)
  • K-604 >=98% (HPLC)
  • K-604 2HCl
  • 2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride
  • K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
  • 217094-32-1