4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

Product Name: 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
CAS No.: 570407-42-0
Chemical Name: 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine
Synonyms: Avatrapa impurity 10;Avatrombopag Impurity 47;Avatrombopag Impurity 13;Avatroposide impurities5;Avatroposide impurities19;2-Thiazolamine, 4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-;5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine4-(4-chlorothiophen-2-yl)-;4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine;4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-y1)thiazol-2-amine;4-(4-Chloro-thiophen-2-yl)-5-(4-cyclohexyl-piperazin-1-yl)-thiazol-2-ylamine
CBNumber: CB04800390
Molecular Formula: C17H23ClN4S2
Formula Weight: 382.97
MOL File: 570407-42-0.mol

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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Property

Boiling point:: 560.0±50.0 °C(Predicted)
Density: 1.345±0.06 g/cm3(Predicted)
pka: 7.58±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Chemical Properties,Usage,Production

Uses

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine is a valuable organic compound that could be used as an intermediate to synthesize thrombopoietin

Synthesis

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine is synthesize from the reacton of 4- (4-Chloro-2-thienyl) -5-bromo-2-thiazolylamine with cyclohexylpiperazine. The reaction mixture was extracted with water and EtOAc. The combined organic phases were washed with distilled water and brine and dried to afford 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine.

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine Suppliers

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View Lastest Price from 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Avatrombopag Impurity 7 570407-42-0
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-02

Zison Pharmaceutical (Shandong) Co., Ltd.

Product: 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine 570407-42-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98% by HPLC
Supply Ability: 20kg/month
Release date: 2023-01-05

Jinan Ande Pharmaceutical Co.,Ltd.

Product: 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine 570407-42-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100
Release date: 2021-12-20

570407-42-0, 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amineRelated Search:

Unii-4U07F515lg Eltrombopag Ibopamine Hydrochloride Lusutrombopag Avatrombopag Avatrombopag maleate 4-(4-Chloro-2-thienyl)-2-thiazolamine 5-bromo-4-(4-chlorothiophen-2-yl)thiazol-2-amine 1-Cyclohexylpiperazine

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine

2-Thiazolamine, 4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-

Avatrombopag Impurity 13

5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine4-(4-chlorothiophen-2-yl)-

Avatrombopag Impurity 47

Avatroposide impurities19

4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-y1)thiazol-2-amine

4-(4-Chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine (Avatrombopag Impurity)

Avatroposide impurities5

Avatrapa impurity 10

4-(4-Chloro-thiophen-2-yl)-5-(4-cyclohexyl-piperazin-1-yl)-thiazol-2-ylamine

570407-42-0

C17H23ClN4S2

Intermediate