5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester

Product Name: 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
CAS No.: 1841134-72-2
Chemical Name: 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
Synonyms: BCN-exo-PEG3-NH2;exo BCN-PEG3-NH2;exo BCN-PEG3-amine;BCN-PEG3-AMINE (EXO);5,8,11-Trioxa-2-azatridecanoic acid, 13-amino-, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
CBNumber: CB04809469
Molecular Formula: C19H32N2O5
Formula Weight: 368.47
MOL File: 1841134-72-2.mol

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5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Property

Boiling point:: 519.6±40.0 °C(Predicted)
Density: 1.14±0.1 g/cm3(Predicted)
pka: 12.05±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Chemical Properties,Usage,Production

Biological Activity

BCN-?exo-?PEG3-?NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Suppliers

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Changzhou Hopschain Chemical Co.,Ltd.

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View Lastest Price from 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: exo BCN-PEG3-amine 1841134-72-2
Price: US $0.00/mg
Min. Order: 50mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-20

1841134-72-2, 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl esterRelated Search:

BCN-OH endo-BCN-PEG4-acid - exo BCN-O-PNB endo BCN-O-PNB endo-BCN-PEG4-NHS ester (1R,8S,9r)-bicyclo[6.1.0]nonan-9-ylmethanol

BCN-PEG3-AMINE (EXO)

exo BCN-PEG3-NH2

BCN-exo-PEG3-NH2

exo BCN-PEG3-amine

5,8,11-Trioxa-2-azatridecanoic acid, 13-amino-, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester

1841134-72-2

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