5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester

Product Name: 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
CAS No.: 1883512-27-3
Chemical Name: 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
Synonyms: BCN-endo-PEG3-NH2;endo BCN-PEG3-NH2;endo-BCN-PEG3-amine;BCN-PEG3-AMINE (ENDO);5,8,11-Trioxa-2-azatridecanoic acid, 13-amino-, (1α,8α,9β)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
CBNumber: CB74809468
Molecular Formula: C19H32N2O5
Formula Weight: 368.47
MOL File: 1883512-27-3.mol

More

Less

5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Property

Boiling point:: 519.6±40.0 °C(Predicted)
Density: 1.14±0.1 g/cm3(Predicted)
storage temp.: -20°C, sealed storage, away from moisture and light
form: Oil
pka: 12.05±0.46(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-24510
Product name: endo-BCN-PEG3-amine
Purity: 98%
Packaging: 100mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-24510
Product name: endo-BCN-PEG3-amine
Purity: 98%
Packaging: 250mg
Price: $650
Updated: 2021/12/16

More

Less

5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Chemical Properties,Usage,Production

Description

endo-BCN-PEG3-amine is a click chemistry linker containing a BCN and an amine group. The BCN group can react with azide-tagged biomolecules under mile condition. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Uses

endo-BCN-PEG3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG3-NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Suppliers

China 31 United States 2 Global 33

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10197
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

Chongqing Yusi medical technology cable Co., Ltd.

Tel: 023-62795528 18896157519
Email: 18896157519@139.com
Country: China
ProdList: 4770
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 10784
Advantage: 58

Hangzhou Taorui Biotechnology Co., Ltd

Tel: 15268198094
Email: sales@torreybio.com
Country: China
ProdList: 3943
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29718
Advantage: 58

Zhengzhou convergence chemical co., LTD

Tel: 037155153829 18003835034
Email: 3897192574@qq.com
Country: China
ProdList: 9995
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

More

Less

View Lastest Price from 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: endo BCN-PEG3-amine 1883512-27-3
Price: US $0.00/mg
Min. Order: 50mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-20

1883512-27-3, 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9β)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl esterRelated Search:

BCN-OH endo-BCN-PEG4-acid exo BCN-O-PNB endo BCN-O-PNB endo-BCN-PEG4-NHS ester - (1R,8S,9r)-bicyclo[6.1.0]nonan-9-ylmethanol

BCN-PEG3-AMINE (ENDO)

endo BCN-PEG3-NH2

BCN-endo-PEG3-NH2

endo-BCN-PEG3-amine

5,8,11-Trioxa-2-azatridecanoic acid, 13-amino-, (1α,8α,9β)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester

1883512-27-3

SiChem