ChemicalBook > CAS DataBase List > 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
- Product Name
- 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
- CAS No.
- 1841134-72-2
- Chemical Name
- 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester
- Synonyms
- BCN-exo-PEG3-NH2;exo BCN-PEG3-NH2;exo BCN-PEG3-amine;BCN-PEG3-AMINE (EXO);5,8,11-Trioxa-2-azatridecanoic acid, 13-amino-, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
- CBNumber
- CB04809469
- Molecular Formula
- C19H32N2O5
- Formula Weight
- 368.47
- MOL File
- 1841134-72-2.mol
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5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Property
- Boiling point:
- 519.6±40.0 °C(Predicted)
- Density
- 1.14±0.1 g/cm3(Predicted)
- pka
- 12.05±0.46(Predicted)
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5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Chemical Properties,Usage,Production
Biological Activity
BCN-?exo-?PEG3-?NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester Suppliers
- Tel
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 24072
- Advantage
- 58
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- +1-781-999-5354 +1-00000000000
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- United States
- ProdList
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View Lastest Price from 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- exo BCN-PEG3-amine 1841134-72-2
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >95.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-20
1841134-72-2, 5,?8,?11-?Trioxa-?2-?azatridecanoic acid, 13-?amino-?, (1α,?8α,?9α)?-?bicyclo[6.1.0]?non-?4-?yn-?9-?ylmethyl esterRelated Search:
BCN-OH
endo-BCN-PEG4-acid
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exo BCN-O-PNB
endo BCN-O-PNB
endo-BCN-PEG4-NHS ester
(1R,8S,9r)-bicyclo[6.1.0]nonan-9-ylmethanol