(2-pyridyldithio)-PEG4-alcohol
- Product Name
- (2-pyridyldithio)-PEG4-alcohol
- CAS No.
- 851961-99-4
- Chemical Name
- (2-pyridyldithio)-PEG4-alcohol
- Synonyms
- (2-pyridyldithio)-PEG4-alcohol;Ethanol, 2-[2-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]ethoxy]-;2-(2-(2-(2-(pyridin-2-yldisulfaneyl)ethoxy)ethoxy)ethoxy)ethan-1-ol
- CBNumber
- CB04849380
- Molecular Formula
- C13H21NO4S2
- Formula Weight
- 319.44
- MOL File
- 851961-99-4.mol
(2-pyridyldithio)-PEG4-alcohol Property
- storage temp.
- 2-8°C, stored under nitrogen
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23837
- Product name
- (2-pyridyldithio)-PEG4-alcohol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
(2-pyridyldithio)-PEG4-alcohol Chemical Properties,Usage,Production
Description
(2-pyridyldithio)-PEG2-alcohol is a PEG linker which contains a pyridyl disulfide moiety and an alcohol group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH level. The hydroxyl group allows for further derivatization of the compound. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(2-pyridyldithio)-PEG4-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
(2-pyridyldithio)-PEG4-alcohol Suppliers
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View Lastest Price from (2-pyridyldithio)-PEG4-alcohol manufacturers
- Product
- (2-pyridyldithio)-PEG4-alcohol 851961-99-4
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >99.00%
- Supply Ability
- 50mg
- Release date
- 2024-03-21