ChemicalBook > CAS DataBase List > (2-pyridyldithio)-PEG2-t-butyl ester
(2-pyridyldithio)-PEG2-t-butyl ester
- Product Name
- (2-pyridyldithio)-PEG2-t-butyl ester
- CAS No.
- 2144777-73-9
- Chemical Name
- (2-pyridyldithio)-PEG2-t-butyl ester
- Synonyms
- (2-Pyridyldithio)-PEG2-Boc;(2-pyridyldithio)-PEG2-t-butyl ester;Propanoic acid, 3-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB24849379
- Molecular Formula
- C16H25NO4S2
- Formula Weight
- 359.5
- MOL File
- 2144777-73-9.mol
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(2-pyridyldithio)-PEG2-t-butyl ester Property
- Boiling point:
- 462.8±45.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C, stored under nitrogen
- form
- Liquid
- pka
- 1.81±0.19(Predicted)
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23840
- Product name
- (2-pyridyldithio)-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $320
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23840
- Product name
- (2-pyridyldithio)-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $540
- Updated
- 2021/12/16
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(2-pyridyldithio)-PEG2-t-butyl ester Chemical Properties,Usage,Production
Description
(2-pyridyldithio)-PEG2-t-butyl ester is a PEG linker which contains a pyridyl disulfide moiety and a t-butyl ester group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH level. The t-butyl ester group can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
(2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(2-pyridyldithio)-PEG2-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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(2-pyridyldithio)-PEG2-t-butyl ester Suppliers
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View Lastest Price from (2-pyridyldithio)-PEG2-t-butyl ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- (2-pyridyldithio)-PEG2-t-butyl ester 2144777-73-9
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >95.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-21
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