(2-pyridyldithio)-PEG2-t-butyl ester
- Product Name
- (2-pyridyldithio)-PEG2-t-butyl ester
- CAS No.
- 2144777-73-9
- Chemical Name
- (2-pyridyldithio)-PEG2-t-butyl ester
- Synonyms
- (2-Pyridyldithio)-PEG2-Boc;(2-pyridyldithio)-PEG2-t-butyl ester;Propanoic acid, 3-[2-[2-(2-pyridinyldithio)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB24849379
- Molecular Formula
- C16H25NO4S2
- Formula Weight
- 359.5
- MOL File
- 2144777-73-9.mol
(2-pyridyldithio)-PEG2-t-butyl ester Property
- Boiling point:
- 462.8±45.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C, stored under nitrogen
- form
- Liquid
- pka
- 1.81±0.19(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23840
- Product name
- (2-pyridyldithio)-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23840
- Product name
- (2-pyridyldithio)-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $540
- Updated
- 2021/12/16
(2-pyridyldithio)-PEG2-t-butyl ester Chemical Properties,Usage,Production
Description
(2-pyridyldithio)-PEG2-t-butyl ester is a PEG linker which contains a pyridyl disulfide moiety and a t-butyl ester group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH level. The t-butyl ester group can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
(2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
(2-pyridyldithio)-PEG2-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
(2-pyridyldithio)-PEG2-t-butyl ester Suppliers
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32467
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 54995
- Advantage
- 58
- Tel
- 15268198094
- sales@torreybio.com
- Country
- China
- ProdList
- 3946
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 13116033142 13116033142
- kaimuchem@163.com
- Country
- China
- ProdList
- 862
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 5061
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24960
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50464
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11972
- Advantage
- 58
View Lastest Price from (2-pyridyldithio)-PEG2-t-butyl ester manufacturers
- Product
- (2-pyridyldithio)-PEG2-t-butyl ester 2144777-73-9
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >95.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-21