Clobetasone butyrate

Product Name: Clobetasone butyrate
CAS No.: 25122-57-0
Chemical Name: Clobetasone butyrate
Synonyms: eumovate;Clobetasone-17-butyrate;sn203;Emovate;molivate;CCl 5537;GR 2/1214;Kindavate;(16-beta)-);17-Butyrate
CBNumber: CB0497976
Molecular Formula: C26H32ClFO5
Formula Weight: 478.98
MOL File: 25122-57-0.mol

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Clobetasone butyrate Property

Melting point:: 90-100°
Boiling point:: 573.3±50.0 °C(Predicted)
Density: 1.1736 (estimate)
storage temp.: Refrigerator, Under Inert Atmosphere
solubility: Practically insoluble in water, freely soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent).
form: Solid
color: White to Off-White
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: FBRAWBYQGRLCEK-JGSYYNBSNA-N
SMILES: [C@]1(C(=O)CCl)(OC(=O)CCC)[C@@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C |&1:0,11,14,16,26,28,33,r|
CAS DataBase Reference: 25122-57-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 40
Safety Statements: 22-36
WGK Germany: 3
RTECS: TU4154083
HS Code: 29372290
Toxicity: mouse,LD50,intraperitoneal,500mg/kg (500mg/kg),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 14, Pg. 838, 1983.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H351Suspected of causing cancer
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C5548
Product name: Clobetasone butyrate
Purity: ≥98%
Packaging: 100mg
Price: $61.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: C2285000
Product name: Clobetasone butyrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: c2285000
Price: $153
Updated: 2024/03/01

TCI Chemical

Product number: C3510
Product name: Clobetasone Butyrate
Purity: >98.0%(HPLC)
Packaging: 50mg
Price: $30
Updated: 2024/03/01

TCI Chemical

Product number: C3510
Product name: Clobetasone Butyrate
Purity: >98.0%(HPLC)
Packaging: 250mg
Price: $194
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001137
Product name: Clobetasone butyrate for system suitability
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001137
Price: $150
Updated: 2024/03/01

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Clobetasone butyrate Chemical Properties,Usage,Production

Chemical Properties

White or almost white powder.

Uses

Clobetasone butyrate is a synthetic glucocorticoid which is used as an anti-inflammatory in the treatment of various skin disorders. As a steroid medicine, it can used on the skin to treat swelling, itching and irritation. Such as eczema, including ;contact dermatitis; psoriasis; insect bites and stings; nappy rash.

Definition

ChEBI: Clobetasone butyrate is an organic molecular entity.

Mechanism of action

Topical corticosteroids (Clobetasone butyrate) inhibit the migration of macrophages and leukocytes into areas of inflamed skin by reversing vascular dilation and permeability, resulting in decreased erythema, edema and pruritus.

Side effects

Some people get a burning or stinging feeling for a few minutes when they put clobetasone cream or ointment on their skin. Clobetasone cream contains cetostearyl alcohol and chlorocresol, which may cause local skin reactions or allergic reactions.

Clobetasone butyrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Clobetasone butyrate Suppliers

Americas 1 Canada 1 China 130 Europe 3 Germany 1 India 19 Japan 1 Switzerland 1 United Kingdom 2 United States 18 Global 177

TCI Chemicals (India) Pvt. Ltd.

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Triveni chemicals

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Pharmaffiliates Analytics and Synthetics P. Ltd

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SynZeal Research Pvt Ltd

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SYMBIOTEC PHARMALAB PRIVATE LIMITED

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AVIK PHARMACEUTICAL LIMITED

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Medilink Pharmachem

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View Lastest Price from Clobetasone butyrate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Clobetasone butyrate 25122-57-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-31

Henan Bao Enluo International TradeCo.，LTD

Product: Clobetasone butyrate 25122-57-0
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000tons
Release date: 2023-07-19

Hebei Mojin Biotechnology Co., Ltd

Product: Clobetasone butyrate 25122-57-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-06

25122-57-0, Clobetasone butyrateRelated Search:

Tributyrin Hexyl butyrate Butyric Acid Clobetasol Sodium Butyrate Isoamyl butyrate Epichlorohydrin Chloromethyl butyrate Clobetasol propionate CHLOROPHOSPHONAZO III Ethanone, 2-chloro-1-cyclopentyl- (9CI) 2-FLUOROCYCLOHEXANONE 1-Chlorohexadecane METHOXYMELONAL FEMA 3332 Clobetasone Chloroacetic acid 1-ACETOXY-3-CHLOROACETONE

)-pregn-5-en-20-one

3,17-Dihydroxy-16-methyl-(3&beta

)-3,17-Dihydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methyl|piperidinium Bromide

)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione

)-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide-d3

-Hydroxytestosterone

)-11-Hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-pregna-1,4-diene-3,20-dione

)-17-Acetyloxy-3-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide

)-16-Methyl-17,21-bis(1-oxopropoxy)pregna-1,4,9(11)-triene-3,20-dione

20R)-9-Fluoro-11,20-dihydroxy-16-methyl-3-oxopregna-1,4-dien-21-oic Acid|(Betamethasone Impurity)

)-3-(Acetyloxy)-17-hydroxy-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide

-Hydroxy Stanozolol

(16-beta)-)

11,20-trione,21-chloro-9-fluoro-17-hydroxy-16-beta-methyl-pregna-4-diene-3

21-chloro-9-fluoro-17-hydroxy-16-beta-methylpregna-1,4-diene,3,11,20-trione

eumovate

molivate

pregna-1,4-diene-3,11,20-trione,21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy

sn203

21-chloro-9-fluoro-17-hydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 17-butyrate

ClobetasolPropionate-Bp/Ep/Usp

Butyric acid, ester with 21-chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione (8CI)

CCl 5537

Emovate

GR 2/1214

Kindavate

Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-16-methyl-17-(1-oxobutoxy)-, (16β)-

Pregna-1,4-diene-3,11,20-trione, 21-chloro-9-fluoro-17-hydroxy-16β-methyl-, butyrate (8CI)

21-Chloro-9-fluoro-17-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione 17-butyrate

Clobetasone butyrate

Clobetasone-17-butyrate

H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione|(Deflazacort Impurity)

)-9-Fluoro-11,17,21-trihydroxy-16-methylpregn-4-ene-3,20-dione

)-17,21-Bis(acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione

-Hydroxy-17-epi-norethisterone

H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione

-Hydroxymestanolone

)-6-Bromo-9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxopentyl)oxy]-pregna-1,4-diene-3,20-dione

CLOBETASOLE BUTYRATE

21-Chloro-9-fluoro-16β-methyl-17-(1-oxobutoxy)pregna-1,4-diene-3,11,20-trione

21-Chloro-9-fluoro-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione=butyrate

[(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate

[(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroethanoyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate

butyric acid [(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-3,11-diketo-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] ester

17-Butyrate

Clonazepam impurity B CRS

Clobetasone butyrate for system suitability CRS

Clobetasone butyrate CRS

Clobetasone butyrate solution in Acetonitrile，100μg/mL

Clobetasone ButyrateQ: What is Clobetasone Butyrate Q: What is the CAS Number of Clobetasone Butyrate Q: What is the storage condition of Clobetasone Butyrate

4-(methylamino)-3-nitro-

21-chloro-9-fluoro-16β-methyl-3,11,20-trioxopregna-1,4-dien-17-ylbutanoate

Betamethasone Butyrate/Clobetamethasone Butyrate

Simvastatin Impurity 44

25122-57-0

C26H32ClFO5

Intermediates & Fine Chemicals

Pharmaceuticals