2-Bromo-5-chlorobenzaldehyde
- Product Name
- 2-Bromo-5-chlorobenzaldehyde
- CAS No.
- 174265-12-4
- Chemical Name
- 2-Bromo-5-chlorobenzaldehyde
- Synonyms
- 2-Bromo-5 chloraldehyde;2-Bromo-5-chlorobenzalde;2-Bromo-5-chlorobenzaldehyde;5-Chloro-2-bromobenzaldehyde;Benzaldehyde,2-bromo-5-chloro-;2-Bromo-5-chlorobenzaldehyde >
- CBNumber
- CB0500924
- Molecular Formula
- C7H4BrClO
- Formula Weight
- 219.46
- MOL File
- 174265-12-4.mol
2-Bromo-5-chlorobenzaldehyde Property
- Melting point:
- 66 °C
- Boiling point:
- 258 °C
- Density
- 1.698
- Flash point:
- 110 °C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- Crystalline
- color
- Pale yellow
- InChI
- InChI=1S/C7H4BrClO/c8-7-2-1-6(9)3-5(7)4-10/h1-4H
- InChIKey
- IIISHLMCTDMUHH-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC(Cl)=CC=C1Br
- CAS DataBase Reference
- 174265-12-4
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B2955
- Product name
- 2-Bromo-5-chlorobenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $28
- Updated
- 2025/07/31
- Product number
- B2955
- Product name
- 2-Bromo-5-chlorobenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $111
- Updated
- 2025/07/31
- Product number
- B699438
- Product name
- 2-Bromo-5-chlorobenzaldehyde
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB33572
- Product name
- 2-Bromo-5-chlorobenzaldehyde
- Packaging
- 10g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FB33572
- Product name
- 2-Bromo-5-chlorobenzaldehyde
- Packaging
- 25g
- Price
- $80
- Updated
- 2021/12/16
2-Bromo-5-chlorobenzaldehyde Chemical Properties,Usage,Production
Uses
2-Bromo-5-chlorobenzaldehyde is an important class of pharmaceutical intermediates which can be used in the synthesis of a variety of drugs. 2-Bromo-5-chlorobenzaldehyde can be used in the preparation of the compound 3-chloro-14-cyclohexyl-6-[2-(dimethylamino)ethyl]-7-oxo-5,6,7,8-tetrahydroindolo[2,1-a][2,5]benzo[di-acridine]-11-carboxylic acid, which can be used in the treatment or prevention of viral infections.
Synthesis
66192-24-3
174265-12-4
Step 2: Synthesis of 2-bromo-5-chlorobenzaldehyde; Preparation was carried out with reference to the literature method (J. Am. Chem. Soc. 2002, 124(7), 1354): a mixture of activated powdered 4A molecular sieves (800 mg/mmol of substrate), N-methylmorpholine-N-oxide (2 eq.) and 2-bromomethyl-5-chlorobenzaldehyde (1 eq.) was stirred for 2 hours at 0°C in a N -methylpyrrolidone (0.16 M) were stirred for 2 hours. Upon completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad and the filtrate was subsequently concentrated under vacuum to afford the target product 2-bromo-5-chlorobenzaldehyde in 92% yield.
References
[1] Patent: WO2006/46030, 2006, A2. Location in patent: Page/Page column 28
[2] Journal of the American Chemical Society, 2002, vol. 124, # 7, p. 1354 - 1363
2-Bromo-5-chlorobenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-5-chlorobenzaldehyde manufacturers
- Product
- 2-Bromo-5-chlorobenzaldehyde 174265-12-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-28
- Product
- 2-Bromo-5-chlorobenzaldehyde 174265-12-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 2-Bromo-5-chlorobenzaldehyde 174265-12-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.1%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14