Astragaloside A

Product Name: Astragaloside A
CAS No.: 83207-58-3
Chemical Name: Astragaloside A
Synonyms: Astragaloside IV;Astramembrannin i;Astragalin A;astragaloside A;Astragaloside A 5%;ASTRAGALOSIDE IV(P);Astragaloside IV(A);Astragaloside IV CRS;Astragaloside IV ,98%;Astragalus methylside
CBNumber: CB0500944
Molecular Formula: C41H68O14
Formula Weight: 784.97
MOL File: 83207-58-3.mol

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Astragaloside A Property

Boiling point:: 895.7±65.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMF: 20 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form: A crystalline solid
pka: 12.91±0.70(Predicted)
InChI: InChI=1/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24?,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/s3
InChIKey: QMNWISYXSJWHRY-APZLXCBQNA-N
SMILES: [C@@]123CC[C@]4(C)[C@]([H])([C@@H](O)C[C@@]4(C)[C@]1([H])C[C@H](O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O)[C@@]1([H])C(C)(C)C(O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)CC[C@]21C3)[C@@]1(C)CC[C@@H](C(O)(C)C)O1 |&1:0,3,5,7,10,12,15,17,18,20,21,23,28,35,38,40,42,46,48,52,r|
LogP: 0.628 (est)
CAS DataBase Reference: 83207-58-3

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Safety

HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16677
Product name: Astragaloside A
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 16677
Product name: Astragaloside A
Purity: ≥98%
Packaging: 5mg
Price: $233
Updated: 2024/03/01

Cayman Chemical

Product number: 16677
Product name: Astragaloside A
Purity: ≥98%
Packaging: 10mg
Price: $412
Updated: 2024/03/01

Cayman Chemical

Product number: 16677
Product name: Astragaloside A
Purity: ≥98%
Packaging: 50mg
Price: $1092
Updated: 2024/03/01

TRC

Product number: A790125
Product name: AstragalosideA
Packaging: 1mg
Price: $45
Updated: 2021/12/16

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Astragaloside A Chemical Properties,Usage,Production

Uses

Astragalosides are bioactive saponins isolated from dried roots of plants of the genus Astragalus, which is used in traditional Chinese medicine. Astragaloside A, also known as astragaloside IV, is known to have diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. More specifically, it protects cardiomyocytes from apoptosis resulting from ischemia/reperfusion and inhibits inflammation signaled through TNF-α. Furthermore, astragaloside A stimulates angiogenesis, promotes the differentiation of neural stem cells, and increases neuroregeneration.

Definition

ChEBI: A pentacyclic triterpenoid that is cycloastragenol having beta-D-xylopyranosyl and beta-D-glucopyranosyl residues attached at positions O-3 and O-6 respectively. It is isolated from <ital Astragalus membranaceus var mongholicus.

benefits

Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. It is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases. Astragaloside IV improves post-ischemic heart function and ameliorated reperfusion arrhythmias accompanied by a significant increase in myocardial antioxidative enzyme superoxide dismutase activity in rat hearts in vitro. While, Astragaloside IV's protective effect on heart function can be partially abrogated by the nitric oxide synthase inhibitor, Nomega-nitro-L-arginine methyl ester.

Health effects

As the main active ingredient of the Chinese medicine Astragalus membranaceus, Astragaloside A has a good regulatory effect on the heart. It can protect against ischemic and hypoxic cardiomyocytes, protect the heart structure, and enhance heart function.

Pharmaceutical Applications

Astrageloside A has multiple pharmacologic effects, including anti-inflammatory, antifibrotic, antioxidative stress, anti-asthma, antidiabetes, immunoregulation, and cardioprotective effect via numerous signaling pathways. According to the existing studies and clinical practices, Astragaloside A possesses potential for broad application in many diseases.

Astragaloside A Preparation Products And Raw materials

Raw materials

Preparation Products

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Astragaloside A Suppliers

China 162 India 2 United States 12 Global 176

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

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J & K SCIENTIFIC LTD.

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China Langchem Inc.

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NCE Biomedical Co.,Ltd.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Haoyuan Chemexpress Co., Ltd.

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View Lastest Price from Astragaloside A manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Astragaloside A 83207-58-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-22

Henan Fengda Chemical Co., Ltd

Product: Astragaloside A 83207-58-3
Price: US $8.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

Hebei Kingfiner Technology Development Co.Ltd

Product: Astragaloside A 83207-58-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 50000kg
Release date: 2023-09-19

83207-58-3, Astragaloside ARelated Search:

1,1,2,2-TETRAMETHYLCYCLOPROPANE Astragaloside VI AstragalosideⅠ Astragaloside IV,Astragaloside IV,ASTRAGALOSIDE CYCLOPENTADECANE 4-tert-Butylcyclohexanol Menthoxypropanediol CYCLOPENTADECANOL Astragalin Astragaloside II,Astragaloside B,Astragaloside-Ⅱ,ASTRAGALOSIDE II Astragaloside III,Astragaloside-Ⅲ ASTRAGALOSIDE I 2-METHYLPENTACOSANE 1,1-DIETHYLCYCLOPROPANE 2-(TRANS-4'-N-BUTYL-CYCLOHEXYL)PROPANE-1,3-DIOL 2-(TRANS-4-PENTYLCYCLOHEXYL)PROPANE-1,3-DIOL ASTRAGALOSIDE Astragaloside VII ASTRAGALOSIDE I(RG),Astragaloside Ⅳ

ASTRAGALOSIDE IV(P)

astragaloside A

Astragaloside IV

Astragaloside IV ,98%

Astragaloside IV(A)

Astragaloside A(Astragaloside IV)

Astramembrannin i

beta-D-Glucopyranoside, (3beta,6alpha,16beta,24R)-20,24-epoxy-16,25-dihydroxy-3-(beta-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl

β-D-Glucopyranoside, (3β,6α,16β,24R)-20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl

Astragalus Extract Astragaloside IV

Astragaloside IV-Astragaloside A

Astragaloside IV CRS

Astragalin A

Astragaloside A USP/EP/BP

Astragaloside A 5%

b-D-Glucopyranoside, (3b,6a,16b,24R)-20,24-epoxy-16,25-dihydroxy-3-(b-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl

Astragaloside A (Astramembrannin I

astragalus polysaccharide concentrated extract

Astragalus methylside

(2R,3R,4S,5S,6R)-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4-Hydroxy-3-((2S,5R)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyl-9-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)hexadecahydrocyclopenta[a]cyclopropa[e]phenanthren-7-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

83207-58-3

Inhibitors

API

Plant extracts