LEOIDIN(SH)

Product Name: LEOIDIN(SH)
CAS No.: 105350-54-7
Chemical Name: LEOIDIN(SH)
Synonyms: LEOIDIN(AS);LEOIDIN(SH);11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,4-dichloro-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-, methyl ester
CBNumber: CB0506986
Molecular Formula: C18H14Cl2O7
Formula Weight: 413.208
MOL File: 105350-54-7.mol

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LEOIDIN(SH) Property

Melting point:: 232～233℃
storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form: A solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29939
Product name: Leoidin
Packaging: 1mg
Price: $158
Updated: 2024/03/01

Cayman Chemical

Product number: 29939
Product name: Leoidin
Packaging: 5mg
Price: $589
Updated: 2024/03/01

AK Scientific

Product number: 5221CK
Product name: Leoidin
Packaging: 5mg
Price: $753
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0166359
Product name: LEOIDIN
Purity: 98.00%
Packaging: 25MG
Price: $1328.25
Updated: 2021/12/16

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LEOIDIN(SH) Chemical Properties,Usage,Production

Uses

Leoidin is an OATP1B1 and OATP1B3 inhibitor with Ki values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC50= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides[1][2].

Definition

ChEBI: 8,10-dichloro-3,9-dihydroxy-1,4,7-trimethyl-6-oxo-2-benzo[b][1,4]benzodioxepincarboxylic acid methyl ester is a carbonyl compound.

References

[1] De Bruyn T, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83(6):1257-67. DOI:10.1124/mol.112.084152
[2] Hu Y, et al. Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2016 Jul 22;60(8):4820-9. DOI:10.1128/AAC.00800-16

LEOIDIN(SH) Preparation Products And Raw materials

Raw materials

Preparation Products

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LEOIDIN(SH) Suppliers

China 13 United States 4 Global 17

Shanghai Tauto Biotech Co., Ltd.

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TargetMol Chemicals Inc.

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105350-54-7, LEOIDIN(SH)Related Search:

2-(3,5-DIMETHYLPHENOXY)BENZENECARBALDEHYDE 2,5-DIMETHYL-P-ANISALDEHYDE 3,5-Dichlorosalicylic acid 4-(2,4-DICHLOROPHENOXY)PHENOL 4-(4-Chlorophenoxy)phenol 3,5-Dichloro-4-hydroxybenzoic acid LECANORIC ACID METHYL 3,5-DICHLORO-4-HYDROXYBENZOATE 2-CHLORO-4,5-DIMETHYLPHENOL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID 5-CHLORO-2-METHYL-BENZOIC ACID METHYL ESTER METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE 3-(4-CHLOROPHENOXY)BENZALDEHYDE 2,3',5'-TRIMETHYLDIPHENYL ETHER 3,4-DIMETHOXY-2-METHYLBENZOIC ACID METHYL 6-HYDROXYVERATRATE 2,4-DIHYDROXY-5-CHLOROBENZOIC ACID 4-BENZYLOXY-2-METHYLBENZOIC ACID

LEOIDIN(SH)

LEOIDIN(AS)

11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2,4-dichloro-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-, methyl ester

105350-54-7

C18H14Cl2O7