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Domperidone Impurity 15

Product Name
Domperidone Impurity 15
CAS No.
142799-22-2
Chemical Name
Domperidone Impurity 15
Synonyms
Domperidone Impurity 15;1,3-Bis(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-bis(3-chloropropyl)-1,3-dihydro-;1,3-Bis(3-Chloropropyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
CBNumber
CB05824955
Molecular Formula
C13H16Cl2N2O
Formula Weight
287.18
MOL File
142799-22-2.mol
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Domperidone Impurity 15 Property

Melting point:
66°C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Water (Slightly, Heated, Sonicated)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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Domperidone Impurity 15 Chemical Properties,Usage,Production

Uses

1,3-Bis(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one (~90%) is an intermediate in the synthesis of 3’-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine (Domperidine Impurity F) (C365315), an impurity of the gastrokinetic and antinauseant drug Domperidone (D531100(P)), which is a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.

Domperidone Impurity 15 Preparation Products And Raw materials

Raw materials

Preparation Products

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Domperidone Impurity 15 Suppliers

Pharmaffiliates Analytics and Synthetics P. Ltd
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mktg@pharmaffiliates.com
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India
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6739
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