TERT-BUTYLCARBAMIDINE HYDROCHLORIDE
- Product Name
- TERT-BUTYLCARBAMIDINE HYDROCHLORIDE
- CAS No.
- 18202-73-8
- Chemical Name
- TERT-BUTYLCARBAMIDINE HYDROCHLORIDE
- Synonyms
- tert-ButylcarbamidineHCl;pivalamidine hydrochloride;PivalamidineHydrochloride>2,2-DIMETHYLPROPIONAMIDINE HCL;2,2-Dimethylpropanimidamide HCl;T-BUTYLCARBAMIDINE HYDROCHLORIDE;trimethylacetamidine hydrochloride;TERT-BUTYLCARBAMIDINE HYDROCHLORIDE;2-Methylisobutanamidine hydrochloride;2,2-Dimethylpropanamidine hydrochloride
- CBNumber
- CB0666352
- Molecular Formula
- C5H13ClN2
- Formula Weight
- 136.62
- MOL File
- 18202-73-8.mol
TERT-BUTYLCARBAMIDINE HYDROCHLORIDE Property
- Melting point:
- 190 °C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- powder to crystal
- color
- White to Almost white
- Sensitive
- Hygroscopic
- BRN
- 3618865
- InChIKey
- ARDGQYVTLGUJII-UHFFFAOYSA-N
- CAS DataBase Reference
- 18202-73-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- S168351
- Product name
- 2,2-DIMETHYL-PROPIONAMIDINE, HYDROCHLORIDE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- S168351
- Product name
- 2,2-DIMETHYL-PROPIONAMIDINE, HYDROCHLORIDE
- Purity
- AldrichCPR
- Packaging
- 25MG
- Price
- $29.8
- Updated
- 2024/03/01
- Product number
- P1761
- Product name
- Pivalamidine Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 5g
- Price
- $77
- Updated
- 2025/07/31
- Product number
- P1761
- Product name
- Pivalamidine Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 25g
- Price
- $233
- Updated
- 2025/07/31
- Product number
- P550695
- Product name
- PivalimidamideHydrochloride
- Packaging
- 5g
- Price
- $135
- Updated
- 2021/12/16
TERT-BUTYLCARBAMIDINE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Pivalimidamide Hydrochloride is used as a reagent in the preparation of 2-alkyl-4-aryltetrahydropyridopyrimidines and 2-alkyl-4-aryl-tetrahydropyrimidoazepines as selective 5-HT2A antagonists.
Synthesis
630-18-2
75-36-5
18202-73-8
Step (1) Preparation of tert-butylamidine hydrochloride: To a magnetically stirred mixed solution of 2,2-dimethyl-1-propanenitrile (25.0 g, 0.30 mol) and anhydrous methanol (26.8 mL, 0.79 mol) was added dropwise acetyl chloride (25 mL, 0.36 mol) and ether (30 mL) at 0 °C. After the dropwise addition, stirring was continued at 0 °C for 15 min. Subsequently, the reaction mixture was stirred at room temperature for 3 days. After completion of the reaction, white crystals were obtained by filtration, washed with ether and dried under vacuum. The dried crystals were mixed with an ethanol solution of 10% ammonia (150 mL, 0.90 mol) and stirred at room temperature for 3 days. The reaction mixture was filtered and the filtrate was concentrated to give a white solid. Recrystallization by ethanol gave a white crystalline product (18.9 g, 46% yield) with a melting point of 205°C (literature value 188°-190°C). NMR hydrogen spectrum (DMSO-d6): δ 1.22 (s, 9H), 8.63 (br d, 3H).
References
[1] Patent: US4786640, 1988, A
TERT-BUTYLCARBAMIDINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TERT-BUTYLCARBAMIDINE HYDROCHLORIDE manufacturers
- Product
- TERT-BUTYLCARBAMIDINE HYDROCHLORIDE 18202-73-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- TERT-BUTYLCARBAMIDINE HYDROCHLORIDE 18202-73-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-25