3-CHLORO-6-NITRO (1H)INDAZOLE
- Product Name
- 3-CHLORO-6-NITRO (1H)INDAZOLE
- CAS No.
- 50593-68-5
- Chemical Name
- 3-CHLORO-6-NITRO (1H)INDAZOLE
- Synonyms
- NSC84179;3-CHLORO-6-NITROINDAZOLE;3-chloro-6-nitro-1h-indazol;3-CHLORO-6-NITRO (1H)INDAZOLE;1H-Indazole, 3-chloro-6-nitro-;3-Chloro-6-nitro-1H-indazole ,97%
- CBNumber
- CB0673031
- Molecular Formula
- C7H4ClN3O2
- Formula Weight
- 197.58
- MOL File
- 50593-68-5.mol
3-CHLORO-6-NITRO (1H)INDAZOLE Property
- Melting point:
- 203-205
- Boiling point:
- 415.2±25.0 °C(Predicted)
- Density
- 1.661±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 9.01±0.40(Predicted)
- form
- solid
- color
- Yellow
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C368113
- Product name
- 3-Chloro-6-nitro-1H-indazole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR14098
- Product name
- 3-Chloro-6-nitro-1H-indazole
- Packaging
- 250mg
- Price
- $19
- Updated
- 2021/12/16
- Product number
- 4H55-5-Y5
- Product name
- 3-Chloro-6-nitro-1H-indazole
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
- Product number
- OR14098
- Product name
- 3-Chloro-6-nitro-1H-indazole
- Packaging
- 1g
- Price
- $64
- Updated
- 2021/12/16
- Product number
- 4H55-5-Y5
- Product name
- 3-Chloro-6-nitro-1H-indazole
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
3-CHLORO-6-NITRO (1H)INDAZOLE Chemical Properties,Usage,Production
Chemical Properties
Yellow solid
Synthesis
7597-18-4
50593-68-5
General procedure for the synthesis of 3-chloro-6-nitro-1H-indazole from 6-nitro-1H-indazole: 6-nitro-1H-indazole (5.0 g, 31 mmol) was added to an aqueous (150 mL) solution of sodium hydroxide (5.0 g), and the mixture was heated until a red color solution formed. The reaction mixture was cooled in an ice water bath for 15 minutes, followed by the slow addition of sodium hypochlorite solution (60 mL, 5.25%, 45 mmol). The reaction mixture was stirred continuously at 0 °C for 5 h. Upon completion of the reaction, the pH was adjusted with dilute hydrochloric acid to 7. The reaction mixture was extracted with ethyl acetate, the organic layers were combined and washed with distilled water, followed by concentration of the organic phase under reduced pressure. The residue was purified by fast column chromatography to afford the target product 3-chloro-6-nitro-1H-indazole (5.5 g, 92% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 7.93 (m, 1H), 8.02 (m, 1H), 8.50 (m, 1H), 14.01 (s, 1H); the mass spectrum (DCI/NH3) showed m/z 197 [M+H]+.
References
[1] Patent: US2005/277638, 2005, A1. Location in patent: Page/Page column 49
[2] Journal of Chemical Research, Miniprint, 1990, # 11, p. 2601 - 2615
[3] Heterocycles, 1995, vol. 41, # 3, p. 487 - 496
[4] Justus Liebigs Annalen der Chemie, 1927, vol. 451, p. 285,302
[5] Justus Liebigs Annalen der Chemie, 1927, vol. 451, p. 285,302
3-CHLORO-6-NITRO (1H)INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-CHLORO-6-NITRO (1H)INDAZOLE manufacturers
- Product
- 3-CHLORO-6-NITRO (1H)INDAZOLE 50593-68-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- 200KG
- Release date
- 2018-08-15