SOMATOSTATIN 28, CYCLIC
- Product Name
- SOMATOSTATIN 28, CYCLIC
- CAS No.
- 73032-94-7
- Chemical Name
- SOMATOSTATIN 28, CYCLIC
- Synonyms
- 28)-disulfide;Cyclic somatostatin-28;SOMATOSTATIN 28, CYCLIC;Somatostatin 28, ≥97% (HPLC);Somatostatin 28 TFA,TFA salt;M.W. 3148.60 C137H207N41O39S3;SOMATOSTATIN 28, CYCLIC USP/EP/BP;Somatostatin-28 (sheep, human rat mouse);Somatostatin-28 (sheep reduced) cyclic (17-28)-disulfide;H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH
- CBNumber
- CB0679871
- Molecular Formula
- C137H207N41O39S3
- Formula Weight
- 3148.56
- MOL File
- 73032-94-7.mol
SOMATOSTATIN 28, CYCLIC Property
- RTECS
- WF8755700
- storage temp.
- −20°C
- form
- Solid
- color
- White to off-white
- Water Solubility
- water: 1mg/mL, clear, colorless
- CAS DataBase Reference
- 73032-94-7
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- S6135
- Product name
- Somatostatin 28
- Purity
- ≥97%(HPLC)
- Packaging
- 0.1mg
- Price
- $250.8
- Updated
- 2025/07/31
- Product number
- S6135
- Product name
- Somatostatin 28
- Purity
- ≥97%(HPLC)
- Packaging
- 0.5mg
- Price
- $743
- Updated
- 2025/07/31
- Product number
- S6135
- Product name
- Somatostatin 28
- Purity
- ≥97% (HPLC)
- Packaging
- 1mg
- Price
- $1290
- Updated
- 2025/07/31
- Product number
- PEP0003392
- Product name
- SOMATOSTATIN 28
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $650.27
- Updated
- 2021/12/16
SOMATOSTATIN 28, CYCLIC Chemical Properties,Usage,Production
Uses
Somatostatin 28 has been used to study the effects of somatostatin in regulating hepatic growth hormone sensitivity. It has also been used to study its effects on insulin-like growth factor-I receptor expression in the gills of Oncorhynchus mykiss (a teleost fish).
General Description
The SST gene is mapped to human chromosome 3q27.3. Both SST-14 and SST-28 are cyclic peptide.
Hazard
A poison.
Biochem/physiol Actions
Somatostatin plays an important role in regulating the metabolism of other hormones such as growth hormone, insulin, IGF-1 (insulin-like growth factor 1), glucagon, glucagon-like peptide and gastrin. Somatostatin has both regulatory and inhibitory functions. It retards gastrointestinal motility and gallbladder contraction, suppresses gut exocrine secretion and reduces epithelial proliferation. Somatostatin is associated with intestinal nutrient absorption and blood flow regulation. This peptide hormone is believed to inhibit cell proliferation and promote apoptosis. Somatostatin acts as a neurotransmitter and neuromodulator, and is also associated in maintaining water balance.
in vivo
Somatostatin-28 (sheep) (1.1 pmol/kg/min; i.v. via a jugular catheter; 15 min) inhibits insulin secretion induced by 25 μg/kg/min glucose in sheep[2].
| Animal Model: | Finn-Dorset Horn cross bred sheep (2-5 years old, 70-75 kg)[2] |
| Dosage: | 1.1 pmol/kg/min for 15 min, with or without 25 μg/kg/min glucose; |
| Administration: | Intravenous injection via a jugular catheter; |
| Result: | Significantly inhibited insulin secretion, resulted serum concentrations decreasing from about 200 to 150 pmol/L. |
IC 50
SSTR5
SOMATOSTATIN 28, CYCLIC Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SOMATOSTATIN 28, CYCLIC manufacturers
- Product
- SOMATOSTATIN 28, CYCLIC 73032-94-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-11
- Product
- SOMATOSTATIN 28, CYCLIC 73032-94-7
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-18