ChemicalBook > CAS DataBase List > 2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE

2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE

Product Name
2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE
CAS No.
532967-21-8
Chemical Name
2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE
Synonyms
CAS:532967-21-8;3,5-Difluoro-4-formylphenol;6-difluoro-4-hydroxybenzaldehyde;2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE;Benzaldehyde, 2,6-difluoro-4-hydroxy-;2,6-Difluoro-4-hydroxybenzaldehyde,95%;2,6-Difluoro-4-hydroxybenzaldehyde 98%;2,6-Difluoro-4-hydroxybenzaldehyde ,97%;Benzaldehyde, 2,6-difluoro-4-hydroxy- (9CI);2,6-difluoro-4-hydroxybenzaldehyde2,6-difluoro-4-hydroxybenzaldehyde
CBNumber
CB0687128
Molecular Formula
C7H4F2O2
Formula Weight
158.1
MOL File
532967-21-8.mol
More
Less

2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE Property

Melting point:
179-182℃
Boiling point:
252.6±35.0 °C(Predicted)
Density 
1.464±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder
pka
5.80±0.23(Predicted)
color 
Off-white to cream
Sensitive 
Air Sensitive
CAS DataBase Reference
532967-21-8
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
20-36/37/38
Safety Statements 
22-36/37/39-45
Hazard Note 
Irritant
HS Code 
29124990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D447438
Product name
2,6-Difluoro-4-hydroxybenzaldehyde
Packaging
1g
Price
$125
Updated
2021/12/16
Apolloscientific
Product number
PC9940
Product name
2,6-Difluoro-4-hydroxybenzaldehyde
Purity
98%
Packaging
250mg
Price
$25
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-3-35
Product name
2,6-Difluoro-4-hydroxybenzaldehyde
Packaging
250mg
Price
$40
Updated
2021/12/16
Apolloscientific
Product number
PC9940
Product name
2,6-Difluoro-4-hydroxybenzaldehyde
Purity
98%
Packaging
1g
Price
$80
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-3-35
Product name
2,6-Difluoro-4-hydroxybenzaldehyde
Packaging
1g
Price
$128
Updated
2021/12/16
More
Less

2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

Brown to red powder

Synthesis

68-12-2

532967-21-8

General procedure for the synthesis of 2,6-difluoro-4-hydroxybenzaldehyde from N,N-dimethylformamide: At -78 °C, sec-butyllithium (1.3 M cyclohexane solution, 53 mL, 69.3 mmol) was slowly added to intermediates 19,1-(tert-butyldimethylsilyl)oxy-3,5-difluorobenzene (15.3 g, 62.6 mmol) and TMEDA (10.5 mL, 69.3 mmol) in a solution of tetrahydrofuran (200 mL) and stirred for 30 min at a maintained temperature of -78 °C. Subsequently, DMF (5.33 mL, 69.3 mmol) was added at the same temperature and stirring was continued for 1.5 hours. After the reaction was completed, 10% aqueous hydrochloric acid was added to adjust the pH to 4-5 (~200 mL) and then stirred at room temperature for 12 hours. The aqueous layer was extracted with ethyl acetate (200 mL) and the organic layer was separated. The organic layer was washed sequentially with saturated aqueous sodium bicarbonate, added sodium bicarbonate followed by water, and then adjusted the pH to 3-4 with hydrochloric acid, separated the organic layer, washed with brine, dried with anhydrous sodium sulfate, and finally evaporated in vacuum to obtain 2,6-difluoro-4-hydroxybenzaldehyde (9.7 g, 97% yield, 61.3 mmol) as a white solid.1H NMR (DMSO-d6) data: δ 11.54 (br.s, 1H, OH), 10.00 (s, 1H, CHO), 6.50-6.57 (m, 2H, Ar-H).

References

[1] Patent: WO2006/136924, 2006, A1. Location in patent: Page/Page column 136-137

2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

3,5-Difluorophenol Potassium hydroxide Phosphorus oxitrichloride Chloroform Ethyl acetate PETROLEUM ETHER

Preparation Products

More
Less

2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE Suppliers

China 115 Europe 1 Germany 1 India 2 Italy 1 United Kingdom 8 United States 12 Global 140
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Beijing Eternalchem Co,. Ltd.
Tel
010-59484199 18611897322
Email
sales@eternalchem.com
Country
China
ProdList
4383
Advantage
60
ChemShuttle, Inc.
Tel
0510-83588313-811 18800520310
Email
sales@chemshuttle.com
Country
China
ProdList
2999
Advantage
62
Shanghai yirong biology science and technology co., ltd
Tel
18049974220
Fax
+86 (21) 51062076
Email
3060526242@qq.com
Country
China
ProdList
995
Advantage
60
Tianjin Derchemist Science & Technology Co., Ltd.
Tel
22-58627059 13920586291
Fax
022-58620305
Email
zdcomcon@126.com
Country
China
ProdList
3829
Advantage
50
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai ShiXian Chemical Technology Co., Ltd.
Tel
18681884732
Fax
021-51632502
Email
2245256225@qq.com
Country
China
ProdList
1729
Advantage
50
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Changzhou Anxuan Chemical, Co., Ltd.
Tel
13912302692 13912302692;
Fax
0519-88064678
Email
sales@anxuanchem.com
Country
China
ProdList
4828
Advantage
58
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Shanghai Kahn Pharmaceutical Co., Ltd.
Tel
021-34979681; 17701870669
Fax
021-34979681
Email
41513101@qq.com
Country
China
ProdList
1785
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
sales@chemwill.com
Country
China
ProdList
1974
Advantage
58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Suzhou JingTong Pharmaceutical Co., Ltd.
Tel
13675155016
Fax
18912765016
Email
tongtf110@sina.com
Country
China
ProdList
963
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9722
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Shanghai Scochem Technology Co., Ltd.
Tel
021-33758897
Email
sales@scochem.com
Country
China
ProdList
1596
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
wuhan Dekray Biomedical Technology Co.,Ltd
Tel
027-69573188 18221423799
Email
1503407886@qq.com
Country
China
ProdList
1439
Advantage
58
Allfluoro pharmaceutical co. ltd.
Tel
+86-400-0216110 +86-15958047586
Fax
0086-21-33275002
Email
sales@allfluoro.com
Country
China
ProdList
11385
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
+8615838112936
Email
alfa10@alfachem.cn
Country
China
ProdList
12921
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Blocksynth Pharmaceutical Technology Co.,Ltd
Tel
0086-19817745290; +8619817745290
Email
bd@blocksynth.com
Country
China
ProdList
5661
Advantage
58
Win-Win chemical CO., Limited
Tel
+86-0086-577-64498589 +86-15355981851
Fax
0086-577-56994596
Email
sales@win-winchemical.com
Country
China
ProdList
14359
Advantage
58
Hebei Chuanghai Biotechnology Co., Ltd
Tel
+8615350571055
Fax
whatapp+8619930503282
Email
Sibel@chuanghaibio.com
Country
China
ProdList
8768
Advantage
58
Henan Lien Chemical Products Co., Ltd.
Tel
0371-63357898 15378766539
Email
535046669@qq.com
Country
China
ProdList
4641
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
More
Less

View Lastest Price from 2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE 532967-21-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Shaanxi Dideu Medichem Co. Ltd
Product
2,6-Difluoro-4-hydroxybenzaldehyde 532967-21-8
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15
Career Henan Chemical Co
Product
2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE 532967-21-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-07-03

532967-21-8, 2,6-DIFLUORO-4-HYDROXYBENZALDEHYDERelated Search:

2,6-Difluoro-4-hydroxybenzoic acid 2,3,5,6-Tetrafluoro-4-hydroxy-benzoic acid 2,6-DIFLUORO-4-METHOXYBENZOIC ACID 2,6-DIFLUORO-4-METHOXYBENZALDEHYDE 2',6'-DIFLUORO-4'-METHOXYACETOPHENONE 3,5-DIFLUORO-4-HYDROXYBENZALDEHYDE,3,5-Difluoro-4-hydroxybenzaldehyde 97%,3,5-Difluoro-4-hydroxybenzaldehyde97% 2,3-Difluoro-4-hydroxybenzaldehyde97% 2,6-DIFLUORO-4-METHOXYBENZAMIDE 2,3,5,6-TETRAFLUORO-4-HYDROXYBENZOIC ACID HYDRATE 4-ACETOXY-2,3,5,6-TETRAFLUOROBENZOIC ACID 3,6-DIFLUORO-2-HYDROXYBENZALDEHYDE 2,3-DIFLUORO-6-HYDROXYBENZALDEHYDE 4,5-DIFLUORO-2-HYDROXYBENZALDEHYDE 2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE OXIME 2,5-DIFLUORO-4-HYDROXYBENZALDEHYDE 2,6-DIFLUORO-3-HYDROXYBENZALDEHYDE 3,4-DIFLUORO-2-HYDROXYBENZALDEHYDE 2,6-DIFLUORO-4-METHOXYBENZOYL CHLORIDE

  • 2,6-DIFLUORO-4-HYDROXYBENZALDEHYDE
  • Benzaldehyde, 2,6-difluoro-4-hydroxy- (9CI)
  • 3,5-Difluoro-4-formylphenol
  • 6-difluoro-4-hydroxybenzaldehyde
  • 2,6-Difluoro-4-hydroxybenzaldehyde ,97%
  • 2,6-difluoro-4-hydroxybenzaldehyde2,6-difluoro-4-hydroxybenzaldehyde
  • 2,6-Difluoro-4-hydroxybenzaldehyde 98%
  • Benzaldehyde, 2,6-difluoro-4-hydroxy-
  • 2,6-Difluoro-4-hydroxybenzaldehyde,95%
  • CAS:532967-21-8
  • 532967-21-8
  • ALDEHYDE
  • ALCOHOL
  • HALIDE
  • Aromatic Aldehydes & Derivatives (substituted)