Uses
ChemicalBook > CAS DataBase List > Diethyl 2,5-dibromohexanedioate

Diethyl 2,5-dibromohexanedioate

Uses
Product Name
Diethyl 2,5-dibromohexanedioate
CAS No.
869-10-3
Chemical Name
Diethyl 2,5-dibromohexanedioate
Synonyms
DIETHYL MESO-2,5-DIBROMOADIPATE;2,5-Dib;AKOS 2004;meso-2,5-dibromoadipate;iethyl 2,5-dibromoadipate;Diethyl 2,5-dibromoadipate;Diethyl a'd-dibromoadipate;Diethylmeso-dibromoadipate;DIETHYL A,A'-DIBROMOADIPATE;Diethyl α,α'-Dibromoadipate
CBNumber
CB0687810
Molecular Formula
C10H16Br2O4
Formula Weight
360.04
MOL File
869-10-3.mol
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Diethyl 2,5-dibromohexanedioate Property

Melting point:
65-67 °C (lit.)
Boiling point:
134°C/0.5mmHg(lit.)
Density 
1.7082 (rough estimate)
refractive index 
1.5010 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DCM
form 
Solid
color 
Brown
Sensitive 
Light Sensitive
InChI
InChI=1S/C10H16Br2O4/c1-3-15-9(13)7(11)5-6-8(12)10(14)16-4-2/h7-8H,3-6H2,1-2H3
InChIKey
UBCNJHBDCUBIPB-UHFFFAOYSA-N
SMILES
C(OCC)(=O)C(Br)CCC(Br)C(OCC)=O
CAS DataBase Reference
869-10-3(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34-36/37
Safety Statements 
26-27-28-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29171900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
347191
Product name
Diethyl meso-2,5-dibromoadipate
Purity
98%
Packaging
5g
Price
$16.68
Updated
2024/03/01
Sigma-Aldrich
Product number
347191
Product name
Diethyl meso-2,5-dibromoadipate
Purity
98%
Packaging
25g
Price
$162
Updated
2024/03/01
TCI Chemical
Product number
D3965
Product name
Diethyl 2,5-Dibromoadipate
Purity
>98.0%(GC)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
D3965
Product name
Diethyl 2,5-Dibromoadipate
Purity
>98.0%(GC)
Packaging
25g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
H26347
Product name
Diethyl meso-2,5-dibromoadipate, 98%
Packaging
5g
Price
$46.65
Updated
2024/03/01
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Diethyl 2,5-dibromohexanedioate Chemical Properties,Usage,Production

Uses

Diethyl α,α'-Dibromoadipate is an intermediate in the synthesis of Muconic Acid, a metabolite found in urine found in workers with prolonged exposure to Benzene.

Uses

Diethyl meso-2,5-dibromoadipate may be employed as difunctional initiator during n-butyl acrylate (n-BuA) polymerization, leading to α,ω-bromo-poly(n-BuA) having narrow molecular weight distribution. It was also used:

  • as bifunctional atom transfer radical polymerization (ATRP) initiator
  • as initiator during the solution polymerization of octadecyl ester ether dimer by ATRP
  • in the synthesis of diethyl 2,5-diazidoadipate

Uses

Diethyl 2,5-dibromohexanedioate can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

General Description

Diethyl meso-2,5-dibromoadipate reacts with N-methylallylamine in the presence of potassium carbonate to yield two diastereomers of diethyl 2-allyl-N-methylpyrrolidine-2,5-dicarboxylate.

Synthesis


meso-2,5-Dibromo-hexanedioic acid diethyl ester JS-053: Adipic acid (795 g, 3.93 mol) was added in small portions to thionylchloride (980 mL, 5.44 mol) for 2 hours at 65 degC. This suspension was mechanically stirred and heated on an oil bath for an additional 3.5 hours at 70 degC, until the gas evolution was finished. To the UV lamp irradiated (2x 120W) solution was added dropwise bromine (664 mL, 12.48 mol) for 7 hours at 85-95 degC. After finishing of absorption of bromine, the reaction mixture was cooled down, poured into ethanol (4000 mL, 96 %) at -5 degC and mechanically stirred for an additional 1 week at rt. Crystals were filtered off and washed with ethanol (2x 300 mL, 96 %) to afford meso-2,5-dibromo-hexanedioic acid diethyl ester (JS-053, 1343 g, 3.73 mol, yield 95 %, GC 98 %, mp 66 degC/lit.

Diethyl 2,5-dibromohexanedioate Preparation Products And Raw materials

Raw materials

Preparation Products

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Diethyl 2,5-dibromohexanedioate Suppliers

Baiyin letianyuan chemical co., LTD
Tel
0943-8627236 18194330484
Fax
0943-8627236
Email
2919219720@qq.com
Country
China
ProdList
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58
chengqiaotech.ltd
Tel
18105338618
Email
zbcqyh@126.com
Country
China
ProdList
294
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58
shanghai huiyu
Tel
15380804498
Email
330062898@qq.com
Country
China
ProdList
198
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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61
shanghai science Bio-Pharmceutical.co,ltd.
Tel
021-021-57872719 13761402923
Fax
02157872719
Email
245662540@qq.com
Country
China
ProdList
309
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View Lastest Price from Diethyl 2,5-dibromohexanedioate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Diethyl 2,5-dibromohexanedioate 869-10-3
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-11-29
Hebei Weibang Biotechnology Co., Ltd
Product
Diethyl 2,5-dibromohexanedioate 869-10-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Diethyl 2,5-dibromohexanedioate 869-10-3
Price
US $65.00-650.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-08

869-10-3, Diethyl 2,5-dibromohexanedioateRelated Search:


  • DIETHYL 2,5-DIBROMOHEXANEDIOATE
  • DIETHYL-ALPHA,ALPHA'-DIBROMOADIPATE
  • DIETHYL A,A'-DIBROMOADIPATE
  • AKOS 2004
  • 2,5-Dibromohexanedioic acid diethyl ester
  • Diethylmeso-dibromoadipate
  • Diethyl a'd-dibromoadipate
  • Diethyl 2,5-dibromoadipate
  • meso-2,5-dibromoadipicaciddiethylester
  • Diethyl 2,5-dibromohexane-1,6-dioate
  • Hexanedioic acid, 2,5-dibroMo-, 1,6-diethyl ester
  • Diethyl Meso-2,5-dibroMoadipate 98%
  • 2,5-Dibromoadipic Acid Diethyl Ester
  • 2,5-Dib
  • DIETHYL MESO-2,5-DIBROMOADIPATE
  • 2,5-dibromo-2,3-diethylhexanedioate
  • iethyl 2,5-dibromoadipate
  • Diethyl2,5-Dibromoadipate&gt
  • Diethyl α,α'-Dibromoadipate
  • meso-2,5-dibromoadipate
  • diethyl (2S,5R)-2,5-dibromohexanedioate
  • 2, 5-diethyl dibromoadipate
  • 869-10-3 Diethyl 2,5-dibromohexanedioate
  • 2,5-Dibromadipic acid diethyl ester
  • diethyl 2,5-dibromohexanedioat
  • Diethyl α,α'-Dibromoadipate
  • 869-10-3
  • -CH2CHBrCO2C2H52
  • C10H16Br2O4
  • Building Blocks
  • C10 to C11
  • Carbonyl Compounds
  • Organic Building Blocks
  • Esters
  • Aliphatics
  • Esters
  • C10 to C11
  • Carbonyl Compounds