2,5-Dibromopyrazine
Application- Product Name
- 2,5-Dibromopyrazine
- CAS No.
- 23229-26-7
- Chemical Name
- 2,5-Dibromopyrazine
- Synonyms
- 5-Dibromopyrazine;2,5-DIBROMOPYRAZINE;PYRAZINE,2,5-DIBROMO;2,5-bisbromopyrazine;2,5-Dibromopyrazine>2,5-Dibromopyrazine 95% (GC);2,5-Dibromopyrazine ISO 9001：2015 REACH;3,6-Dibromopyrazine, 2,5-Dibromo-1,4-diazine
- CBNumber
- CB0701358
- Molecular Formula
- C4H2Br2N2
- Formula Weight
- 237.88
- MOL File
- 23229-26-7.mol
2,5-Dibromopyrazine Property
- Melting point:
- 45.0 to 49.0 °C
- Boiling point:
- 234.0±35.0 °C(Predicted)
- Density
- 2.197
- Flash point:
- 95℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- -4.28±0.10(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- InChI
- InChI=1S/C4H2Br2N2/c5-3-1-7-4(6)2-8-3/h1-2H
- InChIKey
- KIYKHEOWZLJZSB-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=C(Br)N=C1
- CAS DataBase Reference
- 23229-26-7
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 796603
- Product name
- 2,5-Dibromopyrazine
- Purity
- 95% (GC)
- Packaging
- 1G
- Price
- $45.3
- Updated
- 2025/07/31
- Product number
- D4323
- Product name
- 2,5-Dibromopyrazine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $24
- Updated
- 2025/07/31
- Product number
- D4323
- Product name
- 2,5-Dibromopyrazine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $69
- Updated
- 2025/07/31
- Product number
- D425995
- Product name
- 2,5-Dibromopyrazine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D425995
- Product name
- 2,5-Dibromopyrazine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
2,5-Dibromopyrazine Chemical Properties,Usage,Production
Application
2,5-Dibromopyrazine is a common organic synthon that can serve as a molecular skeleton in the synthesis of bioactive molecules.
Synthesis
5-bromopyrazin-2-amine (3 g, 17.241 mmol) and bromine (8.2 g, 51.729 mmol) were added to aq. HBr solution at -15° C. Aq. solution of sodium nitrite (2.97 g, 43.0103 mmol) was then added to the mixture over a period of 1 h at -10° C. keeping the internal temperature below 5° C. during addition and stirred for 1 h at 0° C. Progress of reaction was monitored by TLC. After reaction completion reaction mass neutralised with 40percent NaOH solution and extracted with diethyl ether. The organic layer was dried over sodium sulphate and concentrated under reduced pressure (below 30° C.) to yield 2,5-Dibromopyrazine (1 g, 24.4percent) as brown oil.
References
[1] Patent: US2017/291910, 2017, A1. Location in patent: Paragraph 0592-0594
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 2798
[3] Chemistry - A European Journal, 2010, vol. 16, # 19, p. 5645 - 5660
[4] Patent: WO2004/56369, 2004, A1. Location in patent: Page/Page column 24-25
2,5-Dibromopyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,5-Dibromopyrazine manufacturers
- Product
- 2,5-Dibromopyrazine 23229-26-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.4%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26
- Product
- 2,5-Dibromopyrazine 23229-26-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 800 tons
- Release date
- 2020-04-28
- Product
- 2,5-Dibromopyrazine 23229-26-7
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-23