ChemicalBook > CAS DataBase List > 3,6-dibromopyrazin-2-amine

3,6-dibromopyrazin-2-amine

Product Name
3,6-dibromopyrazin-2-amine
CAS No.
957230-70-5
Chemical Name
3,6-dibromopyrazin-2-amine
Synonyms
3,6-DIBROMOPYRAZIN-2-AMINE;3,6-dibromo-2-pyrazinamine;3,6-didroMopyrazin-2-aMine;2-aMino-3,6-DibroMopyrazine;2,5-Dibromo-3-aminopyrazine;3,6-Dibromopyrazine-2-amine;3-Amino-2,5-dibromopyrazine;2-Pyrazinamine, 3,6-dibromo-;3,6-Dibromopyrazin-2-ylamine;3,6-DIBROMOPYRAZIN-2-AMIN...
CBNumber
CB42455291
Molecular Formula
C4H3Br2N3
Formula Weight
252.89
MOL File
957230-70-5.mol
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3,6-dibromopyrazin-2-amine Property

Boiling point:
314℃
Density 
2.287
Flash point:
144℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
0.05±0.10(Predicted)
Water Solubility 
Slightly soluble in water.
InChI
InChI=1S/C4H3Br2N3/c5-2-1-8-3(6)4(7)9-2/h1H,(H2,7,9)
InChIKey
ZEDFFSRZLCREEN-UHFFFAOYSA-N
SMILES
C1(N)=NC(Br)=CN=C1Br
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H59185
Product name
2-Amino-3,6-dibromopyrazine, 95%
Packaging
1g
Price
$337
Updated
2022/04/27
Alfa Aesar
Product number
H59185
Product name
2-Amino-3,6-dibromopyrazine, 95%
Packaging
250mg
Price
$105
Updated
2021/12/16
TRC
Product number
D424740
Product name
3,6-Dibromopyrazin-2-amine
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
068899
Product name
3,6-Dibromopyrazin-2-amine
Purity
>95%
Packaging
250mg
Price
$171
Updated
2021/12/16
Matrix Scientific
Product number
068899
Product name
3,6-Dibromopyrazin-2-amine
Purity
>95%
Packaging
1g
Price
$429
Updated
2021/12/16
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3,6-dibromopyrazin-2-amine Chemical Properties,Usage,Production

Uses

It is used as a pharmaceutical intermediate.

Synthesis

Diphenylphosphoryl azide (488 mg, 1.77 mmol) and triethylamine (180 mg, 1.77 mmol) were added to a solution of the acid (500 mg, 1.77 mmol) in tert-butanol (12 mL). The reaction mixture was stirred at reflux for 18 h and then quenched with water. The volatiles were removed under reduced pressure. The residue was dissolved in 4:1 TFA/DCM (5 mL) and stirred at rt for 1 h. The volatiles were removed under reduced pressure. The residue was dissolved in DCM and washed with 1N aq. NaOH. The combined organic extracts were dried (Na2SO4), filtered and concentrated. The crude residue was purified by SiO2 chromatography eluting with an EtOAc/hexane gradient to afford 3,6-dibromopyrazin-2-amine 120 mg (27%) of bromoanisol as a colorless oil. MS m/z (ES): 253 (M+H)+.

3,6-dibromopyrazin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,6-dibromopyrazin-2-amine Suppliers

China 99 India 3 United Kingdom 2 United States 7 Global 111
Kohn & Shawn Pharmatech Co.,Ltd
Tel
0931-4190454 13893344397
Fax
+86-931-8506154
Email
sales@kyxpharma.com
Country
China
ProdList
290
Advantage
55
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
shanghai Rainbow MediTech.Co.Ltd.
Tel
21-021-64968085,64968086-5815,5812 13918693646
Fax
+86 21 64968087
Email
bd@rainbowpharma.cn
Country
China
ProdList
976
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65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
976
Advantage
62
Dtchem Laboratories,（Gan Su）Co.,Ltd.
Tel
18993966060
Fax
0943-8288977
Email
sales@techbiochem.com
Country
China
ProdList
894
Advantage
61
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View Lastest Price from 3,6-dibromopyrazin-2-amine manufacturers

Career Henan Chemical Co
Product
3,6-DIBROMOPYRAZIN-2-AMINE 957230-70-5
Price
US $2.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2020-01-07

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