3,6-dibromopyrazin-2-amine
- Product Name
- 3,6-dibromopyrazin-2-amine
- CAS No.
- 957230-70-5
- Chemical Name
- 3,6-dibromopyrazin-2-amine
- Synonyms
- 3,6-DIBROMOPYRAZIN-2-AMINE;3,6-dibromo-2-pyrazinamine;3,6-didroMopyrazin-2-aMine;2-aMino-3,6-DibroMopyrazine;2,5-Dibromo-3-aminopyrazine;3,6-Dibromopyrazine-2-amine;3-Amino-2,5-dibromopyrazine;2-Pyrazinamine, 3,6-dibromo-;3,6-Dibromopyrazin-2-ylamine;3,6-DIBROMOPYRAZIN-2-AMIN...
- CBNumber
- CB42455291
- Molecular Formula
- C4H3Br2N3
- Formula Weight
- 252.89
- MOL File
- 957230-70-5.mol
3,6-dibromopyrazin-2-amine Property
- Boiling point:
- 314℃
- Density
- 2.287
- Flash point:
- 144℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 0.05±0.10(Predicted)
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C4H3Br2N3/c5-2-1-8-3(6)4(7)9-2/h1H,(H2,7,9)
- InChIKey
- ZEDFFSRZLCREEN-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(Br)=CN=C1Br
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H59185
- Product name
- 2-Amino-3,6-dibromopyrazine, 95%
- Packaging
- 1g
- Price
- $337
- Updated
- 2022/04/27
- Product number
- H59185
- Product name
- 2-Amino-3,6-dibromopyrazine, 95%
- Packaging
- 250mg
- Price
- $105
- Updated
- 2021/12/16
- Product number
- D424740
- Product name
- 3,6-Dibromopyrazin-2-amine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 068899
- Product name
- 3,6-Dibromopyrazin-2-amine
- Purity
- >95%
- Packaging
- 250mg
- Price
- $171
- Updated
- 2021/12/16
- Product number
- 068899
- Product name
- 3,6-Dibromopyrazin-2-amine
- Purity
- >95%
- Packaging
- 1g
- Price
- $429
- Updated
- 2021/12/16
3,6-dibromopyrazin-2-amine Chemical Properties,Usage,Production
Uses
It is used as a pharmaceutical intermediate.
Synthesis
Diphenylphosphoryl azide (488 mg, 1.77 mmol) and triethylamine (180 mg, 1.77 mmol) were added to a solution of the acid (500 mg, 1.77 mmol) in tert-butanol (12 mL). The reaction mixture was stirred at reflux for 18 h and then quenched with water. The volatiles were removed under reduced pressure. The residue was dissolved in 4:1 TFA/DCM (5 mL) and stirred at rt for 1 h. The volatiles were removed under reduced pressure. The residue was dissolved in DCM and washed with 1N aq. NaOH. The combined organic extracts were dried (Na2SO4), filtered and concentrated. The crude residue was purified by SiO2 chromatography eluting with an EtOAc/hexane gradient to afford 3,6-dibromopyrazin-2-amine 120 mg (27%) of bromoanisol as a colorless oil. MS m/z (ES): 253 (M+H)+.
3,6-dibromopyrazin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
3,6-dibromopyrazin-2-amine Suppliers
View Lastest Price from 3,6-dibromopyrazin-2-amine manufacturers
- Product
- 3,6-DIBROMOPYRAZIN-2-AMINE 957230-70-5
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 100kg
- Release date
- 2020-01-07