2-Bromo-4-chloro-1-iodobenzene
- Product Name
- 2-Bromo-4-chloro-1-iodobenzene
- CAS No.
- 31928-44-6
- Chemical Name
- 2-Bromo-4-chloro-1-iodobenzene
- Synonyms
- 1-Iodo-2-bromo-4-chlorobenzene;2-Bromo-1-iodo-4-chlorobenzene;2-BROMO-4-CHLORO-1-IODOBENZENE;Benzene, 2-bromo-4-chloro-1-iodo-;2-Bromo-4-chloro-1-iodobenzene >
- CBNumber
- CB0691356
- Molecular Formula
- C6H3BrClI
- Formula Weight
- 317.35
- MOL File
- 31928-44-6.mol
2-Bromo-4-chloro-1-iodobenzene Property
- Melting point:
- 32-35℃
- Boiling point:
- 279℃
- Density
- 2.272
- Flash point:
- 123℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to lump to clear liquid
- color
- White or Colorless to Yellow
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C6H3BrClI/c7-5-3-4(8)1-2-6(5)9/h1-3H
- InChIKey
- CXHXFDQEFKFYQJ-UHFFFAOYSA-N
- SMILES
- C1(I)=CC=C(Cl)C=C1Br
- CAS DataBase Reference
- 31928-44-6
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B4243
- Product name
- 2-Bromo-4-chloro-1-iodobenzene
- Packaging
- 5G
- Price
- $43
- Updated
- 2025/07/31
- Product number
- B4243
- Product name
- 2-Bromo-4-chloro-1-iodobenzene
- Packaging
- 25G
- Price
- $123
- Updated
- 2025/07/31
- Product number
- B682458
- Product name
- 2-Bromo-4-chloro-1-iodobenzene
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J95091
- Product name
- 2-Bromo-4-chloroiodobenzene
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- J95091
- Product name
- 2-Bromo-4-chloroiodobenzene
- Packaging
- 5g
- Price
- $15
- Updated
- 2021/12/16
2-Bromo-4-chloro-1-iodobenzene Chemical Properties,Usage,Production
Synthesis
2-Bromo-4-chloroaniline (10 g, 48 mmol) was suspended in hydrochloric acid water (50 mL of concentrated hydrochloric acid and 35 mL of water), and the suspension was cooled on a dry ice/methanol bath at -15°C. A sodium nitrite aqueous solution (3.6 g, 52 mmol, 1. 1 eq. /20 mL) was gradually added dropwise to it over 20 minutes, and the mixture was stirred from -15°C to 0°C for 30 minutes, thereby preparing a diazonium salt. The reaction solution was gradually added dropwise to a potassium iodide aqueous solution (73 g, 0.44 mol, 9 eq. /220 mL) at room temperature for 10 minutes. The reaction mixture was stirred at room temperature for 6 hours and then allowed to stand overnight. Dichloromethane (200 mL) was added to the reaction mixture, and subsequently, sodium hydrogensulfite (2 g) was added, deactivating the generated iodine. An organic layer was aliquoted, washed with a 10 % sodium hydrogensulfite aqueous solution (100 mL) and saturated salt water (30 mL) and dried over anhydrous magnesium sulfate. The solvent was then distilled off to obtain a red liquid. This was purified using column chromatography (silica gel/hexane) to obtain a white needle crystal 2-Bromo-4-chloro-1-iodobenzene (12.4 g, 81 %).
References
[1] Patent: EP2316816, 2011, A1. Location in patent: Page/Page column 21
[2] Chemistry - A European Journal, 2018, vol. 24, # 55, p. 14622 - 14626
[3] Angewandte Chemie - International Edition, 2008, vol. 47, # 5, p. 888 - 890
[4] Angewandte Chemie - International Edition, 2008, vol. 47, # 9, p. 1726 - 1728
[5] Journal of Organic Chemistry, 1987, vol. 52, # 5, p. 748 - 753
2-Bromo-4-chloro-1-iodobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-4-chloro-1-iodobenzene manufacturers
- Product
- 2-Bromo-4-chloro-1-iodobenzene 31928-44-6
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 2-Bromo-4-chloro-1-iodobenzene 31928-44-6
- Price
- US $35.00-25.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 Ton
- Release date
- 2023-11-09
- Product
- 2-BROMO-4-CHLORO-1-IODOBENZENE 31928-44-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25