EXO1

Product Name: EXO1
CAS No.: 75541-83-2
Chemical Name: EXO1
Synonyms: EXO1;EOX 1;NSC 214045;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-Fluoro-benzoylami;Exo 1 >=98% (HPLC), solid;Exo1 - CAS 75541-83-2 - Calbiochem;Exo1,inhibit,Exo-1,Exo 1,Inhibitor;Methyl 2-(4-fluorobenzamido)benzoate
CBNumber: CB0713355
Molecular Formula: C15H12FNO3
Formula Weight: 273.26
MOL File: 75541-83-2.mol

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EXO1 Property

storage temp.: +2C to +8C
solubility: DMSO: 19 mg/mL, soluble
form: solid
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E8280
Product name: Exo 1
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $69.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 341220
Product name: Exo1
Packaging: 25mg
Price: $182
Updated: 2024/03/01

Cayman Chemical

Product number: 18455
Product name: Exo 1
Purity: ≥99%
Packaging: 10mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 18455
Product name: Exo 1
Purity: ≥99%
Packaging: 50mg
Price: $324
Updated: 2024/03/01

Sigma-Aldrich

Product number: E8280
Product name: Exo 1
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $244
Updated: 2024/03/01

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EXO1 Chemical Properties,Usage,Production

Uses

Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 μM). It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.

Uses

Exo 1 acts as a cell-permeable reverse inhibitor of exocytosis. Potential anti-inflammatory activity.

Uses

Exo 1 has been used as a component of the BRB80 buffer to study coat protein 1 (COPI)-mediated membrane trafficking. It has also been used as a Golgi inhibitor to study its effects on the long?interspersed?nuclear?element-1 (L1) retrotransposition.

Definition

ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.

Biochem/physiol Actions

Exo 1 is a cell-permeable methylanthranilate analog that promotes the release of adenosine diphosphate (ADP)-ribosylation factor (ARF) 1 from Golgi membranes. It also inhibits the membrane trafficking between the endoplasmic reticulum (ER) and the Golgi bodies.

EXO1 Preparation Products And Raw materials

Raw materials

Preparation Products

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EXO1 Suppliers

China 34 India 1 Russia 1 Switzerland 1 United Kingdom 1 United States 11 Global 49

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75541-83-2, EXO1Related Search:

4-FLUORO-BZ-2-ABZ-OME

2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER

2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE

2-(4-Fluoro-benzoylami

2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate

EOX 1

EXOCYTIC INHIBITOR 1

EXO1

Exo1, Exocytic Inhibitor 1, 2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester

EXOCYTIC INHIBITOR 1;NSC 214045;EXO 1;EXO-1

NSC 214045

Exo1 - CAS 75541-83-2 - Calbiochem

Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester

Exo 1 >=98% (HPLC), solid

Exo1,inhibit,Exo-1,Exo 1,Inhibitor

Methyl 2-(4-fluorobenzamido)benzoate

75541-83-2

C15H12NFO3